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polr2f polr2f LOC107088364 LOC107088364 tial1 tial1 LOC107095138 LOC107095138 KRAS KRAS fgfbp3 fgfbp3 polr2l polr2l LOC107102581 LOC107102581 polr2b polr2b hras hras LOC107089939 LOC107089939 Fgfbp2 Fgfbp2 plcg1 plcg1 ENSCVAP00000008530 ENSCVAP00000008530 FGF6 FGF6 mknk2 mknk2 SRC SRC grb2 grb2 pik3ca pik3ca polr2h polr2h LOC107091875 LOC107091875 ncbp2 ncbp2 LOC107089165 LOC107089165 LOC107093786 LOC107093786 LOC107085894 LOC107085894 polr2j polr2j polr2i polr2i FGF6-2 FGF6-2 LOC107101186 LOC107101186 LOC107098202 LOC107098202 LOC107083529 LOC107083529 ENSCVAP00000014703 ENSCVAP00000014703 LOC107088613 LOC107088613 LOC107084657 LOC107084657 POLR2C POLR2C mapk1 mapk1 LOC107101656 LOC107101656 LOC107082377 LOC107082377 fgf16 fgf16 fndc3b fndc3b LOC107102211 LOC107102211 POLR2E POLR2E fgf10 fgf10 LOC107100983 LOC107100983 polr2g polr2g fgf5 fgf5 ENSCVAP00000018298 ENSCVAP00000018298 ENSCVAP00000018644 ENSCVAP00000018644 ptbp3 ptbp3 fgf2 fgf2 shc1 shc1 fgf3 fgf3 mknk1 mknk1 esrp2 esrp2 ENSCVAP00000022018 ENSCVAP00000022018 LOC107089396 LOC107089396 fgf22 fgf22 cbl cbl NCBP1 NCBP1 PIK3CA PIK3CA esrp1 esrp1 fgf7 fgf7 uba52 uba52 LOC107088237 LOC107088237 frs2 frs2 ENSCVAP00000027360 ENSCVAP00000027360 gtf2f1 gtf2f1 ptbp1 ptbp1 LOC107089793 LOC107089793 LOC107090307 LOC107090307 gtf2f2 gtf2f2 fgf23 fgf23 LOC107083535 LOC107083535 LOC107098777 LOC107098777 fgfr2 fgfr2 ppp2r1b ppp2r1b fndc3a fndc3a fgf20 fgf20 LOC107096942 LOC107096942 LOC107087836 LOC107087836 ppp2ca ppp2ca polr2d polr2d CSDE1 CSDE1 ENSCVAP00000000999 ENSCVAP00000000999 Fgf4 Fgf4 LOC107099697 LOC107099697 rps27a rps27a polr2a polr2a
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
LOC107088364Polymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
tial1TIA1 cytotoxic granule-associated RNA binding protein-like 1. (370 aa)
LOC107095138Zgc:55558. (187 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
fgfbp3Fibroblast growth factor binding protein 3. (241 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
LOC107102581Fibroblast growth factor receptor substrate 3. (607 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC107089939Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (172 aa)
Fgfbp2Fibroblast growth factor binding protein 2b. (221 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1310 aa)
ENSCVAP00000008530Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (183 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
SRCTyrosine-protein kinase. (551 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1004 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
LOC107091875Heterogeneous nuclear ribonucleoprotein A1a. (338 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
LOC107089165Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC107093786Cytotoxic granule-associated RNA binding protein 1, like. (364 aa)
LOC107085894Serine/threonine-protein phosphatase. (309 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC107101186Mitogen-activated protein kinase. (379 aa)
LOC107098202Uncharacterized protein. (860 aa)
LOC107083529General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (253 aa)
ENSCVAP00000014703Fibroblast growth factor receptor 2. (372 aa)
LOC107088613Polypyrimidine tract binding protein 2b. (523 aa)
LOC107084657Serine/threonine-protein phosphatase. (309 aa)
POLR2CPolymerase (RNA) II (DNA directed) polypeptide C. (248 aa)
mapk1Mitogen-activated protein kinase. (351 aa)
LOC107101656Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (160 aa)
LOC107082377Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
fndc3bFibronectin type III domain containing 3Ba. (1207 aa)
LOC107102211Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
LOC107100983Heterogeneous nuclear ribonucleoprotein M. (689 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
ENSCVAP00000018298Uncharacterized protein. (438 aa)
ENSCVAP00000018644Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
ptbp3Uncharacterized protein. (554 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (443 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
mknk1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (461 aa)
esrp2Epithelial splicing regulatory protein 2. (742 aa)
ENSCVAP00000022018Uncharacterized protein. (54 aa)
LOC107089396PH domain-containing protein. (761 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (952 aa)
NCBP1Nuclear cap binding protein subunit 1. (813 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1038 aa)
esrp1Epithelial splicing regulatory protein 1. (753 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC107088237Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
frs2Fibroblast growth factor receptor substrate 2b. (531 aa)
ENSCVAP00000027360Fibroblast growth factor binding protein 1b. (246 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (504 aa)
ptbp1Polypyrimidine tract binding protein 1a. (577 aa)
LOC107089793Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa)
LOC107090307Sprouty RTK signaling antagonist 2. (351 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (268 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (276 aa)
LOC107083535Cbl proto-oncogene C, E3 ubiquitin protein ligase. (566 aa)
LOC107098777TIA1 cytotoxic granule-associated RNA binding protein. (387 aa)
fgfr2Fibroblast growth factor receptor 2. (655 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (589 aa)
fndc3aFibronectin type III domain containing 3A. (1234 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (227 aa)
LOC107096942Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC107087836DNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
ppp2caSerine/threonine-protein phosphatase. (314 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (907 aa)
ENSCVAP00000000999Uncharacterized protein; Belongs to the heparin-binding growth factors family. (167 aa)
Fgf4Fibroblast growth factor 4. (144 aa)
LOC107099697RPOLD domain-containing protein. (275 aa)
rps27aRibosomal protein S27a. (181 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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