43 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mus81	MUS81 structure-specific endonuclease subunit. (608 aa)
	fancd2	FA complementation group D2. (1437 aa)
	rpa3	Replication protein A3. (122 aa)
	EME2	ERCC4 domain-containing protein. (448 aa)
	atrip	Uncharacterized protein. (773 aa)
	rps27a	Ribosomal protein S27a. (181 aa)
	fancf	FA complementation group F. (341 aa)
	fanci	FA complementation group I. (1308 aa)
	usp1	Ubiquitin carboxyl-terminal hydrolase. (808 aa)
	nutf2	Nuclear transport factor 2. (127 aa)
	CENPS	Centromere protein S. (142 aa)
	LOC107103120	SLX1 homolog B, structure-specific endonuclease subunit. (218 aa)
	cenpx	Centromere protein X. (114 aa)
	LOC107087496	DNA cross-link repair 1B. (543 aa)
	LOC107088102	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (670 aa)
	eme1	Essential meiotic structure-specific endonuclease 1. (522 aa)
	LOC107101209	Ubiquitin-conjugating enzyme E2T (putative). (194 aa)
	wdr48	WD repeat domain 48b. (698 aa)
	fancm	Uncharacterized protein. (1764 aa)
	fancb	FA complementation group B. (726 aa)
	fancl	FA complementation group L. (371 aa)
	rpa2	Replication protein A2. (278 aa)
	dclre1a	DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (891 aa)
	proser1	Proline and serine rich 1. (782 aa)
	atr	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2502 aa)
	faap100	Uncharacterized protein. (791 aa)
	LOC107087406	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (911 aa)
	fancg	FA complementation group G. (522 aa)
	ENSCVAP00000026260	FA complementation group C. (427 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	ercc4	Excision repair cross-complementation group 4. (885 aa)
	ENSCVAP00000021667	Ubiquitin-like domain-containing protein. (83 aa)
	LOC107087852	NTF2 domain-containing protein. (128 aa)
	ENSCVAP00000019159	Methionine sulfoxide reductase B1b. (252 aa)
	ENSCVAP00000019055	Uncharacterized protein. (256 aa)
	Slx4	BTB domain-containing protein. (1002 aa)
	faap24	FA core complex associated protein 24. (218 aa)
	ENSCVAP00000017542	Fanconi_A_N domain-containing protein. (242 aa)
	ercc1	Excision repair cross-complementation group 1. (351 aa)
	ENSCVAP00000016466	Uncharacterized protein. (164 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
	DCLRE1B	DNA cross-link repair 1B. (460 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CENPS	ENSCVAP00000016466	ENSCVAP00000004826	ENSCVAP00000016466	Centromere protein S.	Uncharacterized protein.	0.523
CENPS	ENSCVAP00000017542	ENSCVAP00000004826	ENSCVAP00000017542	Centromere protein S.	Fanconi_A_N domain-containing protein.	0.862
CENPS	ENSCVAP00000019055	ENSCVAP00000004826	ENSCVAP00000019055	Centromere protein S.	Uncharacterized protein.	0.444
CENPS	ENSCVAP00000019159	ENSCVAP00000004826	ENSCVAP00000019159	Centromere protein S.	Methionine sulfoxide reductase B1b.	0.444
CENPS	ENSCVAP00000026260	ENSCVAP00000004826	ENSCVAP00000026260	Centromere protein S.	FA complementation group C.	0.797
CENPS	LOC107087406	ENSCVAP00000004826	ENSCVAP00000028572	Centromere protein S.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.446
CENPS	LOC107087852	ENSCVAP00000004826	ENSCVAP00000019728	Centromere protein S.	NTF2 domain-containing protein.	0.712
CENPS	LOC107088102	ENSCVAP00000004826	ENSCVAP00000011210	Centromere protein S.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.706
CENPS	LOC107101209	ENSCVAP00000004826	ENSCVAP00000012705	Centromere protein S.	Ubiquitin-conjugating enzyme E2T (putative).	0.546
CENPS	Slx4	ENSCVAP00000004826	ENSCVAP00000018954	Centromere protein S.	BTB domain-containing protein.	0.406
CENPS	atr	ENSCVAP00000004826	ENSCVAP00000030889	Centromere protein S.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.557
CENPS	cenpx	ENSCVAP00000004826	ENSCVAP00000009453	Centromere protein S.	Centromere protein X.	0.539
CENPS	dclre1a	ENSCVAP00000004826	ENSCVAP00000031656	Centromere protein S.	DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae).	0.492
CENPS	eme1	ENSCVAP00000004826	ENSCVAP00000012079	Centromere protein S.	Essential meiotic structure-specific endonuclease 1.	0.422
CENPS	ercc1	ENSCVAP00000004826	ENSCVAP00000016561	Centromere protein S.	Excision repair cross-complementation group 1.	0.621
CENPS	ercc4	ENSCVAP00000004826	ENSCVAP00000023074	Centromere protein S.	Excision repair cross-complementation group 4.	0.734
CENPS	faap100	ENSCVAP00000004826	ENSCVAP00000030317	Centromere protein S.	Uncharacterized protein.	0.723
CENPS	faap24	ENSCVAP00000004826	ENSCVAP00000018633	Centromere protein S.	FA core complex associated protein 24.	0.874
CENPS	fancb	ENSCVAP00000004826	ENSCVAP00000013651	Centromere protein S.	FA complementation group B.	0.815
CENPS	fancd2	ENSCVAP00000004826	ENSCVAP00000000141	Centromere protein S.	FA complementation group D2.	0.616