STRINGSTRING
psma2 psma2 psmd13 psmd13 psmf1 psmf1 gmnn gmnn LOC107103890 LOC107103890 gins4 gins4 psmc5 psmc5 pold4 pold4 psmb7 psmb7 cdc16 cdc16 cdc26 cdc26 ENSCVAP00000019055 ENSCVAP00000019055 rfc2 rfc2 ENSCVAP00000019159 ENSCVAP00000019159 LOC107100955 LOC107100955 psma8 psma8 ENSCVAP00000014272 ENSCVAP00000014272 orc4 orc4 pole3 pole3 psmc2 psmc2 fen1 fen1 ENSCVAP00000021171 ENSCVAP00000021171 anapc2 anapc2 ENSCVAP00000021667 ENSCVAP00000021667 pold2 pold2 psma4 psma4 psmb8 psmb8 LOC107104822 LOC107104822 LOC107104821 LOC107104821 RCBTB1 RCBTB1 cdt1 cdt1 LOC107093226 LOC107093226 psma5 psma5 pold1 pold1 ENSCVAP00000023062 ENSCVAP00000023062 ENSCVAP00000023072 ENSCVAP00000023072 psmb5 psmb5 psme3 psme3 kxd1 kxd1 cdc27 cdc27 rfc1 rfc1 cul1 cul1 ube2s ube2s LOC107100940 LOC107100940 LOC107100937 LOC107100937 fam89a fam89a ENSCVAP00000032196 ENSCVAP00000032196 FZR1 FZR1 ENSCVAP00000031743 ENSCVAP00000031743 psmd10 psmd10 orc3 orc3 mcm6 mcm6 orc5 orc5 mcm2 mcm2 rfc5 rfc5 psmc6 psmc6 anapc15 anapc15 mcm4 mcm4 anapc5 anapc5 psma1 psma1 anapc4 anapc4 LOC107084189 LOC107084189 ccna1 ccna1 rfc3 rfc3 ube2c ube2c cdc6 cdc6 bicral bicral ccna2 ccna2 pola2 pola2 psmd1 psmd1 psmc3 psmc3 uba52 uba52 rbx1 rbx1 dna2 dna2 skp2 skp2 LOC107082631 LOC107082631 psmb3 psmb3 psmd12 psmd12 LOC107089962 LOC107089962 anapc7 anapc7 cdc23 cdc23 LOC107103719 LOC107103719 anapc10 anapc10 prim1 prim1 orc2 orc2 psmd5 psmd5 bicra bicra ENSCVAP00000001347 ENSCVAP00000001347 psmb4 psmb4 mcm5 mcm5 LOC107096288 LOC107096288 LOC107102346 LOC107102346 psmd14 psmd14 pola1 pola1 LOC107094889 LOC107094889 skp1 skp1 LOC107088102 LOC107088102 orc1 orc1 LOC107080947 LOC107080947 ENSCVAP00000009946 ENSCVAP00000009946 psmc1 psmc1 pole pole LOC107095481 LOC107095481 anapc1 anapc1 lig1 lig1 psmb1 psmb1 LOC107092444 LOC107092444 LOC107098698 LOC107098698 LOC107103717 LOC107103717 psmc4 psmc4 prim2 prim2 ENSCVAP00000007460 ENSCVAP00000007460 psmd7 psmd7 tm7sf3 tm7sf3 psme4 psme4 psmd6 psmd6 psma3 psma3 cdk2 cdk2 mcm7 mcm7 psma6 psma6 LOC107091169 LOC107091169 psmd8 psmd8 rpa3 rpa3 gins2 gins2 rfc4 rfc4 ccne2 ccne2 gins3 gins3 ENSCVAP00000016466 ENSCVAP00000016466 rpa1 rpa1 pole4 pole4 LOC107101111 LOC107101111 LOC107095354 LOC107095354 psmd3 psmd3 Mcm9 Mcm9 ENSCVAP00000014940 ENSCVAP00000014940 PSMD6 PSMD6 psmb2 psmb2 rpa2 rpa2 LOC107104657 LOC107104657 anapc11 anapc11 LOC107094495 LOC107094495 ENSCVAP00000003828 ENSCVAP00000003828 anapc16 anapc16 rps27a rps27a psme2 psme2 gins1 gins1 pcna pcna mcm3 mcm3 pole2 pole2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
psma2Proteasome subunit alpha type. (234 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
psmf1Uncharacterized protein. (208 aa)
gmnnGeminin DNA replication inhibitor. (216 aa)
LOC107103890Proteasome activator subunit 1. (252 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (224 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
pold4Si:dkey-28b4.7. (107 aa)
psmb7Proteasome subunit beta. (286 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
cdc26Cell division cycle 26 homolog. (91 aa)
ENSCVAP00000019055Uncharacterized protein. (256 aa)
rfc2Replication factor C (activator 1) 2. (373 aa)
ENSCVAP00000019159Methionine sulfoxide reductase B1b. (252 aa)
LOC107100955Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
psma8Proteasome subunit alpha type. (251 aa)
ENSCVAP00000014272Uncharacterized protein. (184 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (447 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (146 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
ENSCVAP00000021171Proteasome activator subunit 1. (90 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (756 aa)
ENSCVAP00000021667Ubiquitin-like domain-containing protein. (83 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (487 aa)
psma4Proteasome subunit alpha type. (261 aa)
psmb8Proteasome subunit beta. (275 aa)
LOC107104822Proteasome subunit beta. (216 aa)
LOC107104821Proteasome subunit beta 12. (217 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (555 aa)
cdt1Chromatin licensing and DNA replication factor 1. (459 aa)
LOC107093226Proteasome 26S subunit, non-ATPase 11b. (422 aa)
psma5Proteasome subunit alpha type. (241 aa)
pold1DNA polymerase. (1105 aa)
ENSCVAP00000023062DUF3437 domain-containing protein. (322 aa)
ENSCVAP00000023072BLM10_mid domain-containing protein. (564 aa)
psmb5Proteasome subunit beta 5. (219 aa)
psme3Proteasome activator subunit 3. (256 aa)
kxd1KxDL motif containing 1. (184 aa)
cdc27Cell division cycle 27. (808 aa)
rfc1Replication factor C subunit 1. (1159 aa)
cul1Cullin 1b; Belongs to the cullin family. (776 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (234 aa)
LOC107100940UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
LOC107100937Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
fam89aFamily with sequence similarity 89 member A. (181 aa)
ENSCVAP00000032196Proteasome subunit beta. (274 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (497 aa)
ENSCVAP00000031743Cyclin E1; Belongs to the cyclin family. (259 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
orc3Origin recognition complex, subunit 3. (679 aa)
mcm6DNA helicase; Belongs to the MCM family. (824 aa)
orc5Origin recognition complex, subunit 5. (442 aa)
mcm2DNA helicase; Belongs to the MCM family. (878 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
anapc15Anaphase promoting complex subunit 15. (154 aa)
mcm4DNA helicase; Belongs to the MCM family. (853 aa)
anapc5Anaphase promoting complex subunit 5. (763 aa)
psma1Proteasome endopeptidase complex. (238 aa)
anapc4Anaphase promoting complex subunit 4. (741 aa)
LOC107084189Family with sequence similarity 89 member B. (153 aa)
ccna1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (389 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (569 aa)
bicralBRD4 interacting chromatin remodeling complex associated protein like. (746 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (432 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (604 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (969 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
dna2DNA replication helicase/nuclease 2. (1358 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (409 aa)
LOC107082631Fizzy/cell division cycle 20 related 1b. (503 aa)
psmb3Proteasome subunit beta. (205 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
LOC107089962Zgc:110269. (342 aa)
anapc7Anaphase promoting complex subunit 7. (591 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (574 aa)
LOC107103719Proteasome subunit beta 12. (217 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (425 aa)
orc2Origin recognition complex, subunit 2. (536 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
bicraBRD4 interacting chromatin remodeling complex associated protein. (1764 aa)
ENSCVAP00000001347SCY domain-containing protein. (126 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
mcm5DNA helicase; Belongs to the MCM family. (738 aa)
LOC107096288Proteasome 26S subunit, non-ATPase 4b. (375 aa)
LOC107102346PCI domain-containing protein. (410 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
pola1DNA polymerase. (1420 aa)
LOC107094889Proteasome subunit beta11b. (386 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (156 aa)
LOC107088102Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (670 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (854 aa)
LOC107080947Uncharacterized protein. (133 aa)
ENSCVAP00000009946MCM_OB domain-containing protein. (197 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (352 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2017 aa)
LOC107095481Proteasome subunit alpha type. (246 aa)
anapc1Anaphase promoting complex subunit 1. (1796 aa)
lig1DNA ligase. (1004 aa)
psmb1Proteasome subunit beta. (237 aa)
LOC107092444Polymerase (DNA-directed), delta 3, accessory subunit. (439 aa)
LOC107098698Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (428 aa)
LOC107103717Proteasome subunit beta. (224 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (349 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (505 aa)
ENSCVAP00000007460Proteasome subunit beta. (217 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (361 aa)
tm7sf3Transmembrane 7 superfamily member 3. (570 aa)
psme4Proteasome activator subunit 4a. (1829 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (313 aa)
psma3Proteasome subunit alpha type. (255 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa)
psma6Proteasome subunit alpha type. (246 aa)
LOC107091169ATPase family AAA domain containing 5a. (1526 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (265 aa)
rpa3Replication protein A3. (122 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
ccne2Cyclin E2; Belongs to the cyclin family. (345 aa)
gins3GINS complex subunit 3. (211 aa)
ENSCVAP00000016466Uncharacterized protein. (164 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
LOC107101111Proteasome 26S subunit, non-ATPase 4a. (372 aa)
LOC107095354Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (524 aa)
Mcm9MCM domain-containing protein; Belongs to the MCM family. (263 aa)
ENSCVAP00000014940Uncharacterized protein. (119 aa)
PSMD6PCI domain-containing protein. (389 aa)
psmb2Proteasome subunit beta. (199 aa)
rpa2Replication protein A2. (278 aa)
LOC107104657Proteasome subunit beta. (233 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
LOC107094495Proteasome subunit alpha type. (246 aa)
ENSCVAP00000003828Proteasome subunit beta. (276 aa)
anapc16Anaphase promoting complex subunit 16. (108 aa)
rps27aRibosomal protein S27a. (181 aa)
psme2Proteasome activator subunit 2. (245 aa)
gins1GINS complex subunit 1 (Psf1 homolog). (189 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
mcm3DNA helicase; Belongs to the MCM family. (814 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (529 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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