57 items (Cyprinodon variegatus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	ddx42	DEAD (Asp-Glu-Ala-Asp) box helicase 42. (901 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
	SNRPD2	Small nuclear ribonucleoprotein Sm D2. (121 aa)
	polr2b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
	snrnp40	Small nuclear ribonucleoprotein 40 (U5). (347 aa)
	LOC107089377	Uncharacterized protein. (247 aa)
	LOC107088364	Polymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
	polr2a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
	LOC107099697	RPOLD domain-containing protein. (275 aa)
	Snrnp70	Small nuclear ribonucleoprotein 70 (U1). (160 aa)
	sf3b1	Splicing factor 3b, subunit 1. (1268 aa)
	rnpc3	RNA-binding region (RNP1, RRM) containing 3. (512 aa)
	txnl4a	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	polr2d	Polymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
	sf3b4	Splicing factor 3b, subunit 4. (389 aa)
	sf3b5	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	sf3b6	Splicing factor 3b, subunit 6. (125 aa)
	YBX2	Y-box binding protein 2. (331 aa)
	zcrb1	Zinc finger CCHC-type and RNA binding motif 1. (220 aa)
	snrpd3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	sf3b2	Splicing factor 3b, subunit 2. (848 aa)
	LOC107087836	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
	srsf2	Serine and arginine rich splicing factor 2a. (232 aa)
	snrpe	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	LOC107090357	Serine and arginine rich splicing factor 1a. (245 aa)
	ENSCVAP00000030039	Uncharacterized protein. (375 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (268 aa)
	LOC107081054	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	gtf2f1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (504 aa)
	prpf6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae). (969 aa)
	sf3b3	Splicing factor 3b, subunit 3. (1217 aa)
	Prpf8	MPN domain-containing protein. (322 aa)
	ENSCVAP00000025291	Uncharacterized protein. (465 aa)
	NCBP1	Nuclear cap binding protein subunit 1. (813 aa)
	ybx1	Y box binding protein 1. (299 aa)
	zmat5	Zinc finger, matrin-type 5. (175 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
	zrsr2	Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2. (559 aa)
	snrpd1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
	LOC107092507	Serine and arginine rich splicing factor 7a. (259 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	snrnp48	Small nuclear ribonucleoprotein 48 (U11/U12). (387 aa)
	POLR2C	Polymerase (RNA) II (DNA directed) polypeptide C. (248 aa)
	snrnp200	Small nuclear ribonucleoprotein 200 (U5). (2056 aa)
	LOC107083529	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (253 aa)
	snrnp25	Small nuclear ribonucleoprotein 25. (184 aa)
	srsf7	Serine and arginine rich splicing factor 7b. (264 aa)
	ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (802 aa)
	Snrpf	Small nuclear ribonucleoprotein polypeptide F. (126 aa)
	polr2i	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
	polr2j	Polymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
	SNRPN	Small nuclear ribonucleoprotein-associated protein. (241 aa)
	ncbp2	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
	snrpg	Small nuclear ribonucleoprotein G. (76 aa)
	eftud2	Elongation factor Tu GTP binding domain containing 2. (1003 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000025291	LOC107081054	ENSCVAP00000025291	ENSCVAP00000028040	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D2.	0.925
ENSCVAP00000025291	LOC107089377	ENSCVAP00000025291	ENSCVAP00000004170	Uncharacterized protein.	Uncharacterized protein.	0.632
ENSCVAP00000025291	LOC107090357	ENSCVAP00000025291	ENSCVAP00000030220	Uncharacterized protein.	Serine and arginine rich splicing factor 1a.	0.632
ENSCVAP00000025291	NCBP1	ENSCVAP00000025291	ENSCVAP00000024554	Uncharacterized protein.	Nuclear cap binding protein subunit 1.	0.837
ENSCVAP00000025291	Prpf8	ENSCVAP00000025291	ENSCVAP00000025302	Uncharacterized protein.	MPN domain-containing protein.	0.900
ENSCVAP00000025291	SNRPD2	ENSCVAP00000025291	ENSCVAP00000008404	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D2.	0.925
ENSCVAP00000025291	SNRPN	ENSCVAP00000025291	ENSCVAP00000011861	Uncharacterized protein.	Small nuclear ribonucleoprotein-associated protein.	0.944
ENSCVAP00000025291	Snrnp70	ENSCVAP00000025291	ENSCVAP00000002768	Uncharacterized protein.	Small nuclear ribonucleoprotein 70 (U1).	0.781
ENSCVAP00000025291	Snrpf	ENSCVAP00000025291	ENSCVAP00000013124	Uncharacterized protein.	Small nuclear ribonucleoprotein polypeptide F.	0.968
ENSCVAP00000025291	ddx23	ENSCVAP00000025291	ENSCVAP00000013230	Uncharacterized protein.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	0.980
ENSCVAP00000025291	ddx42	ENSCVAP00000025291	ENSCVAP00000009403	Uncharacterized protein.	DEAD (Asp-Glu-Ala-Asp) box helicase 42.	0.486
ENSCVAP00000025291	eftud2	ENSCVAP00000025291	ENSCVAP00000010358	Uncharacterized protein.	Elongation factor Tu GTP binding domain containing 2.	0.998
ENSCVAP00000025291	ncbp2	ENSCVAP00000025291	ENSCVAP00000010612	Uncharacterized protein.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.877
ENSCVAP00000025291	polr2a	ENSCVAP00000025291	ENSCVAP00000003901	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.417
ENSCVAP00000025291	polr2b	ENSCVAP00000025291	ENSCVAP00000006138	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.529
ENSCVAP00000025291	prpf6	ENSCVAP00000025291	ENSCVAP00000025594	Uncharacterized protein.	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).	0.998
ENSCVAP00000025291	rnpc3	ENSCVAP00000025291	ENSCVAP00000001637	Uncharacterized protein.	RNA-binding region (RNP1, RRM) containing 3.	0.645
ENSCVAP00000025291	sf3b1	ENSCVAP00000025291	ENSCVAP00000002547	Uncharacterized protein.	Splicing factor 3b, subunit 1.	0.960
ENSCVAP00000025291	sf3b2	ENSCVAP00000025291	ENSCVAP00000021363	Uncharacterized protein.	Splicing factor 3b, subunit 2.	0.977
ENSCVAP00000025291	sf3b3	ENSCVAP00000025291	ENSCVAP00000025538	Uncharacterized protein.	Splicing factor 3b, subunit 3.	0.961