137 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCVAP00000030324	B30.2/SPRY domain-containing protein. (292 aa)
	ufd1	Ubiquitin recognition factor in ER associated degradation 1. (311 aa)
	rfc5	Replication factor C (activator 1) 5. (335 aa)
	ENSCVAP00000029795	Uncharacterized protein. (369 aa)
	LOC107091974	Uncharacterized protein. (541 aa)
	ENSCVAP00000028625	Uncharacterized protein. (206 aa)
	rchy1	Ring finger and CHY zinc finger domain containing 1. (273 aa)
	LOC107092035	Uncharacterized protein. (552 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	LOC107089758	Uncharacterized protein. (510 aa)
	ENSCVAP00000027550	Uncharacterized protein. (556 aa)
	ENSCVAP00000026881	Uncharacterized protein. (520 aa)
	usp43	Ubiquitin specific peptidase 43b; Belongs to the peptidase C19 family. (1207 aa)
	LOC107095499	Uncharacterized protein. (610 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
	ENSCVAP00000025529	RING-type domain-containing protein. (103 aa)
	ENSCVAP00000025140	B30.2/SPRY domain-containing protein. (191 aa)
	ENSCVAP00000025138	B30.2/SPRY domain-containing protein. (278 aa)
	ENSCVAP00000025107	Uncharacterized protein. (308 aa)
	ENSCVAP00000025091	Uncharacterized protein. (268 aa)
	ENSCVAP00000024939	RING-type domain-containing protein. (186 aa)
	LOC107084392	Uncharacterized protein. (401 aa)
	rfc1	Replication factor C subunit 1. (1159 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	pold1	DNA polymerase. (1105 aa)
	ENSCVAP00000022676	B30.2/SPRY domain-containing protein. (371 aa)
	ENSCVAP00000022640	Ig-like domain-containing protein. (192 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (555 aa)
	ENSCVAP00000022361	B30.2/SPRY domain-containing protein. (245 aa)
	polk	Polymerase (DNA directed) kappa. (905 aa)
	ENSCVAP00000021911	Uncharacterized protein. (497 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (487 aa)
	ENSCVAP00000021667	Ubiquitin-like domain-containing protein. (83 aa)
	Dtl	WD_REPEATS_REGION domain-containing protein. (142 aa)
	LOC107103864	Uncharacterized protein. (584 aa)
	ENSCVAP00000021241	RING-type domain-containing protein. (152 aa)
	pole	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2017 aa)
	LOC107084252	Uncharacterized protein. (602 aa)
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	ENSCVAP00000010348	Uncharacterized protein. (551 aa)
	LOC107088102	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (670 aa)
	LOC107092059	Uncharacterized protein. (544 aa)
	ENSCVAP00000012263	Uncharacterized protein. (277 aa)
	ENSCVAP00000012626	RING-type domain-containing protein. (243 aa)
	poli	Polymerase (DNA directed) iota. (618 aa)
	wdr48	WD repeat domain 48b. (698 aa)
	ENSCVAP00000013395	RING-type domain-containing protein. (366 aa)
	LOC107087396	Uncharacterized protein. (555 aa)
	ENSCVAP00000020379	B30.2/SPRY domain-containing protein. (223 aa)
	ENSCVAP00000013425	Uncharacterized protein. (550 aa)
	ENSCVAP00000013477	Uncharacterized protein. (560 aa)
	ENSCVAP00000013485	B30.2/SPRY domain-containing protein. (220 aa)
	ENSCVAP00000013499	Uncharacterized protein. (267 aa)
	LOC107083097	Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1283 aa)
	Polh	Polymerase (DNA directed), eta. (298 aa)
	mad2l2	Mitotic arrest deficient 2 like 2. (210 aa)
	LOC107099906	Si:dkey-24l11.2. (658 aa)
	ENSCVAP00000014536	Uncharacterized protein. (242 aa)
	rpa2	Replication protein A2. (278 aa)
	ENSCVAP00000014696	Uncharacterized protein. (276 aa)
	ENSCVAP00000014920	Uncharacterized protein. (237 aa)
	LOC107095354	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
	rev1	REV1 DNA directed polymerase. (1355 aa)
	ENSCVAP00000015825	RING-type domain-containing protein. (186 aa)
	ENSCVAP00000015896	Uncharacterized protein. (247 aa)
	ENSCVAP00000015917	Uncharacterized protein. (269 aa)
	ENSCVAP00000015945	Uncharacterized protein. (262 aa)
	pole4	Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
	pclaf	PCNA clamp associated factor. (116 aa)
	ENSCVAP00000016466	Uncharacterized protein. (164 aa)
	ddb1	Damage-specific DNA binding protein 1. (1080 aa)
	ENSCVAP00000017046	Si:dkey-46i9.6. (362 aa)
	LOC107084015	Uncharacterized protein. (549 aa)
	rfc4	Replication factor C (activator 1) 4. (357 aa)
	LOC107081714	Uncharacterized protein. (568 aa)
	ENSCVAP00000020218	Uncharacterized protein. (535 aa)
	ENSCVAP00000020078	Uncharacterized protein. (215 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (877 aa)
	ENSCVAP00000019698	PRY domain-containing protein. (270 aa)
	rev3l	REV3 like, DNA directed polymerase zeta catalytic subunit. (2776 aa)
	LOC107103945	Uncharacterized protein. (558 aa)
	pole3	Polymerase (DNA directed), epsilon 3 (p17 subunit). (146 aa)
	LOC107100955	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
	ENSCVAP00000019159	Methionine sulfoxide reductase B1b. (252 aa)
	rfc2	Replication factor C (activator 1) 2. (373 aa)
	ENSCVAP00000019055	Uncharacterized protein. (256 aa)
	ENSCVAP00000018342	Uncharacterized protein. (405 aa)
	nploc4	NPL4 homolog, ubiquitin recognition factor. (628 aa)
	pold4	Si:dkey-28b4.7. (107 aa)
	rad18	RAD18 E3 ubiquitin protein ligase. (495 aa)
	rpa3	Replication protein A3. (122 aa)
	LOC107081712	FinTRIM family, member 67. (453 aa)
	ENSCVAP00000000775	Uncharacterized protein. (238 aa)
	ENSCVAP00000000787	Uncharacterized protein. (484 aa)
	ENSCVAP00000001347	SCY domain-containing protein. (126 aa)
	LOC107091169	ATPase family AAA domain containing 5a. (1526 aa)
	LOC107090603	Uncharacterized protein. (497 aa)
	LOC107090604	Uncharacterized protein. (508 aa)
	ENSCVAP00000001971	B30.2/SPRY domain-containing protein. (325 aa)
	ENSCVAP00000001973	B30.2/SPRY domain-containing protein. (217 aa)
	pole2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (529 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	ENSCVAP00000003062	Uncharacterized protein. (520 aa)
	ENSCVAP00000003106	Uncharacterized protein. (501 aa)
	ENSCVAP00000003378	Uncharacterized protein. (247 aa)
	rps27a	Ribosomal protein S27a. (181 aa)
	LOC107096133	Uncharacterized protein. (552 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (863 aa)
	LOC107096137	Ig-like domain-containing protein. (237 aa)
	ENSCVAP00000004476	Ig-like domain-containing protein. (362 aa)
	usp1	Ubiquitin carboxyl-terminal hydrolase. (808 aa)
	ENSCVAP00000004903	Pyrin domain-containing protein. (255 aa)
	LOC107086707	Tripartite motif containing 25, like. (787 aa)
	LOC107094432	Uncharacterized protein. (545 aa)
	LOC107100204	Uncharacterized protein. (544 aa)
	ENSCVAP00000006385	Uncharacterized protein. (306 aa)
	ENSCVAP00000007378	B30.2/SPRY domain-containing protein. (188 aa)
	cul4a	Cullin 4A; Belongs to the cullin family. (612 aa)
	LOC107094393	Zgc:136908; Belongs to the AAA ATPase family. (808 aa)
	ENSCVAP00000007415	RING-type domain-containing protein. (87 aa)
	ENSCVAP00000007420	RING-type domain-containing protein. (92 aa)
	ENSCVAP00000007674	Uncharacterized protein. (566 aa)
	ENSCVAP00000007679	RING-type domain-containing protein. (80 aa)
	LOC107101371	Uncharacterized protein. (559 aa)
	ENSCVAP00000007962	Uncharacterized protein. (558 aa)
	ENSCVAP00000007991	Uncharacterized protein. (555 aa)
	LOC107092444	Polymerase (DNA-directed), delta 3, accessory subunit. (439 aa)
	spata5l1	Spermatogenesis associated 5-like 1. (749 aa)
	ENSCVAP00000008533	RING-type domain-containing protein. (123 aa)
	LOC107087012	Uncharacterized protein. (550 aa)
	SPATA5	Spermatogenesis associated 5. (894 aa)
	Sprtn	SprT-like N-terminal domain. (242 aa)
	LOC107084004	Bloodthirsty-related gene family, member 12. (568 aa)
	ENSCVAP00000030621	B30.2/SPRY domain-containing protein. (284 aa)
	ENSCVAP00000030387	B30.2/SPRY domain-containing protein. (224 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dtl	ENSCVAP00000016466	ENSCVAP00000021603	ENSCVAP00000016466	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.563
Dtl	ENSCVAP00000019055	ENSCVAP00000021603	ENSCVAP00000019055	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.470
Dtl	ENSCVAP00000019159	ENSCVAP00000021603	ENSCVAP00000019159	WD_REPEATS_REGION domain-containing protein.	Methionine sulfoxide reductase B1b.	0.470
Dtl	ENSCVAP00000021667	ENSCVAP00000021603	ENSCVAP00000021667	WD_REPEATS_REGION domain-containing protein.	Ubiquitin-like domain-containing protein.	0.653
Dtl	LOC107088102	ENSCVAP00000021603	ENSCVAP00000011210	WD_REPEATS_REGION domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.530
Dtl	LOC107091169	ENSCVAP00000021603	ENSCVAP00000001775	WD_REPEATS_REGION domain-containing protein.	ATPase family AAA domain containing 5a.	0.847
Dtl	LOC107092444	ENSCVAP00000021603	ENSCVAP00000008412	WD_REPEATS_REGION domain-containing protein.	Polymerase (DNA-directed), delta 3, accessory subunit.	0.666
Dtl	cul4a	ENSCVAP00000021603	ENSCVAP00000007408	WD_REPEATS_REGION domain-containing protein.	Cullin 4A; Belongs to the cullin family.	0.942
Dtl	cul4b	ENSCVAP00000021603	ENSCVAP00000003895	WD_REPEATS_REGION domain-containing protein.	Cullin 4B; Belongs to the cullin family.	0.942
Dtl	ddb1	ENSCVAP00000021603	ENSCVAP00000016510	WD_REPEATS_REGION domain-containing protein.	Damage-specific DNA binding protein 1.	0.996
Dtl	pclaf	ENSCVAP00000021603	ENSCVAP00000017463	WD_REPEATS_REGION domain-containing protein.	PCNA clamp associated factor.	0.588
Dtl	pcna	ENSCVAP00000021603	ENSCVAP00000002844	WD_REPEATS_REGION domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.975
Dtl	pold1	ENSCVAP00000021603	ENSCVAP00000023009	WD_REPEATS_REGION domain-containing protein.	DNA polymerase.	0.744
Dtl	pold2	ENSCVAP00000021603	ENSCVAP00000021723	WD_REPEATS_REGION domain-containing protein.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.693
Dtl	pold4	ENSCVAP00000021603	ENSCVAP00000017933	WD_REPEATS_REGION domain-containing protein.	Si:dkey-28b4.7.	0.457
Dtl	pole	ENSCVAP00000021603	ENSCVAP00000009733	WD_REPEATS_REGION domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.847
Dtl	pole2	ENSCVAP00000021603	ENSCVAP00000002721	WD_REPEATS_REGION domain-containing protein.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.770
Dtl	pole3	ENSCVAP00000021603	ENSCVAP00000019519	WD_REPEATS_REGION domain-containing protein.	Polymerase (DNA directed), epsilon 3 (p17 subunit).	0.652
Dtl	rad18	ENSCVAP00000021603	ENSCVAP00000000155	WD_REPEATS_REGION domain-containing protein.	RAD18 E3 ubiquitin protein ligase.	0.740
Dtl	rbx1	ENSCVAP00000021603	ENSCVAP00000025530	WD_REPEATS_REGION domain-containing protein.	Ring-box 1, E3 ubiquitin protein ligase.	0.976