36 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCVAP00000019553	Vitellogenin domain-containing protein. (429 aa)
	soat1	O-acyltransferase. (570 aa)
	npc2	Niemann-Pick disease, type C2. (167 aa)
	npc1	Niemann-Pick disease, type C1. (1270 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	LOC107081658	Apolipoprotein Bb, tandem duplicate 2. (3721 aa)
	ENSCVAP00000001456	Vitellogenin domain-containing protein. (808 aa)
	LOC107103921	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (948 aa)
	ENSCVAP00000002020	Vitellogenin domain-containing protein. (110 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (669 aa)
	LOC107094513	Vitellogenin 3, phosvitinless. (1236 aa)
	LOC107103201	Uncharacterized protein. (406 aa)
	LOC107103788	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family. (1094 aa)
	ENSCVAP00000004613	COesterase domain-containing protein. (242 aa)
	ENSCVAP00000007995	Sterol O-acyltransferase 2; Belongs to the membrane-bound acyltransferase family. (331 aa)
	ENSCVAP00000012583	Uncharacterized protein. (58 aa)
	ildr2	Immunoglobulin-like domain containing receptor 2. (541 aa)
	LOC107083578	Lipolysis stimulated lipoprotein receptor. (614 aa)
	LOC107080755	Low density lipoprotein receptor a. (859 aa)
	LOC107082788	Low density lipoprotein receptor b. (857 aa)
	LOC107087223	Vitellogenin 5. (1625 aa)
	ENSCVAP00000021184	VWFD domain-containing protein. (129 aa)
	ENSCVAP00000021193	VWFD domain-containing protein. (133 aa)
	ENSCVAP00000021825	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (386 aa)
	ENSCVAP00000022923	COesterase domain-containing protein. (94 aa)
	LOC107101473	Alpha_adaptinC2 domain-containing protein. (841 aa)
	LOC107082548	Ig-like domain-containing protein. (674 aa)
	LOC107090935	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (596 aa)
	LOC107090293	AP complex subunit beta. (919 aa)
	ap2m1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
	LOC107093711	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (556 aa)
	LOC107098745	Apolipoprotein Ba. (4081 aa)
	LOC107093644	Low density lipoprotein receptor adaptor protein 1a. (307 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (323 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (232 aa)
	ENSCVAP00000020812	Uncharacterized protein. (420 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000001456	ENSCVAP00000020812	ENSCVAP00000001456	ENSCVAP00000020812	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.657
ENSCVAP00000001456	ENSCVAP00000021825	ENSCVAP00000001456	ENSCVAP00000021825	Vitellogenin domain-containing protein.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.593
ENSCVAP00000001456	LOC107080755	ENSCVAP00000001456	ENSCVAP00000012801	Vitellogenin domain-containing protein.	Low density lipoprotein receptor a.	0.471
ENSCVAP00000001456	LOC107082788	ENSCVAP00000001456	ENSCVAP00000021128	Vitellogenin domain-containing protein.	Low density lipoprotein receptor b.	0.471
ENSCVAP00000001456	LOC107093644	ENSCVAP00000001456	ENSCVAP00000015162	Vitellogenin domain-containing protein.	Low density lipoprotein receptor adaptor protein 1a.	0.556
ENSCVAP00000001456	LOC107103921	ENSCVAP00000001456	ENSCVAP00000021034	Vitellogenin domain-containing protein.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.442
ENSCVAP00000001456	ap2m1	ENSCVAP00000001456	ENSCVAP00000031359	Vitellogenin domain-containing protein.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.443
ENSCVAP00000001456	ldlrap1	ENSCVAP00000001456	ENSCVAP00000016700	Vitellogenin domain-containing protein.	Low density lipoprotein receptor adaptor protein 1b.	0.618
ENSCVAP00000001456	npc2	ENSCVAP00000001456	ENSCVAP00000019385	Vitellogenin domain-containing protein.	Niemann-Pick disease, type C2.	0.564
ENSCVAP00000001456	pcsk9	ENSCVAP00000001456	ENSCVAP00000002780	Vitellogenin domain-containing protein.	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	0.412
ENSCVAP00000002020	ENSCVAP00000021184	ENSCVAP00000002020	ENSCVAP00000021184	Vitellogenin domain-containing protein.	VWFD domain-containing protein.	0.518
ENSCVAP00000002020	ENSCVAP00000021193	ENSCVAP00000002020	ENSCVAP00000021193	Vitellogenin domain-containing protein.	VWFD domain-containing protein.	0.516
ENSCVAP00000002020	ENSCVAP00000021825	ENSCVAP00000002020	ENSCVAP00000021825	Vitellogenin domain-containing protein.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.495
ENSCVAP00000002020	npc2	ENSCVAP00000002020	ENSCVAP00000019385	Vitellogenin domain-containing protein.	Niemann-Pick disease, type C2.	0.509
ENSCVAP00000012583	LOC107093644	ENSCVAP00000012583	ENSCVAP00000015162	Uncharacterized protein.	Low density lipoprotein receptor adaptor protein 1a.	0.712
ENSCVAP00000012583	LOC107101473	ENSCVAP00000012583	ENSCVAP00000023523	Uncharacterized protein.	Alpha_adaptinC2 domain-containing protein.	0.887
ENSCVAP00000012583	LOC107103921	ENSCVAP00000012583	ENSCVAP00000021034	Uncharacterized protein.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.925
ENSCVAP00000012583	ap2m1	ENSCVAP00000012583	ENSCVAP00000031359	Uncharacterized protein.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.949
ENSCVAP00000012583	ap2s1	ENSCVAP00000012583	ENSCVAP00000017307	Uncharacterized protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.947
ENSCVAP00000012583	clta	ENSCVAP00000012583	ENSCVAP00000017055	Uncharacterized protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.855