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sesn1 sesn1 wdr24 wdr24 ENSCVAP00000001977 ENSCVAP00000001977 atp6v1c2 atp6v1c2 atp6v1d atp6v1d ATP6V0C ATP6V0C LOC107089445 LOC107089445 Depdc5 Depdc5 LOC107104603 LOC107104603 CRYBB3 CRYBB3 dmrt2 dmrt2 dmrt3 dmrt3 LOC107101194 LOC107101194 lamtor3 lamtor3 LOC107088230 LOC107088230 cnst cnst atp6v1h atp6v1h Seh1l Seh1l atp6v1f atp6v1f sec13 sec13 DMRTA1 DMRTA1 txndc11 txndc11 LOC107085735 LOC107085735 nprl3 nprl3 itfg2 itfg2 LOC107094261 LOC107094261 lamtor1 lamtor1 rragc rragc LOC107082975 LOC107082975 ENSCVAP00000015681 ENSCVAP00000015681 LOC107092565 LOC107092565 LOC107095317 LOC107095317 lamtor2 lamtor2 LOC107103355 LOC107103355 LOC107092448 LOC107092448 mlst8 mlst8 CASTOR1 CASTOR1 ENSCVAP00000019147 ENSCVAP00000019147 LOC107098042 LOC107098042 dmrta2 dmrta2 atp6v0b atp6v0b BMT2 BMT2 LOC107104094 LOC107104094 LOC107104022 LOC107104022 LOC107087875 LOC107087875 atp6v1c1 atp6v1c1 ENSCVAP00000032381 ENSCVAP00000032381 LOC107082805 LOC107082805 LOC107090505 LOC107090505 LOC107104795 LOC107104795 rheb rheb fnip1 fnip1 Szt2 Szt2 mios mios LOC107102946 LOC107102946 atp6v0e1 atp6v0e1 lamtor5 lamtor5 macc1 macc1 kptn kptn slc38a9 slc38a9 mettl25 mettl25 LOC107083256 LOC107083256 LOC107083386 LOC107083386 flcn flcn lamtor4 lamtor4 rptor rptor atp6v1b2 atp6v1b2 LOC107083298 LOC107083298 atp6v0d1 atp6v0d1 nprl2 nprl2 atp6v1a atp6v1a atp6v1e1 atp6v1e1 LOC107095671 LOC107095671 SZT2 SZT2 rhebl1 rhebl1 mtor mtor wdr59 wdr59
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sesn1Sestrin 1. (548 aa)
wdr24WD repeat domain 24. (787 aa)
ENSCVAP00000001977ATPase H+ transporting V0 subunit e2. (51 aa)
atp6v1c2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (368 aa)
atp6v1dATPase H+ transporting V1 subunit D. (248 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
LOC107089445Crystallin, gamma N1; Belongs to the beta/gamma-crystallin family. (183 aa)
Depdc5Uncharacterized protein. (276 aa)
LOC107104603Uncharacterized protein. (617 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (237 aa)
dmrt2Doublesex and mab-3 related transcription factor 2a. (521 aa)
dmrt3Doublesex and mab-3 related transcription factor 3a. (531 aa)
LOC107101194V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
lamtor3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
LOC107088230V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa)
cnstConsortin_C domain-containing protein. (789 aa)
atp6v1hV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (484 aa)
Seh1lSEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (188 aa)
atp6v1fV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
sec13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
DMRTA1DMRT like family A1. (423 aa)
txndc11Thioredoxin domain containing 11. (843 aa)
LOC107085735ATPase H+ transporting V1 subunit E1b. (226 aa)
nprl3NPR3-like, GATOR1 complex subunit. (612 aa)
itfg2Integrin alpha FG-GAP repeat containing 2. (433 aa)
LOC107094261Uncharacterized protein. (375 aa)
lamtor1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
rragcRas-related GTP binding Ca. (382 aa)
LOC107082975Uncharacterized protein. (174 aa)
ENSCVAP00000015681Uncharacterized protein. (124 aa)
LOC107092565Si:zfos-80g12.1. (444 aa)
LOC107095317CBM21 domain-containing protein. (1398 aa)
lamtor2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
LOC107103355Crystallin, gamma N2; Belongs to the beta/gamma-crystallin family. (183 aa)
LOC107092448V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (260 aa)
CASTOR1Cytosolic arginine sensor for mTORC1 subunit 1. (334 aa)
ENSCVAP00000019147WD_REPEATS_REGION domain-containing protein. (66 aa)
LOC107098042V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
dmrta2DMRT-like family A2. (447 aa)
atp6v0bATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (211 aa)
BMT2S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (324 aa)
LOC107104094CBM21 domain-containing protein. (1196 aa)
LOC107104022SH3-domain binding protein 4. (957 aa)
LOC107087875Ras-related GTP binding A. (315 aa)
atp6v1c1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (383 aa)
ENSCVAP00000032381WD_REPEATS_REGION domain-containing protein. (68 aa)
LOC107082805SH3-domain binding protein 4a. (955 aa)
LOC107090505Si:ch211-125a15.1. (423 aa)
LOC107104795DM domain-containing protein. (447 aa)
rhebUncharacterized protein. (183 aa)
fnip1Folliculin interacting protein 1. (1230 aa)
Szt2Uncharacterized protein. (211 aa)
miosMissing oocyte, meiosis regulator, homolog (Drosophila). (823 aa)
LOC107102946Crystallin, beta B3; Belongs to the beta/gamma-crystallin family. (221 aa)
atp6v0e1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
lamtor5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
macc1MET transcriptional regulator MACC1. (844 aa)
kptnKaptin (actin binding protein). (424 aa)
slc38a9Solute carrier family 38 member 9. (527 aa)
mettl25Methyltransferase like 25. (569 aa)
LOC107083256Lens intrinsic membrane protein 2.4. (191 aa)
LOC107083386Lens intrinsic membrane protein 2.3. (173 aa)
flcnFolliculin. (556 aa)
lamtor4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (100 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1373 aa)
atp6v1b2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (503 aa)
LOC107083298Sestrin 2. (553 aa)
atp6v0d1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
nprl2NPR2 like, GATOR1 complex subunit. (378 aa)
atp6v1aATPase H+ transporting V1 subunit A. (617 aa)
atp6v1e1ATPase H+ transporting V1 subunit E1a. (226 aa)
LOC107095671Consortin, connexin sorting protein b. (374 aa)
SZT2SZT2 subunit of KICSTOR complex. (1950 aa)
rhebl1Ras homolog, mTORC1 binding like 1. (184 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2406 aa)
wdr59WD repeat domain 59. (884 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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