STRINGSTRING
gna12 gna12 rgs14 rgs14 SRC SRC PRKCA PRKCA mapk1 mapk1 traf3ip2 traf3ip2 mtor mtor fzd10 fzd10 tp53 tp53 jag1 jag1 LOC107102542 LOC107102542 BAX BAX stat1 stat1 apln apln dvl1 dvl1 nfkbia nfkbia LOC107086288 LOC107086288 LOC107098934 LOC107098934 traf3 traf3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gna12G protein subunit alpha 12. (385 aa)
rgs14Regulator of G protein signaling 14a. (576 aa)
SRCTyrosine-protein kinase. (551 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
mapk1Mitogen-activated protein kinase. (351 aa)
traf3ip2SEFIR domain-containing protein. (290 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2406 aa)
fzd10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (598 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (351 aa)
jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1250 aa)
LOC107102542Zgc:86598; Belongs to the protein kinase superfamily. (412 aa)
BAXBCL2 associated X, apoptosis regulator. (191 aa)
stat1Signal transducer and activator of transcription. (787 aa)
aplnUncharacterized protein. (74 aa)
dvl1Dishevelled segment polarity protein 1a. (720 aa)
nfkbiaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (319 aa)
LOC107086288Oxytocin; Belongs to the vasopressin/oxytocin family. (155 aa)
LOC107098934Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (885 aa)
traf3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (590 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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