node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC107096469 | bdh2 | ENSCVAP00000029559 | ENSCVAP00000010966 | 3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 3-hydroxybutyrate dehydrogenase, type 2. | 0.937 |
LOC107096469 | hmgcl | ENSCVAP00000029559 | ENSCVAP00000007087 | 3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.938 |
LOC107096469 | oxct1 | ENSCVAP00000029559 | ENSCVAP00000009276 | 3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.960 |
LOC107102750 | acat1 | ENSCVAP00000031732 | ENSCVAP00000015963 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.994 |
LOC107102750 | acat2 | ENSCVAP00000031732 | ENSCVAP00000020413 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.996 |
LOC107102750 | hmgcl | ENSCVAP00000031732 | ENSCVAP00000007087 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.993 |
LOC107102750 | oxct1 | ENSCVAP00000031732 | ENSCVAP00000009276 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.962 |
acat1 | LOC107102750 | ENSCVAP00000015963 | ENSCVAP00000031732 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.994 |
acat1 | acat2 | ENSCVAP00000015963 | ENSCVAP00000020413 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.907 |
acat1 | hmgcl | ENSCVAP00000015963 | ENSCVAP00000007087 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.941 |
acat1 | oxct1 | ENSCVAP00000015963 | ENSCVAP00000009276 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.970 |
acat2 | LOC107102750 | ENSCVAP00000020413 | ENSCVAP00000031732 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.996 |
acat2 | acat1 | ENSCVAP00000020413 | ENSCVAP00000015963 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.907 |
acat2 | hmgcl | ENSCVAP00000020413 | ENSCVAP00000007087 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.941 |
acat2 | oxct1 | ENSCVAP00000020413 | ENSCVAP00000009276 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.970 |
bdh2 | LOC107096469 | ENSCVAP00000010966 | ENSCVAP00000029559 | 3-hydroxybutyrate dehydrogenase, type 2. | 3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.937 |
bdh2 | hmgcl | ENSCVAP00000010966 | ENSCVAP00000007087 | 3-hydroxybutyrate dehydrogenase, type 2. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.932 |
bdh2 | oxct1 | ENSCVAP00000010966 | ENSCVAP00000009276 | 3-hydroxybutyrate dehydrogenase, type 2. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.937 |
hmgcl | LOC107096469 | ENSCVAP00000007087 | ENSCVAP00000029559 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.938 |
hmgcl | LOC107102750 | ENSCVAP00000007087 | ENSCVAP00000031732 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.993 |