STRINGSTRING
pgls pgls LOC107093359 LOC107093359 me1 me1 LOC107093320 LOC107093320 LOC107093319 LOC107093319 adpgk adpgk suclg2 suclg2 TKT TKT got2 got2 SHMT2 SHMT2 idh3a idh3a LOC107095812 LOC107095812 idh1 idh1 LOC107081991 LOC107081991 Prps2 Prps2 LOC107089440 LOC107089440 echs1 echs1 glud1 glud1 agxt agxt ehhadh ehhadh pgk1 pgk1 aldoc aldoc pfkm pfkm LOC107091043 LOC107091043 glyctk glyctk eno1 eno1 acss2 acss2 ppp1r16a ppp1r16a psph psph LOC107096720 LOC107096720 OGDH OGDH acads acads esd esd LOC107087052 LOC107087052 hao2 hao2 LOC107092161 LOC107092161 LOC107100101 LOC107100101 ACO2 ACO2 LOC107092158 LOC107092158 amt amt LOC107095500 LOC107095500 psat1 psat1 LOC107090948 LOC107090948 mmut mmut suclg1 suclg1 dlat dlat LOC107100573 LOC107100573 LOC107100590 LOC107100590 LOC107102308 LOC107102308 LOC107090866 LOC107090866 mcee mcee gldc gldc pc pc LOC107088625 LOC107088625 LOC107096511 LOC107096511 LOC107096505 LOC107096505 LOC107104203 LOC107104203 LOC107094836 LOC107094836 LOC107104201 LOC107104201 pgd pgd LOC107082437 LOC107082437 LOC107085779 LOC107085779 SDS SDS LOC107087967 LOC107087967 LOC107094766 LOC107094766 LOC107090040 LOC107090040 pkm pkm acat1 acat1 pccb pccb taldo1 taldo1 LOC107099816 LOC107099816 rgn rgn aco1 aco1 Mdh2 Mdh2 pgp pgp LOC107098687 LOC107098687 LOC107083965 LOC107083965 LOC107092408 LOC107092408 pdhb pdhb acss1 acss1 SDHB SDHB sucla2 sucla2 sdsl sdsl tpi1 tpi1 eno2 eno2 gapdh gapdh ENSCVAP00000020168 ENSCVAP00000020168 mthfr mthfr acat2 acat2 LOC107092894 LOC107092894 LOC107094661 LOC107094661 LOC107095807 LOC107095807 Fh Fh rpia rpia LOC107086110 LOC107086110 sdha sdha sdhd sdhd LOC107090538 LOC107090538 LOC107094037 LOC107094037 LOC107101528 LOC107101528 LOC107086089 LOC107086089 LOC107086115 LOC107086115 LOC107097190 LOC107097190 h6pd h6pd LOC107088352 LOC107088352 idh3b idh3b shmt2 shmt2 cs cs pcca pcca dld dld me2 me2 acox3 acox3 LOC107081772 LOC107081772 cps1 cps1 LOC107104202 LOC107104202 LOC107085778 LOC107085778 LOC107085782 LOC107085782 LOC107082426 LOC107082426 LOC107104610 LOC107104610 LOC107091900 LOC107091900 cat cat gck gck gpi gpi LOC107089056 LOC107089056 LOC107081709 LOC107081709 phgdh phgdh LOC107081479 LOC107081479 hadha hadha hibch hibch aldh6a1 aldh6a1 LOC107086791 LOC107086791
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
pgls6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (253 aa)
LOC107093359Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (360 aa)
me1Malic enzyme. (588 aa)
LOC107093320Aminotran_1_2 domain-containing protein. (435 aa)
LOC107093319Aminotran_1_2 domain-containing protein. (445 aa)
adpgkADP-dependent glucokinase. (494 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
TKTTransketolase. (628 aa)
got2Aspartate aminotransferase. (428 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (531 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
LOC107095812Zgc:77938. (388 aa)
idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
LOC107081991Aspartate aminotransferase. (410 aa)
Prps2Pribosyltran_N domain-containing protein. (169 aa)
LOC107089440Acetyl-coenzyme A synthetase. (673 aa)
echs1Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
glud1Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (545 aa)
agxtSerine--pyruvate aminotransferase. (429 aa)
ehhadhEnoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (733 aa)
pgk1Phosphoglycerate kinase. (417 aa)
aldocFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
pfkmATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (779 aa)
LOC107091043Aconitase 2, mitochondrial. (744 aa)
glyctkGlycerate kinase. (524 aa)
eno1Enolase 1a, (alpha). (432 aa)
acss2Acyl-CoA synthetase short chain family member 2. (698 aa)
ppp1r16aSi:ch211-217a12.1. (997 aa)
psphPhosphoserine phosphatase. (244 aa)
LOC107096720Pyruvate kinase; Belongs to the pyruvate kinase family. (535 aa)
OGDHOxoglutarate dehydrogenase. (1041 aa)
acadsAcyl-CoA dehydrogenase short chain. (411 aa)
esdS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (334 aa)
LOC107087052Transketolase b. (626 aa)
hao2Hydroxyacid oxidase 2 (long chain). (370 aa)
LOC107092161Hexokinase 1. (918 aa)
LOC107100101Enolase 1b, (alpha). (434 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
LOC107092158ADP-dependent glucokinase 2. (493 aa)
amtAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (412 aa)
LOC107095500Triokinase/FMN cyclase. (489 aa)
psat1Phosphoserine aminotransferase. (373 aa)
LOC107090948Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (255 aa)
mmutMethylmalonyl CoA mutase. (754 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (324 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (633 aa)
LOC107100573Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
LOC107100590Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
LOC107102308Enolase 3, (beta, muscle). (534 aa)
LOC107090866Aldedh domain-containing protein. (481 aa)
mceeMethylmalonyl CoA epimerase. (173 aa)
gldcGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1067 aa)
pcPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1180 aa)
LOC107088625Malate dehydrogenase. (350 aa)
LOC107096511Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family. (337 aa)
LOC107096505Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family. (338 aa)
LOC107104203Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (464 aa)
LOC107094836Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (513 aa)
LOC107104201Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (500 aa)
pgd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
LOC107082437Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
LOC107085779PKS_ER domain-containing protein. (378 aa)
SDSSerine dehydratase. (223 aa)
LOC107087967Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (453 aa)
LOC107094766Transketolase a. (628 aa)
LOC107090040Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
pkmPyruvate kinase; Belongs to the pyruvate kinase family. (629 aa)
acat1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
pccbPropionyl-CoA carboxylase subunit beta. (560 aa)
taldo1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (375 aa)
LOC107099816Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
rgnRegucalcin. (300 aa)
aco1Aconitase 1, soluble. (857 aa)
Mdh2Ldh_1_N domain-containing protein. (163 aa)
pgpPhosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (306 aa)
LOC107098687Uncharacterized protein. (923 aa)
LOC107083965ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (788 aa)
LOC107092408Dihydrolipoamide S-succinyltransferase. (461 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
acss1Acetyl-coenzyme A synthetase. (680 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (283 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (466 aa)
sdslSerine dehydratase-like. (322 aa)
tpi1Triosephosphate isomerase. (247 aa)
eno2Uncharacterized protein. (434 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
ENSCVAP00000020168PFK domain-containing protein. (221 aa)
mthfrMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (661 aa)
acat2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (438 aa)
LOC107092894Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (279 aa)
LOC107094661Hexokinase 2. (912 aa)
LOC107095807S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (376 aa)
FhLyase_1 domain-containing protein. (137 aa)
rpiaRibose 5-phosphate isomerase A (ribose 5-phosphate epimerase). (275 aa)
LOC107086110Glyceraldehyde-3-phosphate dehydrogenase. (334 aa)
sdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (663 aa)
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (158 aa)
LOC107090538Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (175 aa)
LOC107094037Malate dehydrogenase. (333 aa)
LOC107101528Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (252 aa)
LOC107086089Enolase 2. (434 aa)
LOC107086115Triosephosphate isomerase. (268 aa)
LOC107097190Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
h6pdHexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). (790 aa)
LOC107088352ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (807 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (386 aa)
shmt2Serine hydroxymethyltransferase 2 (mitochondrial). (501 aa)
csCitrate synthase; Belongs to the citrate synthase family. (469 aa)
pccaPropionyl-CoA carboxylase subunit alpha. (624 aa)
dldDihydrolipoyl dehydrogenase. (508 aa)
me2Malic enzyme. (583 aa)
acox3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (643 aa)
LOC107081772Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (450 aa)
cps1Carbamoyl-phosphate synthase 1, mitochondrial. (1451 aa)
LOC107104202Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (482 aa)
LOC107085778Uncharacterized protein. (348 aa)
LOC107085782Uncharacterized protein. (378 aa)
LOC107082426Serine--pyruvate aminotransferase. (391 aa)
LOC107104610Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (394 aa)
LOC107091900ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
catCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
gckPhosphotransferase. (453 aa)
gpiGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
LOC107089056Phosphoribosyl pyrophosphate synthetase 1B. (318 aa)
LOC107081709Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (516 aa)
phgdhD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
LOC107081479Uncharacterized protein. (208 aa)
hadhaHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. (643 aa)
hibch3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (382 aa)
aldh6a1Aldehyde dehydrogenase 6 family member A1. (526 aa)
LOC107086791Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (528 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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