STRINGSTRING
LOC107097451 LOC107097451 atg12 atg12 LOC107086723 LOC107086723 SGK1 SGK1 LOC107102671 LOC107102671 foxo3 foxo3 cdk2 cdk2 LOC107092854 LOC107092854 CHUK CHUK LOC107104990 LOC107104990 igf1r igf1r ccnd1 ccnd1 LOC107103895 LOC107103895 mapk8 mapk8 crebbp crebbp LOC107100318 LOC107100318 gabarap gabarap prkaa2 prkaa2 LOC107086576 LOC107086576 PTEN PTEN stk11 stk11 il10 il10 LOC107101533 LOC107101533 LOC107102037 LOC107102037 PRKAB2 PRKAB2 LOC107087768 LOC107087768 sirt1 sirt1 pik3r2 pik3r2 LOC107095138 LOC107095138 map2k1 map2k1 KRAS KRAS LOC107084459 LOC107084459 prkaa1 prkaa1 sos2 sos2 il7r il7r LOC107093022 LOC107093022 tgfb2 tgfb2 LOC107100240 LOC107100240 LOC107098322 LOC107098322 LOC107095590 LOC107095590 grm1 grm1 LOC107101432 LOC107101432 hras hras LOC107089263 LOC107089263 plk3 plk3 ccnb1 ccnb1 homer3 homer3 LOC107088760 LOC107088760 bcl2l11 bcl2l11 LOC107100676 LOC107100676 grb2 grb2 HOMER2 HOMER2 pik3ca pik3ca GADD45B GADD45B LOC107087504 LOC107087504 LOC107098884 LOC107098884 LOC107091522 LOC107091522 akt1 akt1 GADD45B-2 GADD45B-2 LOC107083639 LOC107083639 Atm Atm LOC107097119 LOC107097119 braf braf bcl6 bcl6 LOC107101186 LOC107101186 CCNG2 CCNG2 LOC107096865 LOC107096865 mapk10 mapk10 LOC107094242 LOC107094242 LOC107099926 LOC107099926 map2k2 map2k2 LOC107099902 LOC107099902 sgk3 sgk3 mapk1 mapk1 LOC107095350 LOC107095350 ENSCVAP00000015734 ENSCVAP00000015734 LOC107083482 LOC107083482 LOC107088576 LOC107088576 LOC107102230 LOC107102230 LOC107102211 LOC107102211 fbxo32 fbxo32 fbxo25 fbxo25 LOC107099244 LOC107099244 s1pr1 s1pr1 cdkn2b cdkn2b LOC107088450 LOC107088450 LOC107094672 LOC107094672 LOC107083428 LOC107083428 usp7 usp7 pdpk1 pdpk1 LOC107083120 LOC107083120 TGFBR2 TGFBR2 LOC107083377 LOC107083377 stat3 stat3 LOC107089544 LOC107089544 LOC107082238 LOC107082238 prkag1 prkag1 sod2 sod2 sgk2 sgk2 LOC107092878 LOC107092878 G6PC2 G6PC2 SLC2A4 SLC2A4 GADD45A GADD45A ENSCVAP00000022050 ENSCVAP00000022050 gabarapl2 gabarapl2 LOC107091056 LOC107091056 plk4 plk4 g6pc g6pc mdm2 mdm2 skp2 skp2 smad3 smad3 LOC107086777 LOC107086777 cdkn1b cdkn1b LOC107097806 LOC107097806 LOC107081636 LOC107081636 LOC107097814 LOC107097814 SMAD3 SMAD3 ep300 ep300 LOC107096663 LOC107096663 LOC107084303 LOC107084303 LOC107091581 LOC107091581 LOC107093847 LOC107093847 plk2 plk2 klf2 klf2 LOC107099560 LOC107099560 LOC107098892 LOC107098892 rag2 rag2 rag1 rag1 LOC107101234 LOC107101234 LOC107093725 LOC107093725 ins ins LOC107085698 LOC107085698 LOC107082492 LOC107082492 igf1 igf1 irs2 irs2 ENSCVAP00000029189 ENSCVAP00000029189 ENSCVAP00000029198 ENSCVAP00000029198 LOC107085131 LOC107085131 insr insr ikbkb ikbkb foxo4 foxo4 LOC107094800 LOC107094800 PLK1 PLK1 tnfsf10 tnfsf10 cat cat ENSCVAP00000030679 ENSCVAP00000030679 cdkn2d cdkn2d LOC107102050 LOC107102050 bnip3 bnip3 egfr egfr LOC107100766 LOC107100766 ccnb3 ccnb3 LOC107094671 LOC107094671 tgfb3 tgfb3 LOC107085054 LOC107085054 setd7 setd7 LOC107085617 LOC107085617
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC107097451IlGF domain-containing protein. (190 aa)
atg12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (117 aa)
LOC107086723Mitogen-activated protein kinase. (363 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
LOC107102671Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (422 aa)
foxo3Forkhead box O3b. (666 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC107092854Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (763 aa)
LOC107104990A-Raf proto-oncogene, serine/threonine kinase. (584 aa)
igf1rTyrosine-protein kinase receptor. (1416 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
LOC107103895Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (635 aa)
mapk8Mitogen-activated protein kinase. (470 aa)
crebbpCREB binding protein b. (2380 aa)
LOC107100318Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (439 aa)
gabarapGABA(A) receptor-associated protein b. (122 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
LOC107086576Protein kinase domain-containing protein. (740 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (412 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (449 aa)
il10Interleukin 10. (184 aa)
LOC107101533Mitogen-activated protein kinase. (429 aa)
LOC107102037Uncharacterized protein. (600 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (267 aa)
LOC107087768Si:ch73-335l21.1. (1267 aa)
sirt1Sirtuin 1. (691 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (724 aa)
LOC107095138Zgc:55558. (187 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC107084459Mothers against decapentaplegic homolog. (516 aa)
prkaa1Non-specific serine/threonine protein kinase. (564 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1325 aa)
il7rFibronectin type-III domain-containing protein. (405 aa)
LOC107093022Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (351 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
LOC107100240Uncharacterized protein. (494 aa)
LOC107098322Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
LOC107095590Cyclin G2; Belongs to the cyclin family. (325 aa)
grm1Glutamate receptor, metabotropic 1a. (1158 aa)
LOC107101432Mitogen-activated protein kinase. (360 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC107089263CD40 ligand; Belongs to the tumor necrosis factor family. (240 aa)
plk3Serine/threonine-protein kinase PLK. (667 aa)
ccnb1Cyclin B1; Belongs to the cyclin family. (400 aa)
homer3Homer scaffold protein 3b. (366 aa)
LOC107088760ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1153 aa)
bcl2l11Uncharacterized protein. (242 aa)
LOC107100676Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
HOMER2Homer scaffold protein 2. (354 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1004 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
LOC107087504Mitogen-activated protein kinase. (357 aa)
LOC107098884Homer scaffold protein 1b. (358 aa)
LOC107091522Insulin receptor substrate 4a. (1343 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
GADD45B-2Growth arrest and DNA damage inducible beta. (153 aa)
LOC107083639Uncharacterized protein. (471 aa)
AtmUncharacterized protein. (145 aa)
LOC107097119Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (469 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (727 aa)
bcl6BCL6A transcription repressor a. (696 aa)
LOC107101186Mitogen-activated protein kinase. (379 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (335 aa)
LOC107096865Cyclin Dx; Belongs to the cyclin family. (304 aa)
mapk10Mitogen-activated protein kinase. (425 aa)
LOC107094242GABA type A receptor associated protein like 2. (117 aa)
LOC107099926Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC107099902Uncharacterized protein. (471 aa)
sgk3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
mapk1Mitogen-activated protein kinase. (351 aa)
LOC107095350Forkhead box O1 a. (666 aa)
ENSCVAP00000015734WH1 domain-containing protein. (226 aa)
LOC107083482Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
LOC107088576Mitogen-activated protein kinase. (364 aa)
LOC107102230Fork-head domain-containing protein. (613 aa)
LOC107102211Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
fbxo32F-box protein 32. (350 aa)
fbxo25F-box protein 25. (365 aa)
LOC107099244Fork-head domain-containing protein. (633 aa)
s1pr1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (374 aa)
cdkn2bCyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (124 aa)
LOC107088450Mothers against decapentaplegic homolog. (503 aa)
LOC107094672Ribosomal_L7Ae domain-containing protein. (159 aa)
LOC107083428CREB binding protein a. (2444 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1182 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (565 aa)
LOC107083120Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
LOC107083377Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (543 aa)
stat3Signal transducer and activator of transcription. (800 aa)
LOC107089544Casein kinase 1, epsilon; Belongs to the protein kinase superfamily. (439 aa)
LOC107082238Zgc:92606. (117 aa)
prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (334 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
sgk2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (361 aa)
LOC107092878E1A binding protein p300 a. (2648 aa)
G6PC2Glucose-6-phosphatase catalytic subunit 2. (358 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (505 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (162 aa)
ENSCVAP00000022050CBS domain-containing protein. (115 aa)
gabarapl2GABA(A) receptor-associated protein like 2. (116 aa)
LOC107091056AMPKBI domain-containing protein. (269 aa)
plk4Polo-like kinase 4 (Drosophila). (913 aa)
g6pcGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (354 aa)
mdm2MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (482 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (409 aa)
smad3Mothers against decapentaplegic homolog. (425 aa)
LOC107086777Insulin receptor substrate 2a. (1061 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (202 aa)
LOC107097806Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (265 aa)
LOC107081636Uncharacterized protein; Belongs to the protein kinase superfamily. (417 aa)
LOC107097814Uncharacterized protein. (718 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ep300E1A binding protein p300 b. (2766 aa)
LOC107096663Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
LOC107084303Cyclin D2, a; Belongs to the cyclin family. (296 aa)
LOC107091581Glutamate receptor, metabotropic 1b. (1162 aa)
LOC107093847Growth arrest and DNA-damage-inducible, gamma a. (159 aa)
plk2Serine/threonine-protein kinase PLK. (657 aa)
klf2Kruppel-like factor 2b. (383 aa)
LOC107099560Uncharacterized protein. (164 aa)
LOC107098892Receptor protein-tyrosine kinase. (1168 aa)
rag2Recombination activating gene 2. (533 aa)
rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1104 aa)
LOC107101234Fork-head domain-containing protein. (392 aa)
LOC107093725Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (336 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (140 aa)
LOC107085698Cyclin D2, b; Belongs to the cyclin family. (304 aa)
LOC107082492Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
igf1Insulin-like growth factor 1. (186 aa)
irs2Insulin receptor substrate 2b. (1114 aa)
ENSCVAP00000029189Forkhead box O6 b. (604 aa)
ENSCVAP00000029198V-akt murine thymoma viral oncogene homolog 3b. (181 aa)
LOC107085131Forkhead box O6 a. (719 aa)
insrTyrosine-protein kinase receptor. (1362 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (710 aa)
foxo4Forkhead box O4. (639 aa)
LOC107094800Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (437 aa)
PLK1Serine/threonine-protein kinase PLK. (582 aa)
tnfsf10TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (279 aa)
catCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
ENSCVAP00000030679IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (48 aa)
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
LOC107102050Mitogen-activated protein kinase. (420 aa)
bnip3BCL2 interacting protein 3. (191 aa)
egfrReceptor protein-tyrosine kinase. (1205 aa)
LOC107100766Sphingosine-1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family. (414 aa)
ccnb3Cyclin B3; Belongs to the cyclin family. (430 aa)
LOC107094671Growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1. (154 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (400 aa)
LOC107085054Cyclin B2; Belongs to the cyclin family. (390 aa)
setd7SET domain containing 7, histone lysine methyltransferase. (382 aa)
LOC107085617Cyclin-dependent kinase inhibitor 1A. (168 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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