STRINGSTRING
LOC107099974 LOC107099974 LOC107100187 LOC107100187 atg12 atg12 atg10 atg10 tank tank rab8a rab8a LOC107092854 LOC107092854 igf1r igf1r prkacb prkacb eif2ak3 eif2ak3 ern1 ern1 atg4d atg4d LOC107087164 LOC107087164 mapk8 mapk8 LOC107091098 LOC107091098 wipi2 wipi2 gabarap gabarap prkaa2 prkaa2 PTEN PTEN ENSCVAP00000003563 ENSCVAP00000003563 stk11 stk11 LOC107101533 LOC107101533 lamp2 lamp2 prkcd prkcd rab7a rab7a LOC107087768 LOC107087768 LOC107086509 LOC107086509 pik3r2 pik3r2 LOC107095138 LOC107095138 map2k1 map2k1 KRAS KRAS prkaa1 prkaa1 rb1cc1 rb1cc1 LOC107094496 LOC107094496 LOC107090031 LOC107090031 rptor rptor ZFYVE1 ZFYVE1 mras mras nrbf2 nrbf2 hras hras lamp1 lamp1 stx17 stx17 LOC107093905 LOC107093905 LOC107093106 LOC107093106 supt20h supt20h LOC107102478 LOC107102478 hif1a hif1a LOC107092135 LOC107092135 pik3ca pik3ca LOC107085938 LOC107085938 LOC107097676 LOC107097676 LOC107092109 LOC107092109 LOC107090965 LOC107090965 atg4c atg4c LOC107091522 LOC107091522 ulk1 ulk1 akt1 akt1 LOC107083639 LOC107083639 LOC107085894 LOC107085894 igbp1 igbp1 LOC107088138 LOC107088138 LOC107097085 LOC107097085 ctsl ctsl LOC107096319 LOC107096319 MTMR4 MTMR4 rubcn rubcn LOC107087452 LOC107087452 RAB39B RAB39B LOC107100418 LOC107100418 LOC107088057 LOC107088057 LOC107099463 LOC107099463 LOC107101186 LOC107101186 LOC107086406 LOC107086406 traf6 traf6 LOC107096503 LOC107096503 LOC107096509 LOC107096509 mapk10 mapk10 bad bad LOC107094242 LOC107094242 LOC107099926 LOC107099926 atg16l1 atg16l1 map2k2 map2k2 c9orf72 c9orf72 LOC107084657 LOC107084657 LOC107094261 LOC107094261 LOC107099902 LOC107099902 LOC107080667 LOC107080667 rragc rragc mapk1 mapk1 LOC107100460 LOC107100460 LOC107083482 LOC107083482 EIF2AK4 EIF2AK4 snap29 snap29 atg5 atg5 LOC107100436 LOC107100436 LOC107102211 LOC107102211 deptor deptor LOC107102182 LOC107102182 WIPI1 WIPI1 tbk1 tbk1 atg101 atg101 uvrag uvrag becn1 becn1 mlst8 mlst8 atg3 atg3 LOC107099236 LOC107099236 pdpk1 pdpk1 smcr8 smcr8 ATG2B ATG2B LOC107083382 LOC107083382 ENSCVAP00000019550 ENSCVAP00000019550 LOC107093417 LOC107093417 LOC107093251 LOC107093251 LOC107100231 LOC107100231 LOC107082238 LOC107082238 rhebl1 rhebl1 camkk2 camkk2 prkcq prkcq mtor mtor ENSCVAP00000020262 ENSCVAP00000020262 eif2s1 eif2s1 atg9a atg9a rheb rheb gabarapl2 gabarapl2 sqstm1 sqstm1 ddit4 ddit4 atg2a atg2a LOC107087654 LOC107087654 LOC107086777 LOC107086777 prkaca prkaca LOC107097814 LOC107097814 LOC107091612 LOC107091612 atg14 atg14 LOC107080941 LOC107080941 wdr41 wdr41 dapk1 dapk1 LOC107099482 LOC107099482 LOC107096336 LOC107096336 VMP1 VMP1 pik3c3 pik3c3 ins ins LOC107091979 LOC107091979 LOC107096502 LOC107096502 akt1s1 akt1s1 irs2 irs2 ENSCVAP00000029198 ENSCVAP00000029198 ambra1 ambra1 mtmr3 mtmr3 LOC107102465 LOC107102465 LOC107099893 LOC107099893 dapk3 dapk3 LOC107094800 LOC107094800 ENSCVAP00000030679 ENSCVAP00000030679 LOC107082357 LOC107082357 LOC107092506 LOC107092506 LOC107097523 LOC107097523 LOC107102050 LOC107102050 bnip3 bnip3 zfyve1 zfyve1 LOC107087875 LOC107087875 ctsb ctsb LOC107096935 LOC107096935 LOC107085055 LOC107085055 LOC107096932 LOC107096932
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC107099974BH4_2 domain-containing protein. (219 aa)
LOC107100187Si:dkeyp-97e7.9. (403 aa)
atg12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (117 aa)
atg10Autophagy_act_C domain-containing protein. (227 aa)
tankTRAF family member-associated NFKB activator. (335 aa)
rab8aRAB8A, member RAS oncogene family. (206 aa)
LOC107092854Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
igf1rTyrosine-protein kinase receptor. (1416 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1100 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (1063 aa)
atg4dCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (497 aa)
LOC107087164Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (397 aa)
mapk8Mitogen-activated protein kinase. (470 aa)
LOC107091098Cathepsin D; Belongs to the peptidase A1 family. (396 aa)
wipi2WD repeat domain, phosphoinositide interacting 2. (427 aa)
gabarapGABA(A) receptor-associated protein b. (122 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (412 aa)
ENSCVAP00000003563Si:dkey-240h12.4. (154 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (449 aa)
LOC107101533Mitogen-activated protein kinase. (429 aa)
lamp2Lysosomal-associated membrane protein 2. (433 aa)
prkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
rab7aUncharacterized protein. (207 aa)
LOC107087768Si:ch73-335l21.1. (1267 aa)
LOC107086509Vesicle-associated membrane protein 8 (endobrevin). (124 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (724 aa)
LOC107095138Zgc:55558. (187 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
prkaa1Non-specific serine/threonine protein kinase. (564 aa)
rb1cc1RB1-inducible coiled-coil 1. (1612 aa)
LOC107094496Si:ch211-11n16.2. (655 aa)
LOC107090031Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1373 aa)
ZFYVE1Uncharacterized protein. (621 aa)
mrasMuscle RAS oncogene homolog. (208 aa)
nrbf2Nuclear receptor binding factor 2b. (269 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
lamp1Lysosomal associated membrane protein 1a. (424 aa)
stx17Syntaxin 17; Belongs to the syntaxin family. (297 aa)
LOC107093905RAB7a, member RAS oncogene family. (207 aa)
LOC107093106Smith-Magenis syndrome chromosome region, candidate 8a. (953 aa)
supt20hSPT20 homolog, SAGA complex component. (833 aa)
LOC107102478BH4_2 domain-containing protein. (226 aa)
hif1aHypoxia inducible factor 1 subunit alpha a. (752 aa)
LOC107092135Cathepsin Ba; Belongs to the peptidase C1 family. (335 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1004 aa)
LOC107085938RAB8A, member RAS oncogene family. (206 aa)
LOC107097676SH3-domain GRB2-like endophilin B1a. (364 aa)
LOC107092109High mobility group box 1b. (199 aa)
LOC107090965Unc-51 like autophagy activating kinase 1. (1024 aa)
atg4cCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (475 aa)
LOC107091522Insulin receptor substrate 4a. (1343 aa)
ulk1Unc-51 like autophagy activating kinase 1a. (785 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
LOC107083639Uncharacterized protein. (471 aa)
LOC107085894Serine/threonine-protein phosphatase. (309 aa)
igbp1Immunoglobulin (CD79A) binding protein 1. (354 aa)
LOC107088138High mobility group box 1a. (201 aa)
LOC107097085Uncharacterized protein. (725 aa)
ctslUncharacterized protein; Belongs to the peptidase C1 family. (337 aa)
LOC107096319Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (498 aa)
MTMR4Myotubularin related protein 4. (1202 aa)
rubcnRubicon autophagy regulator. (951 aa)
LOC107087452Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (509 aa)
RAB39BRAB39B, member RAS oncogene family. (213 aa)
LOC107100418Uncharacterized protein. (223 aa)
LOC107088057Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
LOC107099463Cathepsin 12; Belongs to the peptidase C1 family. (353 aa)
LOC107101186Mitogen-activated protein kinase. (379 aa)
LOC107086406Endoplasmic reticulum to nucleus signaling 2. (973 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)
LOC107096503Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa)
LOC107096509Uncharacterized protein; Belongs to the peptidase C1 family. (337 aa)
mapk10Mitogen-activated protein kinase. (425 aa)
badBCL2 associated agonist of cell death b. (163 aa)
LOC107094242GABA type A receptor associated protein like 2. (117 aa)
LOC107099926Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
atg16l1ATG16 autophagy related 16-like 1 (S. cerevisiae). (604 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
c9orf72Zgc:100846. (462 aa)
LOC107084657Serine/threonine-protein phosphatase. (309 aa)
LOC107094261Uncharacterized protein. (375 aa)
LOC107099902Uncharacterized protein. (471 aa)
LOC107080667Uncharacterized protein. (202 aa)
rragcRas-related GTP binding Ca. (382 aa)
mapk1Mitogen-activated protein kinase. (351 aa)
LOC107100460Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (807 aa)
LOC107083482Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1654 aa)
snap29Synaptosome associated protein 29. (260 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
LOC107100436Zgc:101559. (234 aa)
LOC107102211Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
deptorDEP domain containing MTOR-interacting protein. (320 aa)
LOC107102182Si:ch73-234b20.5. (103 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (445 aa)
tbk1TANK-binding kinase 1. (720 aa)
atg101Autophagy related 101. (215 aa)
uvragUV radiation resistance associated gene. (729 aa)
becn1Beclin 1, autophagy related. (448 aa)
mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (260 aa)
atg3Autophagy-related protein 3. (316 aa)
LOC107099236Death-associated protein kinase 2b; Belongs to the protein kinase superfamily. (363 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (565 aa)
smcr8UDENN FLCN/SMCR8-type domain-containing protein. (897 aa)
ATG2BAutophagy related 2B. (1624 aa)
LOC107083382BCL2 apoptosis regulator b. (227 aa)
ENSCVAP00000019550RAB33B, member RAS oncogene family a. (206 aa)
LOC107093417Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
LOC107093251Uncharacterized protein. (241 aa)
LOC107100231Si:dkey-13a21.4. (204 aa)
LOC107082238Zgc:92606. (117 aa)
rhebl1Ras homolog, mTORC1 binding like 1. (184 aa)
camkk2Si:ch73-62l21.1. (571 aa)
prkcqProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (719 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2406 aa)
ENSCVAP00000020262MIR domain-containing protein. (209 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
atg9aAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (851 aa)
rhebUncharacterized protein. (183 aa)
gabarapl2GABA(A) receptor-associated protein like 2. (116 aa)
sqstm1Sequestosome 1. (435 aa)
ddit4DNA-damage-inducible transcript 4. (225 aa)
atg2aAutophagy related 2A. (1988 aa)
LOC107087654Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (463 aa)
LOC107086777Insulin receptor substrate 2a. (1061 aa)
prkacaUncharacterized protein; Belongs to the protein kinase superfamily. (382 aa)
LOC107097814Uncharacterized protein. (718 aa)
LOC107091612Zgc:171927. (214 aa)
atg14Autophagy related 14. (501 aa)
LOC107080941Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
wdr41WD repeat domain 41. (368 aa)
dapk1Death-associated protein kinase 1. (1445 aa)
LOC107099482Si:dkey-26g8.5; Belongs to the peptidase C1 family. (336 aa)
LOC107096336Vacuole membrane protein 1. (402 aa)
VMP1Vacuole membrane protein 1. (486 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (885 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (140 aa)
LOC107091979Uncharacterized protein. (213 aa)
LOC107096502Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa)
akt1s1AKT1 substrate 1 (proline-rich). (350 aa)
irs2Insulin receptor substrate 2b. (1114 aa)
ENSCVAP00000029198V-akt murine thymoma viral oncogene homolog 3b. (181 aa)
ambra1Autophagy/beclin-1 regulator 1b. (1374 aa)
mtmr3Myotubularin phosphatase domain-containing protein. (450 aa)
LOC107102465TSC complex subunit 1b. (1258 aa)
LOC107099893Lysosomal associated membrane protein 1. (255 aa)
dapk3Death-associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
LOC107094800Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (437 aa)
ENSCVAP00000030679IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (48 aa)
LOC107082357Inositol 1,4,5-trisphosphate receptor, type 1b. (2672 aa)
LOC107092506Hypoxia inducible factor 1 subunit alpha, like. (660 aa)
LOC107097523Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (484 aa)
LOC107102050Mitogen-activated protein kinase. (420 aa)
bnip3BCL2 interacting protein 3. (191 aa)
zfyve1Zinc finger, FYVE domain containing 1. (774 aa)
LOC107087875Ras-related GTP binding A. (315 aa)
ctsbCathepsin Bb; Belongs to the peptidase C1 family. (337 aa)
LOC107096935Uncharacterized protein. (205 aa)
LOC107085055Death-associated protein kinase 2a; Belongs to the protein kinase superfamily. (494 aa)
LOC107096932RAB1A, member RAS oncogene family a. (202 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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