STRINGSTRING
LOC107099974 LOC107099974 tnfrsf1a tnfrsf1a casp2 casp2 Itpr3 Itpr3 LOC107098580 LOC107098580 CTSO CTSO LOC107092852 LOC107092852 LOC107092854 LOC107092854 CHUK CHUK LOC107092860 LOC107092860 LOC107082027 LOC107082027 nfkbia nfkbia eif2ak3 eif2ak3 ern1 ern1 il4r il4r LOC107087164 LOC107087164 mapk8 mapk8 LOC107091098 LOC107091098 actb actb LOC107086576 LOC107086576 LOC107096158 LOC107096158 LOC107101533 LOC107101533 parp2 parp2 tuba4a tuba4a LOC107090074 LOC107090074 pik3r2 pik3r2 LOC107095138 LOC107095138 map2k1 map2k1 KRAS KRAS LOC107088362 LOC107088362 CAPN2 CAPN2 ENSCVAP00000005712 ENSCVAP00000005712 Sptan1 Sptan1 LOC107095079 LOC107095079 nfkb1 nfkb1 hras hras CTSZ CTSZ LOC107089263 LOC107089263 ddit3 ddit3 LOC107087023 LOC107087023 LOC107090480 LOC107090480 endog endog LOC107102478 LOC107102478 LOC107087576 LOC107087576 LOC107092135 LOC107092135 LOC107098032 LOC107098032 ENSCVAP00000009065 ENSCVAP00000009065 bcl2l11 bcl2l11 LOC107101302 LOC107101302 pik3ca pik3ca LOC107095483 LOC107095483 LOC107084770 LOC107084770 LOC107084771 LOC107084771 LOC107099539 LOC107099539 dffb dffb apaf1 apaf1 LOC107095469 LOC107095469 GADD45B GADD45B LOC107093789 LOC107093789 LOC107101802 LOC107101802 lmnb2 lmnb2 LOC107089173 LOC107089173 akt1 akt1 GADD45B-2 GADD45B-2 LOC107084720 LOC107084720 LOC107083639 LOC107083639 Jun Jun LOC107101768 LOC107101768 ctsl ctsl LOC107095424 LOC107095424 Atm Atm dab2ip dab2ip lmnb1 lmnb1 LOC107104260 LOC107104260 LOC107088057 LOC107088057 LOC107099463 LOC107099463 LOC107101186 LOC107101186 LOC107086406 LOC107086406 LOC107088035 LOC107088035 LOC107088039 LOC107088039 LOC107096503 LOC107096503 LOC107096509 LOC107096509 LOC107095977 LOC107095977 mapk10 mapk10 aifm1 aifm1 bad bad dffa dffa LOC107099926 LOC107099926 LOC107102261 LOC107102261 traf2 traf2 LOC107090817 LOC107090817 LOC107102257 LOC107102257 map2k2 map2k2 LOC107084615 LOC107084615 LOC107099902 LOC107099902 LOC107080667 LOC107080667 ctsc ctsc mapk1 mapk1 LOC107083482 LOC107083482 LOC107086772 LOC107086772 LOC107086845 LOC107086845 LOC107102211 LOC107102211 LOC107096398 LOC107096398 LOC107086824 LOC107086824 ENSCVAP00000017074 ENSCVAP00000017074 ctsw ctsw LOC107086239 LOC107086239 casp7 casp7 LOC107095300 LOC107095300 LOC107086758 LOC107086758 LOC107094672 LOC107094672 pdpk1 pdpk1 LOC107083128 LOC107083128 LOC107083139 LOC107083139 LOC107083382 LOC107083382 parp3 parp3 ENSCVAP00000020262 ENSCVAP00000020262 LOC107094654 LOC107094654 casp6 casp6 birc2 birc2 LOC107082055 LOC107082055 atf4 atf4 LOC107103873 LOC107103873 eif2s1 eif2s1 GADD45A GADD45A tp53 tp53 tradd tradd LOC107088360 LOC107088360 LOC107098347 LOC107098347 itpr2 itpr2 LOC107093973 LOC107093973 LOC107085476 LOC107085476 LOC107085484 LOC107085484 LOC107082647 LOC107082647 LOC107081311 LOC107081311 LOC107097814 LOC107097814 LOC107084350 LOC107084350 LOC107103707 LOC107103707 LOC107088747 LOC107088747 LOC107093847 LOC107093847 LOC107080941 LOC107080941 casp9 casp9 BAX BAX LOC107099482 LOC107099482 LOC107104273 LOC107104273 LOC107086463 LOC107086463 LOC107096502 LOC107096502 ENSCVAP00000029198 ENSCVAP00000029198 LOC107102256 LOC107102256 ctsh ctsh LOC107090059 LOC107090059 ikbkb ikbkb LOC107099875 LOC107099875 LOC107084596 LOC107084596 tnfsf10 tnfsf10 LOC107082357 LOC107082357 lmna lmna LOC107102050 LOC107102050 ntrk1 ntrk1 parp1 parp1 map3k5 map3k5 LOC107103992 LOC107103992 LOC107094671 LOC107094671 ctsb ctsb LOC107092405 LOC107092405 LOC107101578 LOC107101578 rela rela
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC107099974BH4_2 domain-containing protein. (219 aa)
tnfrsf1aTumor necrosis factor receptor superfamily, member 1a. (383 aa)
casp2Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (460 aa)
Itpr3Ion_trans domain-containing protein. (468 aa)
LOC107098580Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (406 aa)
CTSOCathepsin O; Belongs to the peptidase C1 family. (327 aa)
LOC107092852Tumor necrosis factor receptor superfamily, member a. (308 aa)
LOC107092854Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (763 aa)
LOC107092860TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (597 aa)
LOC107082027Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (106 aa)
nfkbiaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (319 aa)
eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1100 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (1063 aa)
il4rUncharacterized protein. (701 aa)
LOC107087164Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (397 aa)
mapk8Mitogen-activated protein kinase. (470 aa)
LOC107091098Cathepsin D; Belongs to the peptidase A1 family. (396 aa)
actbUncharacterized protein. (375 aa)
LOC107086576Protein kinase domain-containing protein. (740 aa)
LOC107096158P53-induced death domain protein 1. (918 aa)
LOC107101533Mitogen-activated protein kinase. (429 aa)
parp2Poly [ADP-ribose] polymerase. (615 aa)
tuba4aTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (458 aa)
LOC107090074Activating transcription factor 4a. (439 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (724 aa)
LOC107095138Zgc:55558. (187 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC107088362Cathepsin S, ortholog 1; Belongs to the peptidase C1 family. (331 aa)
CAPN2Calpain 2, (m/II) large subunit, like; Belongs to the peptidase C2 family. (701 aa)
ENSCVAP00000005712Uncharacterized protein. (94 aa)
Sptan1Uncharacterized protein. (178 aa)
LOC107095079Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
nfkb1Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (893 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (297 aa)
LOC107089263CD40 ligand; Belongs to the tumor necrosis factor family. (240 aa)
ddit3DNA-damage-inducible transcript 3. (309 aa)
LOC107087023Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (287 aa)
LOC107090480Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (281 aa)
endogEndonuclease. (295 aa)
LOC107102478BH4_2 domain-containing protein. (226 aa)
LOC107087576Si:dkey-33c12.12. (448 aa)
LOC107092135Cathepsin Ba; Belongs to the peptidase C1 family. (335 aa)
LOC107098032Perforin 1.5. (523 aa)
ENSCVAP00000009065Tubulin domain-containing protein. (81 aa)
bcl2l11Uncharacterized protein. (242 aa)
LOC107101302Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (197 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1004 aa)
LOC107095483Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (304 aa)
LOC107084770Uncharacterized protein. (582 aa)
LOC107084771Uncharacterized protein. (584 aa)
LOC107099539Diablo, IAP-binding mitochondrial protein a. (268 aa)
dffbDNA fragmentation factor, beta polypeptide (caspase-activated DNase). (345 aa)
apaf1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1256 aa)
LOC107095469Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (239 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
LOC107093789Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (580 aa)
LOC107101802MACPF domain-containing protein. (516 aa)
lmnb2Lamin B2; Belongs to the intermediate filament family. (577 aa)
LOC107089173Cathepsin Z; Belongs to the peptidase C1 family. (313 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
GADD45B-2Growth arrest and DNA damage inducible beta. (153 aa)
LOC107084720Mitogen-activated protein kinase kinase kinase 14a. (873 aa)
LOC107083639Uncharacterized protein. (471 aa)
JunBZIP domain-containing protein; Belongs to the bZIP family. (310 aa)
LOC107101768Uncharacterized protein. (196 aa)
ctslUncharacterized protein; Belongs to the peptidase C1 family. (337 aa)
LOC107095424Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (308 aa)
AtmUncharacterized protein. (145 aa)
dab2ipDAB2 interacting protein b. (1185 aa)
lmnb1Lamin B1; Belongs to the intermediate filament family. (578 aa)
LOC107104260Uncharacterized protein. (1167 aa)
LOC107088057Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
LOC107099463Cathepsin 12; Belongs to the peptidase C1 family. (353 aa)
LOC107101186Mitogen-activated protein kinase. (379 aa)
LOC107086406Endoplasmic reticulum to nucleus signaling 2. (973 aa)
LOC107088035Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
LOC107088039Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC107096503Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa)
LOC107096509Uncharacterized protein; Belongs to the peptidase C1 family. (337 aa)
LOC107095977Cytochrome c, somatic b; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
mapk10Mitogen-activated protein kinase. (425 aa)
aifm1Apoptosis inducing factor mitochondrion associated 1. (640 aa)
badBCL2 associated agonist of cell death b. (163 aa)
dffaDNA fragmentation factor, alpha polypeptide. (295 aa)
LOC107099926Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC107102261Calpain 1, (mu/I) large subunit a; Belongs to the peptidase C2 family. (704 aa)
traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (515 aa)
LOC107090817Uncharacterized protein; Belongs to the intermediate filament family. (643 aa)
LOC107102257Uncharacterized protein; Belongs to the peptidase C2 family. (683 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC107084615Si:ch211-1i11.3. (1329 aa)
LOC107099902Uncharacterized protein. (471 aa)
LOC107080667Uncharacterized protein. (202 aa)
ctscCathepsin C; Belongs to the peptidase C1 family. (455 aa)
mapk1Mitogen-activated protein kinase. (351 aa)
LOC107083482Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
LOC107086772Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family. (337 aa)
LOC107086845Cathepsin K; Belongs to the peptidase C1 family. (334 aa)
LOC107102211Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC107096398Uncharacterized protein; Belongs to the peptidase C14A family. (273 aa)
LOC107086824Uncharacterized protein; Belongs to the peptidase C14A family. (477 aa)
ENSCVAP00000017074TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (64 aa)
ctswCathepsin F; Belongs to the peptidase C1 family. (471 aa)
LOC107086239Uncharacterized protein; Belongs to the peptidase C2 family. (693 aa)
casp7Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (325 aa)
LOC107095300Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
LOC107086758Baculoviral IAP repeat containing 5b. (148 aa)
LOC107094672Ribosomal_L7Ae domain-containing protein. (159 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (565 aa)
LOC107083128Si:ch211-153j24.3. (375 aa)
LOC107083139V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (363 aa)
LOC107083382BCL2 apoptosis regulator b. (227 aa)
parp3Poly [ADP-ribose] polymerase. (525 aa)
ENSCVAP00000020262MIR domain-containing protein. (209 aa)
LOC107094654Uncharacterized protein. (445 aa)
casp6Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (293 aa)
birc2Baculoviral IAP repeat containing 2. (615 aa)
LOC107082055Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (499 aa)
atf4Activating transcription factor 4b. (442 aa)
LOC107103873Zgc:55262; Belongs to the peptidase C2 family. (706 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (162 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (351 aa)
traddTnfrsf1a-associated via death domain. (292 aa)
LOC107088360Uncharacterized protein; Belongs to the peptidase C1 family. (339 aa)
LOC107098347Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (477 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2625 aa)
LOC107093973ADP-ribosylation factor 2b. (934 aa)
LOC107085476Uncharacterized protein. (471 aa)
LOC107085484Uncharacterized protein. (553 aa)
LOC107082647Calpain 2, (m/II) large subunit b; Belongs to the peptidase C2 family. (659 aa)
LOC107081311Uncharacterized protein. (198 aa)
LOC107097814Uncharacterized protein. (718 aa)
LOC107084350Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC107103707Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (251 aa)
LOC107088747Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC107093847Growth arrest and DNA-damage-inducible, gamma a. (159 aa)
LOC107080941Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
casp9Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (430 aa)
BAXBCL2 associated X, apoptosis regulator. (191 aa)
LOC107099482Si:dkey-26g8.5; Belongs to the peptidase C1 family. (336 aa)
LOC107104273Uncharacterized protein. (373 aa)
LOC107086463Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC107096502Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa)
ENSCVAP00000029198V-akt murine thymoma viral oncogene homolog 3b. (181 aa)
LOC107102256Uncharacterized protein; Belongs to the peptidase C2 family. (712 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (325 aa)
LOC107090059Diablo, IAP-binding mitochondrial protein a. (250 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (710 aa)
LOC107099875Baculoviral IAP repeat containing 5a. (142 aa)
LOC107084596MCL1 apoptosis regulator, BCL2 family member b. (264 aa)
tnfsf10TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (279 aa)
LOC107082357Inositol 1,4,5-trisphosphate receptor, type 1b. (2672 aa)
lmnaLamin A; Belongs to the intermediate filament family. (637 aa)
LOC107102050Mitogen-activated protein kinase. (420 aa)
ntrk1Tyrosine-protein kinase receptor. (609 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (979 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1356 aa)
LOC107103992Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (449 aa)
LOC107094671Growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1. (154 aa)
ctsbCathepsin Bb; Belongs to the peptidase C1 family. (337 aa)
LOC107092405V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (367 aa)
LOC107101578Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
relaV-rel avian reticuloendotheliosis viral oncogene homolog A. (622 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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