STRINGSTRING
LOC107093432 LOC107093432 ENSCVAP00000000359 ENSCVAP00000000359 LOC107086728 LOC107086728 Itpr3 Itpr3 LOC107086723 LOC107086723 ENSCVAP00000000534 ENSCVAP00000000534 foxo3 foxo3 cdk4 cdk4 LOC107105075 LOC107105075 cdk2 cdk2 LOC107092854 LOC107092854 smad2 smad2 LOC107095771 LOC107095771 ccnd1 ccnd1 rbl1 rbl1 trpv4 trpv4 PTEN PTEN RASSF5 RASSF5 sirt1 sirt1 pik3r2 pik3r2 LOC107095138 LOC107095138 map2k1 map2k1 KRAS KRAS tgfb2 tgfb2 CAPN2 CAPN2 ENSCVAP00000005712 ENSCVAP00000005712 nfkb1 nfkb1 LOC107098322 LOC107098322 LOC107101432 LOC107101432 mras mras E2F3 E2F3 hras hras LOC107089923 LOC107089923 myc myc ppp3r1 ppp3r1 ccnb1 ccnb1 slc25a4 slc25a4 serpine1 serpine1 LOC107100676 LOC107100676 LOC107104349 LOC107104349 pik3ca pik3ca calm1 calm1 MAP2K6 MAP2K6 GADD45B GADD45B LOC107087504 LOC107087504 ENSCVAP00000010702 ENSCVAP00000010702 ENSCVAP00000010842 ENSCVAP00000010842 akt1 akt1 Lin52 Lin52 GADD45B-2 GADD45B-2 vdac1 vdac1 LOC107083639 LOC107083639 Atm Atm rb1 rb1 hipk2 hipk2 ENSCVAP00000012118 ENSCVAP00000012118 LOC107080775 LOC107080775 e2f2 e2f2 LOC107101186 LOC107101186 LOC107098778 LOC107098778 LOC107096865 LOC107096865 LOC107084148 LOC107084148 ENSCVAP00000013785 ENSCVAP00000013785 LOC107090247 LOC107090247 foxm1 foxm1 LOC107099926 LOC107099926 ppp1cc ppp1cc LOC107102261 LOC107102261 LOC107102257 LOC107102257 LOC107083028 LOC107083028 map2k2 map2k2 LOC107099902 LOC107099902 mapk1 mapk1 SLC25A6 SLC25A6 LOC107095350 LOC107095350 LOC107091913 LOC107091913 LOC107083482 LOC107083482 LOC107088576 LOC107088576 LOC107102230 LOC107102230 LOC107082405 LOC107082405 LOC107102211 LOC107102211 ccne2 ccne2 ets1 ets1 zfp36l2 zfp36l2 LOC107102162 LOC107102162 calml4 calml4 LOC107086239 LOC107086239 lin9 lin9 cdk1 cdk1 LOC107099244 LOC107099244 cdkn2b cdkn2b LOC107089590 LOC107089590 LOC107089589 LOC107089589 IGFBP3 IGFBP3 LOC107099230 LOC107099230 LOC107098654 LOC107098654 LOC107094672 LOC107094672 gata4 gata4 VDAC2 VDAC2 LOC107083120 LOC107083120 LOC107096927 LOC107096927 TGFBR2 TGFBR2 ccnd3 ccnd3 LOC107082804 LOC107082804 rhebl1 rhebl1 mtor mtor ENSCVAP00000020262 ENSCVAP00000020262 nbn nbn ENSCVAP00000020525 ENSCVAP00000020525 LOC107103873 LOC107103873 rheb rheb nfatc3 nfatc3 GADD45A GADD45A sqstm1 sqstm1 ppid ppid tp53 tp53 lin37 lin37 LOC107100856 LOC107100856 LOC107086084 LOC107086084 itpr2 itpr2 ENSCVAP00000023403 ENSCVAP00000023403 mdm2 mdm2 LOC107082647 LOC107082647 smad3 smad3 zfp36l1 zfp36l1 LOC107097814 LOC107097814 SLC25A5 SLC25A5 LOC107091641 LOC107091641 SMAD3 SMAD3 hus1 hus1 LOC107103682 LOC107103682 LOC107084303 LOC107084303 e2f4 e2f4 nfatc2 nfatc2 LOC107093847 LOC107093847 ENSCVAP00000026364 ENSCVAP00000026364 rbbp4 rbbp4 LOC107097099 LOC107097099 LOC107099516 LOC107099516 LOC107090959 LOC107090959 LOC107084790 LOC107084790 ccna2 ccna2 LOC107089823 LOC107089823 LOC107085244 LOC107085244 rad50 rad50 ccna1 ccna1 cdk6 cdk6 LOC107085698 LOC107085698 LOC107082492 LOC107082492 LOC107094299 LOC107094299 LOC107096949 LOC107096949 ENSCVAP00000029189 ENSCVAP00000029189 ENSCVAP00000029198 ENSCVAP00000029198 ENSCVAP00000029286 ENSCVAP00000029286 rad1 rad1 LOC107102256 LOC107102256 LOC107102465 LOC107102465 mre11 mre11 LOC107094800 LOC107094800 LOC107082357 LOC107082357 LOC107085709 LOC107085709 hipk3 hipk3 rad9a rad9a ccnb3 ccnb3 LOC107094671 LOC107094671 tgfb3 tgfb3 LOC107085054 LOC107085054 LOC107100954 LOC107100954 ppp1cb ppp1cb LOC107085617 LOC107085617 rela rela
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC107093432Myelocytomatosis oncogene homolog. (361 aa)
ENSCVAP00000000359Ig-like domain-containing protein; Belongs to the MHC class I family. (334 aa)
LOC107086728Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa)
Itpr3Ion_trans domain-containing protein. (468 aa)
LOC107086723Mitogen-activated protein kinase. (363 aa)
ENSCVAP00000000534Glutathione S-transferase theta 2; Belongs to the GST superfamily. (212 aa)
foxo3Forkhead box O3b. (666 aa)
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (306 aa)
LOC107105075E2F_TDP domain-containing protein. (311 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC107092854Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
smad2Mothers against decapentaplegic homolog. (474 aa)
LOC107095771TRAF3 interacting protein 2-like. (439 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
rbl1Retinoblastoma-like 1 (p107). (925 aa)
trpv4Transient receptor potential cation channel, subfamily V, member 4; Belongs to the transient receptor (TC 1.A.4) family. (883 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (412 aa)
RASSF5Ras association domain family member 5. (270 aa)
sirt1Sirtuin 1. (691 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (724 aa)
LOC107095138Zgc:55558. (187 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
CAPN2Calpain 2, (m/II) large subunit, like; Belongs to the peptidase C2 family. (701 aa)
ENSCVAP00000005712Uncharacterized protein. (94 aa)
nfkb1Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (893 aa)
LOC107098322Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
LOC107101432Mitogen-activated protein kinase. (360 aa)
mrasMuscle RAS oncogene homolog. (208 aa)
E2F3E2F transcription factor 3. (442 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC107089923RHD domain-containing protein. (689 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (426 aa)
ppp3r1Uncharacterized protein. (170 aa)
ccnb1Cyclin B1; Belongs to the cyclin family. (400 aa)
slc25a4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (299 aa)
serpine1Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (435 aa)
LOC107100676Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
LOC107104349Serine/threonine-protein phosphatase. (493 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1004 aa)
calm1Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
MAP2K6Mitogen-activated protein kinase kinase 6. (335 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
LOC107087504Mitogen-activated protein kinase. (357 aa)
ENSCVAP00000010702Ig-like domain-containing protein; Belongs to the MHC class I family. (317 aa)
ENSCVAP00000010842E2F_TDP domain-containing protein. (109 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
Lin52Lin-52 DREAM MuvB core complex component. (105 aa)
GADD45B-2Growth arrest and DNA damage inducible beta. (153 aa)
vdac1Voltage-dependent anion channel 1. (283 aa)
LOC107083639Uncharacterized protein. (471 aa)
AtmUncharacterized protein. (145 aa)
rb1Retinoblastoma 1. (912 aa)
hipk2Homeodomain interacting protein kinase 2. (1237 aa)
ENSCVAP00000012118E2F_TDP domain-containing protein. (76 aa)
LOC107080775Ig-like domain-containing protein; Belongs to the MHC class I family. (354 aa)
e2f2Si:ch211-160f23.5. (444 aa)
LOC107101186Mitogen-activated protein kinase. (379 aa)
LOC107098778Mothers against decapentaplegic homolog. (466 aa)
LOC107096865Cyclin Dx; Belongs to the cyclin family. (304 aa)
LOC107084148Serine/threonine-protein phosphatase. (534 aa)
ENSCVAP00000013785Voltage-dependent anion channel 2. (108 aa)
LOC107090247Mitogen-activated protein kinase kinase 6. (358 aa)
foxm1Forkhead box M1. (649 aa)
LOC107099926Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ppp1ccSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
LOC107102261Calpain 1, (mu/I) large subunit a; Belongs to the peptidase C2 family. (704 aa)
LOC107102257Uncharacterized protein; Belongs to the peptidase C2 family. (683 aa)
LOC107083028Insulin-like growth factor binding protein 3. (283 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC107099902Uncharacterized protein. (471 aa)
mapk1Mitogen-activated protein kinase. (351 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (299 aa)
LOC107095350Forkhead box O1 a. (666 aa)
LOC107091913Zgc:114130. (426 aa)
LOC107083482Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
LOC107088576Mitogen-activated protein kinase. (364 aa)
LOC107102230Fork-head domain-containing protein. (613 aa)
LOC107082405Serine/threonine-protein phosphatase. (516 aa)
LOC107102211Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
ccne2Cyclin E2; Belongs to the cyclin family. (345 aa)
ets1V-ets avian erythroblastosis virus E26 oncogene homolog 1. (485 aa)
zfp36l2Uncharacterized protein. (413 aa)
LOC107102162BHLH domain-containing protein. (368 aa)
calml4Calmodulin-like 4a. (186 aa)
LOC107086239Uncharacterized protein; Belongs to the peptidase C2 family. (693 aa)
lin9Lin-9 DREAM MuvB core complex component. (498 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (301 aa)
LOC107099244Fork-head domain-containing protein. (633 aa)
cdkn2bCyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (124 aa)
LOC107089590Ig-like domain-containing protein; Belongs to the MHC class I family. (321 aa)
LOC107089589Ig-like domain-containing protein; Belongs to the MHC class I family. (328 aa)
IGFBP3Insulin like growth factor binding protein 3. (282 aa)
LOC107099230Nuclear factor of activated T cells 3b. (860 aa)
LOC107098654Homeodomain interacting protein kinase 1a. (1087 aa)
LOC107094672Ribosomal_L7Ae domain-containing protein. (159 aa)
gata4GATA binding protein 4. (395 aa)
VDAC2Voltage dependent anion channel 2. (283 aa)
LOC107083120Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
LOC107096927Uncharacterized protein. (193 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
ccnd3Cyclin D3; Belongs to the cyclin family. (266 aa)
LOC107082804Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
rhebl1Ras homolog, mTORC1 binding like 1. (184 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2406 aa)
ENSCVAP00000020262MIR domain-containing protein. (209 aa)
nbnNibrin. (835 aa)
ENSCVAP00000020525MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (235 aa)
LOC107103873Zgc:55262; Belongs to the peptidase C2 family. (706 aa)
rhebUncharacterized protein. (183 aa)
nfatc3Nuclear factor of activated T cells 3a. (1102 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (162 aa)
sqstm1Sequestosome 1. (435 aa)
ppidPeptidylprolyl isomerase D. (374 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (351 aa)
lin37Lin-37 DREAM MuvB core complex component. (241 aa)
LOC107100856Serine/threonine-protein phosphatase. (518 aa)
LOC107086084Zgc:56235. (282 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2625 aa)
ENSCVAP00000023403Ig-like domain-containing protein; Belongs to the MHC class I family. (347 aa)
mdm2MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (482 aa)
LOC107082647Calpain 2, (m/II) large subunit b; Belongs to the peptidase C2 family. (659 aa)
smad3Mothers against decapentaplegic homolog. (425 aa)
zfp36l1Zinc finger protein 36, C3H type-like 1a. (368 aa)
LOC107097814Uncharacterized protein. (718 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
LOC107091641Sb:cb81. (415 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (285 aa)
LOC107103682Uncharacterized protein. (119 aa)
LOC107084303Cyclin D2, a; Belongs to the cyclin family. (296 aa)
e2f4E2F transcription factor 4. (378 aa)
nfatc2Nuclear factor of activated T cells 2a. (897 aa)
LOC107093847Growth arrest and DNA-damage-inducible, gamma a. (159 aa)
ENSCVAP00000026364Ig-like domain-containing protein; Belongs to the MHC class I family. (353 aa)
rbbp4Retinoblastoma binding protein 4. (424 aa)
LOC107097099RHD domain-containing protein. (869 aa)
LOC107099516Si:ch211-160o17.4. (1141 aa)
LOC107090959Eukaryotic translation initiation factor 4E binding protein 1. (121 aa)
LOC107084790Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (313 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (432 aa)
LOC107089823Serine/threonine-protein phosphatase. (522 aa)
LOC107085244Chemokine (C-X-C motif) ligand 19. (103 aa)
rad50RAD50 homolog, double strand break repair protein. (1274 aa)
ccna1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (389 aa)
cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (325 aa)
LOC107085698Cyclin D2, b; Belongs to the cyclin family. (304 aa)
LOC107082492Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
LOC107094299Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (325 aa)
LOC107096949Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (333 aa)
ENSCVAP00000029189Forkhead box O6 b. (604 aa)
ENSCVAP00000029198V-akt murine thymoma viral oncogene homolog 3b. (181 aa)
ENSCVAP00000029286Ig-like domain-containing protein; Belongs to the MHC class I family. (339 aa)
rad1RAD1 homolog (S. pombe). (279 aa)
LOC107102256Uncharacterized protein; Belongs to the peptidase C2 family. (712 aa)
LOC107102465TSC complex subunit 1b. (1258 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (692 aa)
LOC107094800Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (437 aa)
LOC107082357Inositol 1,4,5-trisphosphate receptor, type 1b. (2672 aa)
LOC107085709Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
hipk3Homeodomain interacting protein kinase 3b. (1333 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (389 aa)
ccnb3Cyclin B3; Belongs to the cyclin family. (430 aa)
LOC107094671Growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1. (154 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (400 aa)
LOC107085054Cyclin B2; Belongs to the cyclin family. (390 aa)
LOC107100954Protein kinase domain-containing protein. (1327 aa)
ppp1cbSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
LOC107085617Cyclin-dependent kinase inhibitor 1A. (168 aa)
relaV-rel avian reticuloendotheliosis viral oncogene homolog A. (622 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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