STRINGSTRING
SUCA SUCA Esi_0173_0060 Esi_0173_0060 Esi_0175_0014 Esi_0175_0014 ACO ACO Esi_0209_0029 Esi_0209_0029 MDH MDH FRD FRD SDH4 SDH4 AAT AAT SDH2 SDH2 Esi_0344_0024 Esi_0344_0024 Esi_0040_0041 Esi_0040_0041 Esi_0464_0010 Esi_0464_0010 Esi_0048_0101 Esi_0048_0101 SDH3 SDH3 FUMH FUMH Esi_0292_0040 Esi_0292_0040 Esi_0038_0096 Esi_0038_0096 MDH4 MDH4 Esi_0062_0031 Esi_0062_0031 SDH1 SDH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SUCASuccinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (322 aa)
Esi_0173_0060Fumarate hydratase. (608 aa)
Esi_0175_0014ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1098 aa)
ACOAconitate hydratase. (788 aa)
Esi_0209_0029Cytosolic malate dehydrogenase. (99 aa)
MDHMalate dehydrogenase. (276 aa)
FRDNADH-dependent fumarate reductase. (535 aa)
SDH4Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (154 aa)
AATAspartate aminotransferase. (401 aa)
SDH2Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
Esi_0344_0024Uncharacterized protein; Belongs to the LDH/MDH superfamily. (399 aa)
Esi_0040_0041Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (463 aa)
Esi_0464_0010Uncharacterized protein. (209 aa)
Esi_0048_0101Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
SDH3SDH3, succinate dehydrogenase subunit 3. (176 aa)
FUMHFumarate hydratase (Fumarase). (482 aa)
Esi_0292_0040Uncharacterized protein. (194 aa)
Esi_0038_00964Fe-4S ferredoxin, iron-sulfur binding. (542 aa)
MDH4Malate dehydrogenase. (349 aa)
Esi_0062_0031Uncharacterized protein. (141 aa)
SDH1SDH1, succinate dehydrogenase subunit 1. (540 aa)
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
Server load: low (24%) [HD]