(22 nodes) Mixed, incl. Coenzyme A biosynthetic process, and Tetrahydrofolylpolyglutamate metabolic process network (Ectocarpus siliculosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Esi_0018_0114	Uncharacterized protein. (731 aa)
	Esi_0212_0025	PRK domain-containing protein. (309 aa)
	Esi_0219_0001	Folate gamma-glutamyl hydrolase. (379 aa)
	Esi_0243_0027	THUMP domain-containing protein. (695 aa)
	Esi_0027_0012	Flavoprotein family enzyme. (91 aa)
	Esi_0003_0306	Pantothenate kinase. (296 aa)
	COX19	COX19 homolog, cytochrome c oxidase assembly protein. (120 aa)
	Esi_0091_0089	Methyltrans_SAM domain-containing protein. (244 aa)
	Esi_0111_0024	ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family. (290 aa)
	Esi_0112_0042	Uncharacterized protein. (338 aa)
	Esi_0181_0049	Methyltrans_SAM domain-containing protein. (257 aa)
	Esi_0022_0060	Rhodanese Homology Domain superfamily. (874 aa)
	Esi_0220_0058	Uncharacterized protein. (347 aa)
	Esi_0030_0091	Rhodanese domain-containing protein. (451 aa)
	Esi_0031_0150	Uncharacterized protein. (539 aa)
	Esi_0044_0118	Uncharacterized protein. (749 aa)
	Esi_0053_0080	Uncharacterized protein. (438 aa)
	Esi_0061_0095	Mur_ligase_M domain-containing protein. (434 aa)
	Esi_0069_0033	Pterin-binding domain-containing protein. (580 aa)
	Esi_0070_0043	Uncharacterized protein. (351 aa)
	Esi_0074_0071	Phosphoribulokinase/uridine kinase family protein. (526 aa)
	Esi_0081_0074	CTP_transf_like domain-containing protein. (457 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COX19	Esi_0003_0306	D7FXT0	D7FW81	COX19 homolog, cytochrome c oxidase assembly protein.	Pantothenate kinase.	0.738
COX19	Esi_0018_0114	D7FXT0	D7FNM0	COX19 homolog, cytochrome c oxidase assembly protein.	Uncharacterized protein.	0.670
COX19	Esi_0022_0060	D7FXT0	D8LIE1	COX19 homolog, cytochrome c oxidase assembly protein.	Rhodanese Homology Domain superfamily.	0.599
COX19	Esi_0030_0091	D7FXT0	D8LKI5	COX19 homolog, cytochrome c oxidase assembly protein.	Rhodanese domain-containing protein.	0.599
COX19	Esi_0031_0150	D7FXT0	D8LL03	COX19 homolog, cytochrome c oxidase assembly protein.	Uncharacterized protein.	0.640
COX19	Esi_0044_0118	D7FXT0	D8LNF9	COX19 homolog, cytochrome c oxidase assembly protein.	Uncharacterized protein.	0.599
COX19	Esi_0053_0080	D7FXT0	D8LPT0	COX19 homolog, cytochrome c oxidase assembly protein.	Uncharacterized protein.	0.788
COX19	Esi_0061_0095	D7FXT0	D8LR03	COX19 homolog, cytochrome c oxidase assembly protein.	Mur_ligase_M domain-containing protein.	0.670
COX19	Esi_0070_0043	D7FXT0	D8LS60	COX19 homolog, cytochrome c oxidase assembly protein.	Uncharacterized protein.	0.753
COX19	Esi_0074_0071	D7FXT0	D8LSL3	COX19 homolog, cytochrome c oxidase assembly protein.	Phosphoribulokinase/uridine kinase family protein.	0.645
COX19	Esi_0081_0074	D7FXT0	D8LTA5	COX19 homolog, cytochrome c oxidase assembly protein.	CTP_transf_like domain-containing protein.	0.789
COX19	Esi_0212_0025	D7FXT0	D7FRA7	COX19 homolog, cytochrome c oxidase assembly protein.	PRK domain-containing protein.	0.645
Esi_0003_0306	COX19	D7FW81	D7FXT0	Pantothenate kinase.	COX19 homolog, cytochrome c oxidase assembly protein.	0.738
Esi_0003_0306	Esi_0027_0012	D7FW81	D7FUB2	Pantothenate kinase.	Flavoprotein family enzyme.	0.738
Esi_0003_0306	Esi_0053_0080	D7FW81	D8LPT0	Pantothenate kinase.	Uncharacterized protein.	0.738
Esi_0003_0306	Esi_0070_0043	D7FW81	D8LS60	Pantothenate kinase.	Uncharacterized protein.	0.913
Esi_0003_0306	Esi_0074_0071	D7FW81	D8LSL3	Pantothenate kinase.	Phosphoribulokinase/uridine kinase family protein.	0.714
Esi_0003_0306	Esi_0112_0042	D7FW81	D8LCZ8	Pantothenate kinase.	Uncharacterized protein.	0.417
Esi_0003_0306	Esi_0212_0025	D7FW81	D7FRA7	Pantothenate kinase.	PRK domain-containing protein.	0.714
Esi_0018_0114	COX19	D7FNM0	D7FXT0	Uncharacterized protein.	COX19 homolog, cytochrome c oxidase assembly protein.	0.670