(10 nodes) HDACs deacetylate histones, and Methyl-CpG binding protein MeCP2/MBD4 network (Ectocarpus siliculosus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Esi_0144_0063	Uncharacterized protein. (419 aa)
	Esi_0147_0031	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (447 aa)
	Esi_0173_0001	FirrV-1-B30. (446 aa)
	Esi_0173_0004	FirrV-1-B30. (491 aa)
	Esi_0194_0017	Myst-related protein. (1620 aa)
	Esi_0002_0237	Chromodomain helicase-DNA-binding protein, putative. (274 aa)
	Esi_0092_0014	WD_REPEATS_REGION domain-containing protein. (874 aa)
	Esi_0121_0045	Uncharacterized protein. (312 aa)
	Esi_0131_0047	WD_REPEATS_REGION domain-containing protein. (294 aa)
	Esi_0181_0051	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (414 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esi_0002_0237	Esi_0092_0014	D7FQ97	D7G8U5	Chromodomain helicase-DNA-binding protein, putative.	WD_REPEATS_REGION domain-containing protein.	0.760
Esi_0002_0237	Esi_0121_0045	D7FQ97	D8LDP6	Chromodomain helicase-DNA-binding protein, putative.	Uncharacterized protein.	0.670
Esi_0002_0237	Esi_0131_0047	D7FQ97	D8LEI3	Chromodomain helicase-DNA-binding protein, putative.	WD_REPEATS_REGION domain-containing protein.	0.760
Esi_0002_0237	Esi_0144_0063	D7FQ97	D7FKJ0	Chromodomain helicase-DNA-binding protein, putative.	Uncharacterized protein.	0.670
Esi_0002_0237	Esi_0147_0031	D7FQ97	D7FKQ3	Chromodomain helicase-DNA-binding protein, putative.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.718
Esi_0002_0237	Esi_0173_0001	D7FQ97	D7FN04	Chromodomain helicase-DNA-binding protein, putative.	FirrV-1-B30.	0.829
Esi_0002_0237	Esi_0173_0004	D7FQ97	D7FN07	Chromodomain helicase-DNA-binding protein, putative.	FirrV-1-B30.	0.829
Esi_0002_0237	Esi_0181_0051	D7FQ97	D8LGV7	Chromodomain helicase-DNA-binding protein, putative.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.718
Esi_0092_0014	Esi_0002_0237	D7G8U5	D7FQ97	WD_REPEATS_REGION domain-containing protein.	Chromodomain helicase-DNA-binding protein, putative.	0.760
Esi_0092_0014	Esi_0121_0045	D7G8U5	D8LDP6	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.879
Esi_0092_0014	Esi_0144_0063	D7G8U5	D7FKJ0	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.879
Esi_0092_0014	Esi_0147_0031	D7G8U5	D7FKQ3	WD_REPEATS_REGION domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.929
Esi_0092_0014	Esi_0173_0001	D7G8U5	D7FN04	WD_REPEATS_REGION domain-containing protein.	FirrV-1-B30.	0.998
Esi_0092_0014	Esi_0173_0004	D7G8U5	D7FN07	WD_REPEATS_REGION domain-containing protein.	FirrV-1-B30.	0.998
Esi_0092_0014	Esi_0181_0051	D7G8U5	D8LGV7	WD_REPEATS_REGION domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.929
Esi_0092_0014	Esi_0194_0017	D7G8U5	D7FPM2	WD_REPEATS_REGION domain-containing protein.	Myst-related protein.	0.760
Esi_0121_0045	Esi_0002_0237	D8LDP6	D7FQ97	Uncharacterized protein.	Chromodomain helicase-DNA-binding protein, putative.	0.670
Esi_0121_0045	Esi_0092_0014	D8LDP6	D7G8U5	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.879
Esi_0121_0045	Esi_0131_0047	D8LDP6	D8LEI3	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.879
Esi_0121_0045	Esi_0147_0031	D8LDP6	D7FKQ3	Uncharacterized protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.819