(20 nodes) Mixed, incl. MTOR signalling, and The FATC domain is named after FRAP, ATM, TRRAP C-terminal (PMID:10782091). The solution structure of the FATC domain suggests it plays a role in redox-dependent structural and cellular stability (PMID:15772072). network (Ectocarpus siliculosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Esi_0101_0064	Serine/threonine protein kinase. (605 aa)
	Esi_0115_0028	FHA domain-containing protein. (335 aa)
	RAP	Raptor. (928 aa)
	Esi_0122_0033	Uncharacterized protein. (466 aa)
	Esi_0153_0048	WD40 repeat containing protein. (304 aa)
	PK-7	Protein kinase 2. (774 aa)
	Esi_0029_0119	annotation not available (351 aa)
	S6K	Non-specific serine/threonine protein kinase. (593 aa)
	TOR2	Target of rapamycin 2; Belongs to the PI3/PI4-kinase family. (1929 aa)
	GTR2	GTR2, Ras superfamily GTPase. (380 aa)
	TOR1	Target of rapamycin 1; Belongs to the PI3/PI4-kinase family. (3331 aa)
	Esi_0491_0016	Uncharacterized protein. (756 aa)
	Esi_0619_0005	Non-specific serine/threonine protein kinase. (591 aa)
	Esi_0625_0005	Uncharacterized protein. (569 aa)
	cAMP-PK-2	cAMP-dependent protein kinase catalytic subunit (PKA)-like. (769 aa)
	Esi_0024_0130	PX domain-containing protein. (255 aa)
	Esi_0301_0022	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (410 aa)
	Esi_0053_0026	Uncharacterized protein. (1369 aa)
	Esi_0059_0014	Choline/ethanolamine kinase. (416 aa)
	GTR1	GTR1, Ras superfamily GTPase. (319 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esi_0024_0130	Esi_0029_0119	D8LJ85	D7FVD9	PX domain-containing protein.	annotation not available	0.759
Esi_0024_0130	Esi_0053_0026	D8LJ85	D8LPP5	PX domain-containing protein.	Uncharacterized protein.	0.792
Esi_0024_0130	Esi_0059_0014	D8LJ85	D8LQ37	PX domain-containing protein.	Choline/ethanolamine kinase.	0.646
Esi_0024_0130	Esi_0101_0064	D8LJ85	D7FGS5	PX domain-containing protein.	Serine/threonine protein kinase.	0.514
Esi_0024_0130	Esi_0115_0028	D8LJ85	D7FHX7	PX domain-containing protein.	FHA domain-containing protein.	0.910
Esi_0024_0130	Esi_0122_0033	D8LJ85	D7FIL7	PX domain-containing protein.	Uncharacterized protein.	0.737
Esi_0024_0130	Esi_0153_0048	D8LJ85	D7FL41	PX domain-containing protein.	WD40 repeat containing protein.	0.661
Esi_0024_0130	Esi_0301_0022	D8LJ85	D8LKP5	PX domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.803
Esi_0024_0130	Esi_0491_0016	D8LJ85	D7G335	PX domain-containing protein.	Uncharacterized protein.	0.928
Esi_0024_0130	Esi_0619_0005	D8LJ85	D7G543	PX domain-containing protein.	Non-specific serine/threonine protein kinase.	0.687
Esi_0024_0130	Esi_0625_0005	D8LJ85	D7G554	PX domain-containing protein.	Uncharacterized protein.	0.803
Esi_0024_0130	GTR1	D8LJ85	D8LQF2	PX domain-containing protein.	GTR1, Ras superfamily GTPase.	0.572
Esi_0024_0130	GTR2	D8LJ85	D7FZ21	PX domain-containing protein.	GTR2, Ras superfamily GTPase.	0.531
Esi_0024_0130	PK-7	D8LJ85	D7FTC6	PX domain-containing protein.	Protein kinase 2.	0.687
Esi_0024_0130	RAP	D8LJ85	D7FIL6	PX domain-containing protein.	Raptor.	0.737
Esi_0024_0130	S6K	D8LJ85	D7FW58	PX domain-containing protein.	Non-specific serine/threonine protein kinase.	0.514
Esi_0024_0130	TOR1	D8LJ85	D7G264	PX domain-containing protein.	Target of rapamycin 1; Belongs to the PI3/PI4-kinase family.	0.803
Esi_0024_0130	TOR2	D8LJ85	D7FYJ6	PX domain-containing protein.	Target of rapamycin 2; Belongs to the PI3/PI4-kinase family.	0.803
Esi_0024_0130	cAMP-PK-2	D8LJ85	D8LH93	PX domain-containing protein.	cAMP-dependent protein kinase catalytic subunit (PKA)-like.	0.514
Esi_0029_0119	Esi_0024_0130	D7FVD9	D8LJ85	annotation not available	PX domain-containing protein.	0.759