(5 nodes) Extra-nuclear estrogen signaling, and The FATC domain is named after FRAP, ATM, TRRAP C-terminal (PMID:10782091). The solution structure of the FATC domain suggests it plays a role in redox-dependent structural and cellular stability (PMID:15772072). network (Ectocarpus siliculosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PK-7	Protein kinase 2. (774 aa)
	Esi_0029_0119	annotation not available (351 aa)
	Esi_0491_0016	Uncharacterized protein. (756 aa)
	Esi_0024_0130	PX domain-containing protein. (255 aa)
	Esi_0301_0022	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (410 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esi_0024_0130	Esi_0029_0119	D8LJ85	D7FVD9	PX domain-containing protein.	annotation not available	0.759
Esi_0024_0130	Esi_0301_0022	D8LJ85	D8LKP5	PX domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.803
Esi_0024_0130	Esi_0491_0016	D8LJ85	D7G335	PX domain-containing protein.	Uncharacterized protein.	0.928
Esi_0024_0130	PK-7	D8LJ85	D7FTC6	PX domain-containing protein.	Protein kinase 2.	0.687
Esi_0029_0119	Esi_0024_0130	D7FVD9	D8LJ85	annotation not available	PX domain-containing protein.	0.759
Esi_0029_0119	Esi_0301_0022	D7FVD9	D8LKP5	annotation not available	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.803
Esi_0029_0119	Esi_0491_0016	D7FVD9	D7G335	annotation not available	Uncharacterized protein.	0.928
Esi_0029_0119	PK-7	D7FVD9	D7FTC6	annotation not available	Protein kinase 2.	0.687
Esi_0301_0022	Esi_0024_0130	D8LKP5	D8LJ85	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	PX domain-containing protein.	0.803
Esi_0301_0022	Esi_0029_0119	D8LKP5	D7FVD9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	annotation not available	0.803
Esi_0301_0022	PK-7	D8LKP5	D7FTC6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase 2.	0.712
Esi_0491_0016	Esi_0024_0130	D7G335	D8LJ85	Uncharacterized protein.	PX domain-containing protein.	0.928
Esi_0491_0016	Esi_0029_0119	D7G335	D7FVD9	Uncharacterized protein.	annotation not available	0.928
Esi_0491_0016	PK-7	D7G335	D7FTC6	Uncharacterized protein.	Protein kinase 2.	0.971
PK-7	Esi_0024_0130	D7FTC6	D8LJ85	Protein kinase 2.	PX domain-containing protein.	0.687
PK-7	Esi_0029_0119	D7FTC6	D7FVD9	Protein kinase 2.	annotation not available	0.687
PK-7	Esi_0301_0022	D7FTC6	D8LKP5	Protein kinase 2.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.712
PK-7	Esi_0491_0016	D7FTC6	D7G335	Protein kinase 2.	Uncharacterized protein.	0.971