(54 nodes) Antioxidant activity network (Ectocarpus siliculosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Esi_1402_0001	Nucleoredoxin, putative. (215 aa)
	Esi_0130_0046	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (225 aa)
	Esi_0119_0001	Glutathione reductase. (229 aa)
	ycf42	Putative peroxiredoxin ycf42. (186 aa)
	GSR-2	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (482 aa)
	PRX5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (205 aa)
	SELU	Peroxiredoxin-like protein. (213 aa)
	Gpx4	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (169 aa)
	Esi_0007_0066	AhpC/TSA family protein. (192 aa)
	Esi_0066_0123	Hypothetical leucine rich repeat protein. (405 aa)
	GPX	Glutathione peroxidase. (290 aa)
	Esi_0049_0049	Uncharacterized protein. (268 aa)
	GPX-2	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (239 aa)
	Esi_0051_0039	Electron donor (NADH / NADPH)-dependent reductase. (520 aa)
	Esi_0073_0068	Thioredoxin. (166 aa)
	PRX2	2-cys peroxiredoxin. (386 aa)
	SELT	Selenoprotein T. (307 aa)
	Esi_0083_0090	Peroxidase. (1489 aa)
	Esi_0083_0098	Peroxidase. (1490 aa)
	Esi_0262_0037	Uncharacterized protein. (322 aa)
	GSR	Glutathione reductase. (323 aa)
	Esi_0023_0152	Thioredoxin. (528 aa)
	Esi_0032_0017	Peroxinectin. (639 aa)
	Fe-2	annotation not available (169 aa)
	CAT-4	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (538 aa)
	DOX	Alpha-dioxygenase. (353 aa)
	Fe-3	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (196 aa)
	GPX-5	Glutathione peroxidase. (225 aa)
	Esi_0254_0022	Thioredoxin domain-containing protein. (147 aa)
	TrxR	Thioredoxin reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (773 aa)
	MSD	Manganese superoxide dismutase. (300 aa)
	Esi_0000_0287	Peroxinectin. (763 aa)
	Esi_0010_0091	Thioredoxin domain-containing protein. (428 aa)
	Esi_0103_0059	Uncharacterized protein. (3264 aa)
	Esi_0014_0002	Soluble pyridine nucleotide transhydrogenase. (403 aa)
	Esi_0014_0065	Thioredoxin domain-containing protein. (250 aa)
	Esi_0244_0019	Uncharacterized protein. (373 aa)
	Esi_0239_0009	Hypothetical leucine rich repeat protein. (163 aa)
	Fe	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (229 aa)
	putative-2	Disproportionate superoxide radical into hydrogen peroxide. (156 aa)
	Esi_0021_0053	Thioredoxin domain-containing protein. (190 aa)
	Esi_0209_0042	Peroxidase. (1264 aa)
	putativeMnSOD	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (230 aa)
	Esi_0173_0040	Thioredoxin domain-containing protein. (162 aa)
	putative	Copper/zinc superoxide dismutase. (116 aa)
	GPX-4	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (176 aa)
	GPX-3	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (176 aa)
	Esi_0015_0018	Peroxiredoxin family protein. (218 aa)
	Esi_0148_0052	Peroxidase. (1627 aa)
	Esi_0044_0092	PITH domain-containing protein. (184 aa)
	GPX-6	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (194 aa)
	FeSOD	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (230 aa)
	Esi_0030_0003	Thioredoxin reductase. (400 aa)
	Esi_0281_0018	Peroxiredoxin or Alkyl hydroperoxide reductase/ Thiol specific antioxidant. (233 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAT-4	DOX	D7G1K9	D8LJL3	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Alpha-dioxygenase.	0.578
CAT-4	Esi_0000_0287	D7G1K9	D8LB73	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxinectin.	0.578
CAT-4	Esi_0014_0002	D7G1K9	D8LER9	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Soluble pyridine nucleotide transhydrogenase.	0.522
CAT-4	Esi_0014_0065	D7G1K9	D8LEU8	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin domain-containing protein.	0.787
CAT-4	Esi_0030_0003	D7G1K9	D8LKE0	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin reductase.	0.634
CAT-4	Esi_0032_0017	D7G1K9	D7FX03	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxinectin.	0.578
CAT-4	Esi_0051_0039	D7G1K9	D7G3G5	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Electron donor (NADH / NADPH)-dependent reductase.	0.402
CAT-4	Esi_0066_0123	D7G1K9	D8LRJ1	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Hypothetical leucine rich repeat protein.	0.603
CAT-4	Esi_0083_0090	D7G1K9	D7G7J1	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxidase.	0.578
CAT-4	Esi_0083_0098	D7G1K9	D7G7J2	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxidase.	0.578
CAT-4	Esi_0119_0001	D7G1K9	D7FI97	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione reductase.	0.522
CAT-4	Esi_0130_0046	D7G1K9	D7FJA5	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.455
CAT-4	Esi_0148_0052	D7G1K9	D8LFE6	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxidase.	0.578
CAT-4	Esi_0209_0042	D7G1K9	D7FQW8	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxidase.	0.578
CAT-4	Esi_0239_0009	D7G1K9	D7FSS3	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Hypothetical leucine rich repeat protein.	0.603
CAT-4	Fe	D7G1K9	D7FRS6	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.688
CAT-4	Fe-2	D7G1K9	D7FYD2	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	annotation not available	0.688
CAT-4	Fe-3	D7G1K9	D8LI17	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.688
CAT-4	FeSOD	D7G1K9	D8LN00	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.688
CAT-4	GPX	D7G1K9	D7G2W3	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase.	0.574