(16 nodes) Macroautophagy network (Ectocarpus siliculosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Atg9	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (985 aa)
	Atg12	Ubiquitin-like protein ATG12. (231 aa)
	Esi_0515_0001	Uncharacterized protein. (244 aa)
	Esi_0192_0021	Uncharacterized protein. (2777 aa)
	Esi_0283_0002	Uncharacterized protein. (135 aa)
	Esi_0044_0148	Putative phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family. (1781 aa)
	Esi_0007_0111	Conserved protein. (1460 aa)
	Esi_0110_0037	Beclin-1, putative. (650 aa)
	Esi_0115_0039	Putative phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family. (1039 aa)
	Atg11	Autophagy-related protein 11. (1216 aa)
	Atg6	Beclin. (416 aa)
	Esi_0149_0056	ATG13 domain-containing protein. (691 aa)
	Esi_0205_0059	Uncharacterized protein. (1463 aa)
	Esi_0205_0057	Uncharacterized protein. (412 aa)
	Esi_0211_0012	Uncharacterized protein. (264 aa)
	Esi_0226_0021	Uncharacterized protein. (900 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atg11	Atg12	D7FIX1	D7G0N6	Autophagy-related protein 11.	Ubiquitin-like protein ATG12.	0.707
Atg11	Atg6	D7FIX1	D7FJA3	Autophagy-related protein 11.	Beclin.	0.966
Atg11	Atg9	D7FIX1	D7FZF2	Autophagy-related protein 11.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.670
Atg11	Esi_0007_0111	D7FIX1	D8LRQ5	Autophagy-related protein 11.	Conserved protein.	0.810
Atg11	Esi_0044_0148	D7FIX1	D8LNH7	Autophagy-related protein 11.	Putative phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family.	0.769
Atg11	Esi_0110_0037	D7FIX1	D7FHQ7	Autophagy-related protein 11.	Beclin-1, putative.	0.966
Atg11	Esi_0115_0039	D7FIX1	D7FHY6	Autophagy-related protein 11.	Putative phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family.	0.769
Atg11	Esi_0149_0056	D7FIX1	D7FKW0	Autophagy-related protein 11.	ATG13 domain-containing protein.	0.820
Atg11	Esi_0283_0002	D7FIX1	D8LK81	Autophagy-related protein 11.	Uncharacterized protein.	0.998
Atg12	Atg11	D7G0N6	D7FIX1	Ubiquitin-like protein ATG12.	Autophagy-related protein 11.	0.707
Atg12	Atg6	D7G0N6	D7FJA3	Ubiquitin-like protein ATG12.	Beclin.	0.895
Atg12	Atg9	D7G0N6	D7FZF2	Ubiquitin-like protein ATG12.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.811
Atg12	Esi_0007_0111	D7G0N6	D8LRQ5	Ubiquitin-like protein ATG12.	Conserved protein.	0.823
Atg12	Esi_0044_0148	D7G0N6	D8LNH7	Ubiquitin-like protein ATG12.	Putative phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family.	0.778
Atg12	Esi_0110_0037	D7G0N6	D7FHQ7	Ubiquitin-like protein ATG12.	Beclin-1, putative.	0.850
Atg12	Esi_0115_0039	D7G0N6	D7FHY6	Ubiquitin-like protein ATG12.	Putative phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family.	0.778
Atg12	Esi_0283_0002	D7G0N6	D8LK81	Ubiquitin-like protein ATG12.	Uncharacterized protein.	0.500
Atg6	Atg11	D7FJA3	D7FIX1	Beclin.	Autophagy-related protein 11.	0.966
Atg6	Atg12	D7FJA3	D7G0N6	Beclin.	Ubiquitin-like protein ATG12.	0.895
Atg6	Atg9	D7FJA3	D7FZF2	Beclin.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.891