(10 nodes) Hydroxymethyl-, formyl- and related transferase activity network (Ectocarpus siliculosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FMT	Methionyl-tRNA formyltransferase. (451 aa)
	Esi_0019_0094	Folate-binding protein YgfZ. (544 aa)
	Esi_0019_0004	ACT domain-containing protein. (339 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (471 aa)
	Esi_0112_0042	Uncharacterized protein. (338 aa)
	Esi_0046_0033	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (419 aa)
	SHMT2-3	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (491 aa)
	Esi_0081_0020	ATP-grasp domain-containing protein. (1217 aa)
	SHMT2-2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (538 aa)
	Esi_0031_0020	Probable bifunctional purine synthesis protein. (610 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esi_0019_0004	Esi_0019_0094	D8LH40	D8LH90	ACT domain-containing protein.	Folate-binding protein YgfZ.	0.701
Esi_0019_0004	Esi_0031_0020	D8LH40	D8LKS8	ACT domain-containing protein.	Probable bifunctional purine synthesis protein.	0.957
Esi_0019_0004	Esi_0046_0033	D8LH40	D7G1U3	ACT domain-containing protein.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.701
Esi_0019_0004	Esi_0081_0020	D8LH40	D8LT70	ACT domain-containing protein.	ATP-grasp domain-containing protein.	0.962
Esi_0019_0004	FMT	D8LH40	D8LKZ7	ACT domain-containing protein.	Methionyl-tRNA formyltransferase.	0.774
Esi_0019_0004	SHMT2	D8LH40	D8LFD6	ACT domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.842
Esi_0019_0004	SHMT2-2	D8LH40	D8LL78	ACT domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.842
Esi_0019_0004	SHMT2-3	D8LH40	D8LUA3	ACT domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.842
Esi_0019_0094	Esi_0019_0004	D8LH90	D8LH40	Folate-binding protein YgfZ.	ACT domain-containing protein.	0.701
Esi_0019_0094	Esi_0031_0020	D8LH90	D8LKS8	Folate-binding protein YgfZ.	Probable bifunctional purine synthesis protein.	0.815
Esi_0019_0094	Esi_0081_0020	D8LH90	D8LT70	Folate-binding protein YgfZ.	ATP-grasp domain-containing protein.	0.944
Esi_0019_0094	FMT	D8LH90	D8LKZ7	Folate-binding protein YgfZ.	Methionyl-tRNA formyltransferase.	0.757
Esi_0019_0094	SHMT2	D8LH90	D8LFD6	Folate-binding protein YgfZ.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.843
Esi_0019_0094	SHMT2-2	D8LH90	D8LL78	Folate-binding protein YgfZ.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.843
Esi_0019_0094	SHMT2-3	D8LH90	D8LUA3	Folate-binding protein YgfZ.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.843
Esi_0031_0020	Esi_0019_0004	D8LKS8	D8LH40	Probable bifunctional purine synthesis protein.	ACT domain-containing protein.	0.957
Esi_0031_0020	Esi_0019_0094	D8LKS8	D8LH90	Probable bifunctional purine synthesis protein.	Folate-binding protein YgfZ.	0.815
Esi_0031_0020	Esi_0046_0033	D8LKS8	D7G1U3	Probable bifunctional purine synthesis protein.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.815
Esi_0031_0020	Esi_0081_0020	D8LKS8	D8LT70	Probable bifunctional purine synthesis protein.	ATP-grasp domain-containing protein.	0.998
Esi_0031_0020	FMT	D8LKS8	D8LKZ7	Probable bifunctional purine synthesis protein.	Methionyl-tRNA formyltransferase.	0.769