(27 nodes) Branched-chain amino acid catabolism network (Ectocarpus siliculosus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	Esi_0006_0185	Mercuric reductase. (573 aa)
	Esi_0053_0040	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa)
	GCSL-2	Dihydrolipoamide dehydrogenase. (544 aa)
	Esi_0030_0175	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (293 aa)
	BCAT4	Branched chain amino acid aminotransferase. (614 aa)
	GCSL	Dihydrolipoyl dehydrogenase. (502 aa)
	Esi_0098_0083	Mercuric reductase A. (399 aa)
	Esi_0109_0084	Naphthoate synthase, partial. (116 aa)
	Esi_0123_0030	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (380 aa)
	Esi_0016_0199	Enoyl-CoA hydratase. (260 aa)
	Esi_0018_0039	Enoyl-CoA hydratase domain-containing protein; Belongs to the enoyl-CoA hydratase/isomerase family. (229 aa)
	Esi_0002_0203	Uncharacterized protein. (370 aa)
	Esi_0144_0069	Uncharacterized protein. (612 aa)
	Esi_0108_0050	Uncharacterized protein. (514 aa)
	Esi_0358_0029	Branched chain alpha-keto acid dehydrogenase E1 beta subunit. (451 aa)
	Esi_0109_0081	Naphthoate synthase. (114 aa)
	Esi_0109_0083	Naphthoate synthase; Belongs to the enoyl-CoA hydratase/isomerase family. (146 aa)
	Esi_0032_0021	Methylmalonate Semialdehyde Dehydrogenase. (526 aa)
	BCAT3-2	C-terminal branched chain amino acid aminotransferase BACT3. (116 aa)
	BCAT3	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (430 aa)
	BCAT2	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (405 aa)
	BCAT1	Branched chain amino acid aminotransferase. (352 aa)
	Esi_0358_0027	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (623 aa)
	Esi_0070_0044	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (328 aa)
	Esi_0007_0146	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (407 aa)
	MSDH	Methylmalonate Semialdehyde Dehydrogenase. (503 aa)
	Esi_0006_0214	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCAT1	Esi_0006_0214	D8LT73	D8LQN6	Branched chain amino acid aminotransferase.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.825
BCAT1	Esi_0358_0027	D8LT73	D7FZ94	Branched chain amino acid aminotransferase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.624
BCAT1	Esi_0358_0029	D8LT73	D7FZ95	Branched chain amino acid aminotransferase.	Branched chain alpha-keto acid dehydrogenase E1 beta subunit.	0.852
BCAT2	Esi_0006_0214	D8LT74	D8LQN6	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.825
BCAT2	Esi_0358_0027	D8LT74	D7FZ94	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.624
BCAT2	Esi_0358_0029	D8LT74	D7FZ95	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Branched chain alpha-keto acid dehydrogenase E1 beta subunit.	0.852
BCAT3	Esi_0006_0214	D8LT77	D8LQN6	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.666
BCAT3	Esi_0358_0027	D8LT77	D7FZ94	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.624
BCAT3	Esi_0358_0029	D8LT77	D7FZ95	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Branched chain alpha-keto acid dehydrogenase E1 beta subunit.	0.716
BCAT3-2	Esi_0006_0214	D8LT78	D8LQN6	C-terminal branched chain amino acid aminotransferase BACT3.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.666
BCAT3-2	Esi_0358_0027	D8LT78	D7FZ94	C-terminal branched chain amino acid aminotransferase BACT3.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.624
BCAT3-2	Esi_0358_0029	D8LT78	D7FZ95	C-terminal branched chain amino acid aminotransferase BACT3.	Branched chain alpha-keto acid dehydrogenase E1 beta subunit.	0.716
BCAT4	Esi_0006_0214	D8LIS9	D8LQN6	Branched chain amino acid aminotransferase.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.825
BCAT4	Esi_0358_0027	D8LIS9	D7FZ94	Branched chain amino acid aminotransferase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.624
BCAT4	Esi_0358_0029	D8LIS9	D7FZ95	Branched chain amino acid aminotransferase.	Branched chain alpha-keto acid dehydrogenase E1 beta subunit.	0.852
Esi_0002_0203	Esi_0006_0214	D7FQ75	D8LQN6	Uncharacterized protein.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.666
Esi_0002_0203	Esi_0358_0027	D7FQ75	D7FZ94	Uncharacterized protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.624
Esi_0002_0203	Esi_0358_0029	D7FQ75	D7FZ95	Uncharacterized protein.	Branched chain alpha-keto acid dehydrogenase E1 beta subunit.	0.716
Esi_0006_0185	Esi_0006_0214	D8LQL6	D8LQN6	Mercuric reductase.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.831
Esi_0006_0185	Esi_0358_0027	D8LQL6	D7FZ94	Mercuric reductase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.927