64 items (Ectocarpus siliculosus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Esi_0165_0035	Uncharacterized protein. (620 aa)
	Esi_0198_0013	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1136 aa)
	PK-49	Similar to doublecortin and CaM kinase-like 3. (753 aa)
	Esi_0271_0004	Mitogen-activated protein kinase. (515 aa)
	Esi_0271_0006	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (437 aa)
	Esi_0409_0013	Component of SCAR regulatory complex. (955 aa)
	MAPK-8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (656 aa)
	MAPK-9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (557 aa)
	Esi_0053_0026	Uncharacterized protein. (1369 aa)
	Esi_0006_0020	CTLH domain-containing protein. (474 aa)
	Esi_0006_0021	B30.2/SPRY domain-containing protein. (306 aa)
	Esi_0062_0090	Uncharacterized protein. (223 aa)
	Esi_0007_0126	Uncharacterized protein. (222 aa)
	Esi_0070_0049	Ubiquitin. (129 aa)
	Esi_0009_0071	Ubiquitin-like domain-containing protein. (78 aa)
	Esi_0009_0210	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (582 aa)
	Esi_0090_0078	Uncharacterized protein. (617 aa)
	Esi_0277_0028	Protein kinase domain-containing protein. (223 aa)
	atpH	ATP synthase subunit c, chloroplastic; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (82 aa)
	Esi_1053_0006	V-ATPase_H_C domain-containing protein. (92 aa)
	Esi_0123_0067	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (485 aa)
	Esi_0136_0046	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	Esi_0143_0011	B30.2/SPRY domain-containing protein. (714 aa)
	Esi_0143_0068	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (117 aa)
	Esi_0150_0046	Uncharacterized protein. (377 aa)
	Esi_0153_0048	WD40 repeat containing protein. (304 aa)
	Esi_0016_0133	Uncharacterized protein. (261 aa)
	PP2A	Serine/threonine-protein phosphatase. (312 aa)
	Esi_0017_0207	PDZ domain-containing protein. (2331 aa)
	Esi_0193_0063	V-type h-atpase subunit; Belongs to the V-ATPase proteolipid subunit family. (187 aa)
	Esi_0002_0045	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (975 aa)
	Esi_0208_0047	Putative bis(5'-nucleosyl)-tetraphosphatase, symmetrical. (101 aa)
	Esi_0232_0004	Ncstrn_small domain-containing protein. (884 aa)
	Esi_0025_0007	Uncharacterized protein. (634 aa)
	PK-7	Protein kinase 2. (774 aa)
	Esi_0025_0156	EGF-like domain-containing protein. (191 aa)
	Esi_0265_0005	Metallophos domain-containing protein. (994 aa)
	Esi_0029_0111	Protein phosphatase 2A regulatory subunit. (586 aa)
	Esi_0003_0116	Zinc finger, FYVE domain containing 19, isoform CRA_g. (392 aa)
	Esi_0033_0132	Uncharacterized protein. (361 aa)
	Esi_0403_0008	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (479 aa)
	Esi_0048_0106	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (438 aa)
	Esi_0491_0016	Uncharacterized protein. (756 aa)
	Esi_0499_0007	Uncharacterized protein. (418 aa)
	Esi_0619_0005	Non-specific serine/threonine protein kinase. (591 aa)
	Esi_0065_0095	BZIP domain-containing protein. (389 aa)
	Esi_0068_0027	Uncharacterized protein. (351 aa)
	MAPK-4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
	MAPK-5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
	Esi_0008_0099	UBA domain-containing protein. (1965 aa)
	MAPK-6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (457 aa)
	Esi_0008_0224	SPRY domain-containing protein. (464 aa)
	Esi_0091_0095	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (164 aa)
	Esi_0000_0121	Uncharacterized protein. (396 aa)
	MAPK-7	Mitogen-activated protein kinase. (1790 aa)
	Esi_0000_0630	Arf-GAP domain-containing protein. (390 aa)
	Esi_0111_0009	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (497 aa)
	Esi_0111_0020	Serine/threonine-protein phosphatase. (320 aa)
	Esi_0012_0022	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (168 aa)
	Esi_0013_0071	Similar to ubiquitin and ribosomal protein S27a. (100 aa)
	Esi_0131_0026	SH3 domain-containing protein. (520 aa)
	Esi_0141_0059	Uncharacterized protein. (532 aa)
	Esi_0145_0034	SH3 domain-containing protein. (459 aa)
	Esi_0015_0023	WD_REPEATS_REGION domain-containing protein. (466 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esi_0000_0121	Esi_0002_0045	D8LAZ9	D7FPY6	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.999
Esi_0000_0121	Esi_0012_0022	D8LAZ9	D8LDE7	Uncharacterized protein.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.996
Esi_0000_0121	Esi_0016_0133	D8LAZ9	D7FLL6	Uncharacterized protein.	Uncharacterized protein.	0.999
Esi_0000_0121	Esi_0033_0132	D8LAZ9	D7FXN6	Uncharacterized protein.	Uncharacterized protein.	0.993
Esi_0000_0121	Esi_0048_0106	D8LAZ9	D7G2Q6	Uncharacterized protein.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.997
Esi_0000_0121	Esi_0062_0090	D8LAZ9	D8LR53	Uncharacterized protein.	Uncharacterized protein.	0.999
Esi_0000_0121	Esi_0091_0095	D8LAZ9	D7G8S5	Uncharacterized protein.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.996
Esi_0000_0121	Esi_0111_0009	D8LAZ9	D8LCT6	Uncharacterized protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.999
Esi_0000_0121	Esi_0136_0046	D8LAZ9	D7FJS2	Uncharacterized protein.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.997
Esi_0000_0121	Esi_0143_0068	D8LAZ9	D7FKE2	Uncharacterized protein.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.998
Esi_0000_0121	Esi_0165_0035	D8LAZ9	D8LGA9	Uncharacterized protein.	Uncharacterized protein.	0.999
Esi_0000_0121	Esi_0193_0063	D8LAZ9	D7FPL3	Uncharacterized protein.	V-type h-atpase subunit; Belongs to the V-ATPase proteolipid subunit family.	0.999
Esi_0000_0121	Esi_1053_0006	D8LAZ9	D7FH73	Uncharacterized protein.	V-ATPase_H_C domain-containing protein.	0.993
Esi_0000_0121	atpH	D8LAZ9	D1J793	Uncharacterized protein.	ATP synthase subunit c, chloroplastic; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	0.996
Esi_0002_0045	Esi_0000_0121	D7FPY6	D8LAZ9	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.999
Esi_0002_0045	Esi_0012_0022	D7FPY6	D8LDE7	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.995
Esi_0002_0045	Esi_0016_0133	D7FPY6	D7FLL6	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.997
Esi_0002_0045	Esi_0033_0132	D7FPY6	D7FXN6	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.987
Esi_0002_0045	Esi_0048_0106	D7FPY6	D7G2Q6	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.996
Esi_0002_0045	Esi_0062_0090	D7FPY6	D8LR53	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.999