(69 nodes) Lysine degradation network (Ectocarpus siliculosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Esi_0020_0054	Uncharacterized protein. (3157 aa)
	Esi_0022_0119	Uncharacterized protein. (403 aa)
	CDK	Possible Cdc2-related protein kinase. (1898 aa)
	GCSL-2	Dihydrolipoamide dehydrogenase. (544 aa)
	Esi_0038_0076	Uncharacterized protein. (237 aa)
	Esi_0401_0016	PHB domain-containing protein. (273 aa)
	Esi_0043_0074	Whsc1 protein. (1551 aa)
	Esi_0005_0166	Set domain protein. (445 aa)
	Esi_0006_0185	Mercuric reductase. (573 aa)
	Esi_0062_0012	Fe2OG dioxygenase domain-containing protein. (713 aa)
	Esi_0064_0103	SET domain-containing protein. (457 aa)
	Esi_0069_0089	Uncharacterized protein. (3474 aa)
	Esi_0007_0090	DOT1 domain-containing protein. (285 aa)
	Esi_0070_0045	Histone methyltransferase. (2067 aa)
	Esi_0076_0098	Uncharacterized protein. (292 aa)
	Esi_0115_0076	GF22528. (1516 aa)
	Esi_0125_0070	SET domain-containing protein. (401 aa)
	Esi_0144_0031	Protein kinase domain-containing protein. (1328 aa)
	Esi_0144_0069	Uncharacterized protein. (612 aa)
	Esi_0016_0010	TauD domain-containing protein. (273 aa)
	Esi_0016_0065	Uncharacterized protein. (902 aa)
	Esi_0016_0129	Uncharacterized protein. (810 aa)
	Esi_0162_0064	Similar to SET domain, bifurcated 1. (1012 aa)
	Esi_0169_0045	SET domain-containing protein. (653 aa)
	Esi_0189_0013	Set and mynd domain containing. (589 aa)
	Esi_0189_0015	SET and MYND domain containing 1b. (488 aa)
	Esi_0203_0021	ANK_REP_REGION domain-containing protein. (215 aa)
	Esi_0216_0035	Excinuclease ABC subunit B. (1015 aa)
	Esi_0226_0046	Uncharacterized protein. (585 aa)
	Esi_0231_0032	DUF4200 domain-containing protein. (311 aa)
	Esi_0268_0001	Histone-lysine N-methyltransferase. (280 aa)
	Esi_0278_0025	SET and MYND domain containing 3. (636 aa)
	Esi_0286_0007	Set and mynd domain containing protein, putative. (586 aa)
	Esi_0286_0020	Rab-GAP TBC domain-containing protein. (923 aa)
	Esi_0305_0003	Dihydrolipoamide succinyltransferase. (300 aa)
	Esi_0033_0112	Uncharacterized protein. (510 aa)
	Esi_0034_0078	DOT1 domain-containing protein. (463 aa)
	Esi_0350_0001	TauD domain-containing protein. (244 aa)
	Esi_0435_0001	Uncharacterized protein. (552 aa)
	Esi_0453_0004	SET domain-containing protein. (702 aa)
	Esi_0455_0010	SET domain-containing protein. (209 aa)
	Esi_0047_0134	EsV-1-1. (188 aa)
	Esi_0475_0005	Predicted: Tubulin-tyrosine ligase-related protein. (720 aa)
	Esi_0048_0019	Similar to SPFH domain family, member 1. (373 aa)
	Esi_0048_0048	Uncharacterized protein. (373 aa)
	Esi_0504_0003	Uncharacterized protein. (465 aa)
	Esi_0051_0056	Uncharacterized protein. (306 aa)
	Esi_0547_0011	EsV-1-1. (187 aa)
	Esi_0073_0036	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (409 aa)
	Esi_0084_0080	Uncharacterized protein. (566 aa)
	ACAT1	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	Esi_0094_0082	Uncharacterized protein. (330 aa)
	Esi_0098_0083	Mercuric reductase A. (399 aa)
	Esi_0000_0259	Uncharacterized protein. (2317 aa)
	Esi_0000_0373	Uncharacterized protein. (207 aa)
	GCSL	Dihydrolipoyl dehydrogenase. (502 aa)
	Esi_0010_0170	TPR Domain containing protein. (596 aa)
	Esi_0100_0024	SET domain and mariner transposase fusion. (710 aa)
	Esi_0100_0076	G9a protein-human. (492 aa)
	Esi_0011_0120	MYND-type domain-containing protein. (734 aa)
	Esi_0111_0060	SET domain-containing protein. (765 aa)
	Esi_0013_0081	SET domain-containing protein. (579 aa)
	Esi_0137_0074	SET domain-containing protein. (506 aa)
	Esi_0015_0158	Uncharacterized protein. (556 aa)
	Esi_0019_0016	Ankyrin. (271 aa)
	Esi_0202_0039	Putative lipoprotein. (464 aa)
	rpl23	50S ribosomal protein L23, chloroplastic; Binds to 23S rRNA. (100 aa)
	Esi_0108_0050	Uncharacterized protein. (514 aa)
	Esi_0115_0041	Trithorax 3. (2249 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAT1	Esi_0073_0036	D7G8S8	D7G687	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.702
ACAT1	Esi_0305_0003	D7G8S8	D7FWF4	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Dihydrolipoamide succinyltransferase.	0.702
CDK	Esi_0000_0259	D8LK48	D8LB61	Possible Cdc2-related protein kinase.	Uncharacterized protein.	0.835
CDK	Esi_0000_0373	D8LK48	D8LBC4	Possible Cdc2-related protein kinase.	Uncharacterized protein.	0.588
CDK	Esi_0005_0166	D8LK48	D8LNS6	Possible Cdc2-related protein kinase.	Set domain protein.	0.535
CDK	Esi_0007_0090	D8LK48	D8LS24	Possible Cdc2-related protein kinase.	DOT1 domain-containing protein.	0.763
CDK	Esi_0010_0170	D8LK48	D8LC49	Possible Cdc2-related protein kinase.	TPR Domain containing protein.	0.588
CDK	Esi_0011_0120	D8LK48	D8LCP4	Possible Cdc2-related protein kinase.	MYND-type domain-containing protein.	0.535
CDK	Esi_0013_0081	D8LK48	D8LE87	Possible Cdc2-related protein kinase.	SET domain-containing protein.	0.535
CDK	Esi_0015_0158	D8LK48	D8LFM9	Possible Cdc2-related protein kinase.	Uncharacterized protein.	0.535
CDK	Esi_0016_0065	D8LK48	D7FLJ1	Possible Cdc2-related protein kinase.	Uncharacterized protein.	0.588
CDK	Esi_0016_0129	D8LK48	D7FLL4	Possible Cdc2-related protein kinase.	Uncharacterized protein.	0.596
CDK	Esi_0019_0016	D8LK48	D8LH49	Possible Cdc2-related protein kinase.	Ankyrin.	0.596
CDK	Esi_0020_0054	D8LK48	D8LHU3	Possible Cdc2-related protein kinase.	Uncharacterized protein.	0.588
CDK	Esi_0022_0119	D8LK48	D8LIH8	Possible Cdc2-related protein kinase.	Uncharacterized protein.	0.596
CDK	Esi_0034_0078	D8LK48	D7FY79	Possible Cdc2-related protein kinase.	DOT1 domain-containing protein.	0.763
CDK	Esi_0038_0076	D8LK48	D8LLY8	Possible Cdc2-related protein kinase.	Uncharacterized protein.	0.588
CDK	Esi_0043_0074	D8LK48	D8LN51	Possible Cdc2-related protein kinase.	Whsc1 protein.	0.596
CDK	Esi_0047_0134	D8LK48	D7G2C8	Possible Cdc2-related protein kinase.	EsV-1-1.	0.596
CDK	Esi_0048_0048	D8LK48	D7G2L8	Possible Cdc2-related protein kinase.	Uncharacterized protein.	0.596