(26 nodes) Autophagy - other network (Ectocarpus siliculosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATG2	ATG2 Autophagy-related protein homolog. (2223 aa)
	Esi_0111_0020	Serine/threonine-protein phosphatase. (320 aa)
	Atg18	Autophagy-related protein 18. (472 aa)
	Atg4	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (546 aa)
	Atg12	Ubiquitin-like protein ATG12. (231 aa)
	Esi_0110_0037	Beclin-1, putative. (650 aa)
	Esi_0115_0039	Putative phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family. (1039 aa)
	RAP	Raptor. (928 aa)
	Esi_0122_0033	Uncharacterized protein. (466 aa)
	Atg6	Beclin. (416 aa)
	Esi_0146_0052	Protein kinase domain-containing protein. (1143 aa)
	Esi_0149_0056	ATG13 domain-containing protein. (691 aa)
	Esi_0153_0048	WD40 repeat containing protein. (304 aa)
	Esi_0162_0040	Autophagy-related protein 3. (437 aa)
	PP2A	Serine/threonine-protein phosphatase. (312 aa)
	Esi_0175_0008	Uncharacterized protein. (363 aa)
	Atg7	Autophagy-related protein 7. (858 aa)
	Esi_0208_0047	Putative bis(5'-nucleosyl)-tetraphosphatase, symmetrical. (101 aa)
	Atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (515 aa)
	Esi_0265_0005	Metallophos domain-containing protein. (994 aa)
	Atg9	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (985 aa)
	Esi_0007_0111	Conserved protein. (1460 aa)
	Esi_0044_0148	Putative phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family. (1781 aa)
	Esi_0031_0152	WD_REPEATS_REGION domain-containing protein. (477 aa)
	Esi_0283_0002	Uncharacterized protein. (135 aa)
	Esi_0192_0006	Protein kinase domain-containing protein. (445 aa)

Your Current Organism:

Ectocarpus siliculosus

NCBI taxonomy Id: 2880
Other names: E. siliculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG2	Atg12	D8LE27	D7G0N6	ATG2 Autophagy-related protein homolog.	Ubiquitin-like protein ATG12.	0.525
ATG2	Atg18	D8LE27	D7G577	ATG2 Autophagy-related protein homolog.	Autophagy-related protein 18.	0.987
ATG2	Atg4	D8LE27	D7G2J0	ATG2 Autophagy-related protein homolog.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.617
ATG2	Atg5	D8LE27	D7FR86	ATG2 Autophagy-related protein homolog.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.614
ATG2	Atg6	D8LE27	D7FJA3	ATG2 Autophagy-related protein homolog.	Beclin.	0.459
ATG2	Atg7	D8LE27	D7FNV8	ATG2 Autophagy-related protein homolog.	Autophagy-related protein 7.	0.567
ATG2	Atg9	D8LE27	D7FZF2	ATG2 Autophagy-related protein homolog.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.954
ATG2	Esi_0007_0111	D8LE27	D8LRQ5	ATG2 Autophagy-related protein homolog.	Conserved protein.	0.410
ATG2	Esi_0031_0152	D8LE27	D8LL04	ATG2 Autophagy-related protein homolog.	WD_REPEATS_REGION domain-containing protein.	0.400
ATG2	Esi_0146_0052	D8LE27	D7FKN0	ATG2 Autophagy-related protein homolog.	Protein kinase domain-containing protein.	0.977
ATG2	Esi_0149_0056	D8LE27	D7FKW0	ATG2 Autophagy-related protein homolog.	ATG13 domain-containing protein.	0.629
ATG2	Esi_0162_0040	D8LE27	D7FLZ2	ATG2 Autophagy-related protein homolog.	Autophagy-related protein 3.	0.400
ATG2	Esi_0192_0006	D8LE27	D8LHF7	ATG2 Autophagy-related protein homolog.	Protein kinase domain-containing protein.	0.977
ATG2	Esi_0283_0002	D8LE27	D8LK81	ATG2 Autophagy-related protein homolog.	Uncharacterized protein.	0.400
Atg12	ATG2	D7G0N6	D8LE27	Ubiquitin-like protein ATG12.	ATG2 Autophagy-related protein homolog.	0.525
Atg12	Atg18	D7G0N6	D7G577	Ubiquitin-like protein ATG12.	Autophagy-related protein 18.	0.975
Atg12	Atg4	D7G0N6	D7G2J0	Ubiquitin-like protein ATG12.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.678
Atg12	Atg5	D7G0N6	D7FR86	Ubiquitin-like protein ATG12.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
Atg12	Atg6	D7G0N6	D7FJA3	Ubiquitin-like protein ATG12.	Beclin.	0.895
Atg12	Atg7	D7G0N6	D7FNV8	Ubiquitin-like protein ATG12.	Autophagy-related protein 7.	0.999