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maeB_1 maeB_1 fumC_1 fumC_1 fumB fumB glcB glcB ppc ppc maeB_2 maeB_2 gltA gltA SAI68343.1 SAI68343.1 sdhB sdhB sdhA sdhA sdhD sdhD sdhC_1 sdhC_1 mdh mdh mqo mqo frdB frdB SAI70899.1 SAI70899.1 sdhC_2 sdhC_2 ttdA ttdA ttdB ttdB pckG pckG sucD sucD sucC sucC aceA aceA fumC_2 fumC_2 fccA fccA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
maeB_1NADP-dependent malic enzyme. (762 aa)
fumC_1Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
fumBFumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (726 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (950 aa)
maeB_2NADP-dependent malic enzyme. (760 aa)
gltACitrate synthase; Belongs to the citrate synthase family. (434 aa)
SAI68343.1Flavinator of succinate dehydrogenase. (86 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (592 aa)
sdhDSuccinate dehydrogenase hydrophobic membrane anchor protein. (126 aa)
sdhC_1Succinate dehydrogenase cytochrome B subunit. (137 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
mqoMalate:quinone oxidoreductase. (574 aa)
frdBFumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (252 aa)
SAI70899.1Succinate dehydrogenase%2C hydrophobic membrane anchor protein. (111 aa)
sdhC_2Succinate dehydrogenase cytochrome b-556 subunit. (115 aa)
ttdAFumarate hydratase subunit alpha. (319 aa)
ttdBL-tartrate dehydratase%2C subunit B. (228 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (617 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
aceAIsocitrate lyase. (441 aa)
fumC_2Fumarate hydratase class II. (377 aa)
fccADehydrogenase. (475 aa)
Your Current Organism:
Bordetella ansorpii
NCBI taxonomy Id: 288768
Other names: B. ansorpii, strain SMC-8986
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