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pdhC pdhC fumB fumB citZ citZ acnB acnB acnA1 acnA1 ifcA_2 ifcA_2 aceE_2 aceE_2 efeU efeU odhL_2 odhL_2 odhB odhB sucA sucA aceE1 aceE1 gltA gltA SAI68343.1 SAI68343.1 sdhB sdhB sdhA sdhA sdhD sdhD sdhC_1 sdhC_1 mdh mdh icd icd icdA icdA pdhD pdhD lpd_2 lpd_2 fccA fccA fumC_2 fumC_2 acnA_2 acnA_2 sucC sucC sucD sucD pckG pckG aceE_3 aceE_3 mqo mqo citA citA frdB frdB SAI70899.1 SAI70899.1 sdhC_2 sdhC_2 frdA frdA lpd_1 lpd_1 aceF aceF aceE_1 aceE_1 fumC_1 fumC_1 odhL_1 odhL_1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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pdhC2-oxo acid dehydrogenases acyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (456 aa)
fumBFumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)
citZCitrate synthase. (264 aa)
acnBBifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (863 aa)
acnA1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (892 aa)
ifcA_2Fumarate reductase flavoprotein subunit. (468 aa)
aceE_2Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (894 aa)
efeUPermease. (281 aa)
odhL_22-oxoglutarate dehydrogenase complex%2C E3 component. (475 aa)
odhB2-oxoglutarate dehydrogenase complex%2C E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (408 aa)
sucA2-oxoglutarate dehydrogenase E1 component. (956 aa)
aceE12-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (898 aa)
gltACitrate synthase; Belongs to the citrate synthase family. (434 aa)
SAI68343.1Flavinator of succinate dehydrogenase. (86 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (592 aa)
sdhDSuccinate dehydrogenase hydrophobic membrane anchor protein. (126 aa)
sdhC_1Succinate dehydrogenase cytochrome B subunit. (137 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
icdIsocitrate dehydrogenase (NADP); Belongs to the monomeric-type IDH family. (742 aa)
icdAIsocitrate dehydrogenase. (418 aa)
pdhDPyridine nucleotide-disulfide oxidoreductase. (455 aa)
lpd_2Pyridine nucleotide-disulfide oxidoreductase. (481 aa)
fccADehydrogenase. (475 aa)
fumC_2Fumarate hydratase class II. (377 aa)
acnA_2Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (900 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (617 aa)
aceE_3Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (901 aa)
mqoMalate:quinone oxidoreductase. (574 aa)
citACitrate synthase. (272 aa)
frdBFumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (252 aa)
SAI70899.1Succinate dehydrogenase%2C hydrophobic membrane anchor protein. (111 aa)
sdhC_2Succinate dehydrogenase cytochrome b-556 subunit. (115 aa)
frdASuccinate dehydrogenase flavoprotein subunit. (591 aa)
lpd_1Dihydrolipoamide dehydrogenase. (602 aa)
aceFDihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (570 aa)
aceE_1Pyruvate dehydrogenase subunit E1. (375 aa)
fumC_1Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
odhL_12-oxoglutarate dehydrogenase complex%2C E3 component. (465 aa)
Your Current Organism:
Bordetella ansorpii
NCBI taxonomy Id: 288768
Other names: B. ansorpii, strain SMC-8986
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