STRINGSTRING
AIH03554.1 AIH03554.1 AIH03574.1 AIH03574.1 tilS tilS gid gid tgt tgt mnmG mnmG AIH03658.1 AIH03658.1 mnmA mnmA AIH03668.1 AIH03668.1 tsaD tsaD rnc rnc rph rph AIH03793.1 AIH03793.1 fmt fmt AIH03838.1 AIH03838.1 tadA tadA AIH03964.1 AIH03964.1 mnmE mnmE AIH04044.1 AIH04044.1 AIH04097.1 AIH04097.1 miaB miaB rsmH rsmH rlmN rlmN AIH04176.1 AIH04176.1 AIH04180.1 AIH04180.1 AIH04192.1 AIH04192.1 miaA miaA truA truA rsmA rsmA rimO rimO AIH04747.1 AIH04747.1 rsmI rsmI queH queH AIH04597.1 AIH04597.1 AIH04566.1 AIH04566.1 AIH04360.1 AIH04360.1 AIH04308.1 AIH04308.1 AIH03488.1 AIH03488.1 AIH03523.1 AIH03523.1 AIH03365.1 AIH03365.1 trmJ trmJ trmD trmD rimM rimM AIH03540.1 AIH03540.1 AIH03459.1 AIH03459.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIH03554.1Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)
AIH03574.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
tilSHypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (455 aa)
gidtRNA (uracil-5-)-methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (436 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (373 aa)
mnmGtRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (622 aa)
AIH03658.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (239 aa)
mnmAHypothetical protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (338 aa)
AIH03668.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
tsaDO-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (332 aa)
rncHypothetical protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (240 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (236 aa)
AIH03793.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (311 aa)
AIH03838.1RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (257 aa)
tadAAdenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (156 aa)
AIH03964.1Preprotein translocase subunit TatB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (71 aa)
mnmEtRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (466 aa)
AIH04044.1Hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (193 aa)
AIH04097.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (309 aa)
miaBDimethylallyladenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (446 aa)
rsmH16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (286 aa)
rlmN50S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (346 aa)
AIH04176.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (237 aa)
AIH04180.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
AIH04192.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (306 aa)
truAPseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (268 aa)
rsmA16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (242 aa)
rimOHypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (423 aa)
AIH04747.1Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (266 aa)
rsmIHypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (280 aa)
queHHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (188 aa)
AIH04597.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
AIH04566.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
AIH04360.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
AIH04308.1Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (307 aa)
AIH03488.1tRNA (adenine-N1)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (255 aa)
AIH03523.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
AIH03365.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (431 aa)
trmJRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (274 aa)
trmDHypothetical protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (437 aa)
rimMHypothetical protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (171 aa)
AIH03540.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
AIH03459.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SUA5 family. (197 aa)
Your Current Organism:
Thermodesulfobacterium commune
NCBI taxonomy Id: 289377
Other names: T. commune DSM 2178, Thermodesulfobacterium commune DSM 2178
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