Your Input: | |
| | groEL | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (539 aa) |
| | AIH04042.1 | Type II secretion system protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. (673 aa) |
| | mutS2 | Hypothetical protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (767 aa) |
| | AIH04028.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (436 aa) |
| | gatA | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (489 aa) |
| | gatC | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (98 aa) |
| | mnmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (466 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (291 aa) |
| | AIH03999.1 | Chromosome partitioning protein ParA; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (389 aa) |
| | AIH03997.1 | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa) |
| | AIH03988.1 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1105 aa) |
| | AIH03977.1 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1072 aa) |
| | AIH03966.1 | Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa) |
| | AIH03959.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (659 aa) |
| | AIH03958.1 | RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (370 aa) |
| | AIH03951.1 | tryptophan--tRNA ligase; Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (331 aa) |
| | pfkA | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (435 aa) |
| | tyrS | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (402 aa) |
| | hflX | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. (591 aa) |
| | cmk | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa) |
| | AIH03931.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (651 aa) |
| | AIH03929.1 | Hypothetical protein; Displays ATPase and GTPase activities. (290 aa) |
| | clpB | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (863 aa) |
| | thiL | Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (314 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (442 aa) |
| | argG | Argininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa) |
| | thrS | threonyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (647 aa) |
| | gatB | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (476 aa) |
| | AIH03899.1 | acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (295 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (879 aa) |
| | smc | Hypothetical protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1150 aa) |
| | AIH03873.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa) |
| | groS | Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (96 aa) |
| | lon | Peptidase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (788 aa) |
| | rtcA | Hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (351 aa) |
| | AIH04113.1 | Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (823 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (866 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (387 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (375 aa) |
| | murC | Hypothetical protein; Cell wall formation; Belongs to the MurCDEF family. (467 aa) |
| | murF | Hypothetical protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (467 aa) |
| | murE | Hypothetical protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (473 aa) |
| | AIH04166.1 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa) |
| | dnaJ | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (381 aa) |
| | AIH04174.1 | Hypothetical protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1742 aa) |
| | AIH04190.1 | Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (306 aa) |
| | mutL | Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (561 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (417 aa) |
| | lon-2 | DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (806 aa) |
| | clpX | ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (417 aa) |
| | AIH04209.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa) |
| | tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (399 aa) |
| | fusA | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (694 aa) |
| | AIH04244.1 | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa) |
| | AIH04250.1 | Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | AIH04259.1 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa) |
| | AIH04260.1 | Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (420 aa) |
| | cysS | cysteine--tRNA ligase; Catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (489 aa) |
| | AIH04280.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa) |
| | coaE | Hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (186 aa) |
| | AIH04309.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa) |
| | carA | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (377 aa) |
| | pheS | phenylalanine--tRNA ligase; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (337 aa) |
| | AIH04322.1 | Iron transporter FeoB; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (714 aa) |
| | pgk | Phosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (389 aa) |
| | AIH04349.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (811 aa) |
| | AIH04352.1 | Hypothetical protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (210 aa) |
| | AIH04365.1 | Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa) |
| | proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (355 aa) |
| | mutS | Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (855 aa) |
| | nadD | Hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (210 aa) |
| | AIH04402.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa) |
| | AIH04411.1 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (864 aa) |
| | recA | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (352 aa) |
| | ychF | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (367 aa) |
| | nadK | Hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (267 aa) |
| | rgy | Topoisomerase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1166 aa) |
| | AIH04484.1 | Rod shape-determining protein MreB; Functions in MreBCD complex in some organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa) |
| | AIH04487.1 | DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (803 aa) |
| | hisS | histidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa) |
| | AIH04492.1 | Iron transporter FeoB; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (672 aa) |
| | AIH04499.1 | Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa) |
| | AIH04508.1 | acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (697 aa) |
| | AIH04529.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa) |
| | cysS-2 | cysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (773 aa) |
| | fhs | Formate--tetrahydrofolate ligase; Catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (588 aa) |
| | AIH04565.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (306 aa) |
| | AIH04569.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa) |
| | AIH04574.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa) |
| | AIH04578.1 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1101 aa) |
| | AIH04589.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (255 aa) |
| | AIH04592.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa) |
| | AIH04596.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (668 aa) |
| | AIH04642.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa) |
| | AIH04644.1 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa) |
| | AIH04645.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (853 aa) |
| | birA | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (323 aa) |
| | pstB | Hypothetical protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (253 aa) |
| | ftsY | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (301 aa) |
| | engB | Ribosome biogenesis GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (197 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (565 aa) |
| | AIH04721.1 | Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa) |
| | AIH04725.1 | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa) |
| | AIH04742.1 | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (460 aa) |
| | AIH04748.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (775 aa) |
| | AIH04751.1 | Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa) |
| | tuf-2 | Elongation factor Tu; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa) |
| | hslU | ATP-dependent protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (442 aa) |
| | AIH04782.1 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa) |
| | AIH04783.1 | Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa) |
| | rtcB | tRNA-splicing ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RtcB family. (476 aa) |
| | AIH03871.1 | Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (888 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (468 aa) |
| | carB | Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1084 aa) |
| | AIH03852.1 | acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa) |
| | AIH03848.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (603 aa) |
| | AIH03824.1 | Circadian clock protein KaiC; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa) |
| | AIH03817.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa) |
| | AIH03799.1 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa) |
| | dacA | Membrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (266 aa) |
| | AIH03773.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa) |
| | AIH03772.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa) |
| | AIH03763.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa) |
| | AIH03753.1 | Cobalt ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (295 aa) |
| | AIH03739.1 | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (478 aa) |
| | era | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (310 aa) |
| | AIH03717.1 | Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa) |
| | dnaA | Hypothetical protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (448 aa) |
| | AIH03713.1 | Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (316 aa) |
| | AIH03705.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa) |
| | AIH03697.1 | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa) |
| | AIH03695.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa) |
| | coaX | Baf family transcriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (256 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (803 aa) |
| | AIH03677.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (769 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (180 aa) |
| | priA | Hypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (785 aa) |
| | AIH03664.1 | Twitching motility protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa) |
| | AIH03663.1 | Twitching motility protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa) |
| | mnmA | Hypothetical protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (338 aa) |
| | AIH03660.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa) |
| | ileS | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (933 aa) |
| | AIH03651.1 | Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa) |
| | AIH03650.1 | Hypothetical protein; May be involved in recombinational repair of damaged DNA. (546 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa) |
| | AIH03628.1 | Cobyrinic acid a,c-diamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa) |
| | tilS | Hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (455 aa) |
| | acsA | 3-hydroxypropionyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (658 aa) |
| | AIH03604.1 | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (311 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (238 aa) |
| | AIH03575.1 | Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (179 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (427 aa) |
| | AIH03562.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (600 aa) |
| | argS | arginine--tRNA ligase; Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa) |
| | dnaK | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (629 aa) |
| | der | GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (437 aa) |
| | AIH03537.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (186 aa) |
| | atpC | ATP synthase F0F1 subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (142 aa) |
| | atpD | ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (472 aa) |
| | atpG | ATP F0F1 synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (293 aa) |
| | atpA | ATP F0F1 synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (514 aa) |
| | AIH03508.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa) |
| | lysS | lysine--tRNA ligase; Class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (497 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (206 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase; Catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa) |
| | glyQ | glycyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa) |
| | glyS | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa) |
| | AIH03493.1 | Translation elongation factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (637 aa) |
| | prs | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (318 aa) |
| | ispE | Hypothetical protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (280 aa) |
| | AIH03463.1 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa) |
| | queC | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (229 aa) |
| | fliI | ATP synthase; Involved in type III protein export during flagellum assembly; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa) |
| | AIH03436.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa) |
| | AIH03433.1 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa) |
| | ffh | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (442 aa) |
| | AIH03420.1 | Carbamoyl-phosphate synthase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa) |
| | AIH03419.1 | Biotin attachment protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (690 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (628 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein MoeA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (319 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (556 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (429 aa) |
| | AIH03359.1 | Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa) |
| | AIH03353.1 | Heterodisulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa) |
| | AIH04100.1 | Phosphate starvation protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa) |
| | nrdR | ATPase; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (152 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (316 aa) |
| | AIH04088.1 | Sugar ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa) |
| | AIH04084.1 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa) |
| | AIH04071.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (577 aa) |
| | leuS | leucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (861 aa) |
