(45 nodes) De novo IMP biosynthetic process, and Tetrahydrofolate interconversion network (Emiliania huxleyi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R1BFD8_EMIHU	Uncharacterized protein. (353 aa)
	R1BI21_EMIHU	ATP-grasp domain-containing protein. (454 aa)
	purD	Phosphoribosylamine--glycine ligase. (524 aa)
	R1BLH4_EMIHU	Putative methylenetetrahydrofolate reductase. (355 aa)
	R1BZZ1_EMIHU	Methylenetetrahydrofolate dehydrogenase. (304 aa)
	R1CE07_EMIHU	Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase. (324 aa)
	R1CKT9_EMIHU	Uncharacterized protein. (161 aa)
	R1CLH6_EMIHU	Glycine cleavage system protein H. (161 aa)
	R1CZB6_EMIHU	Uncharacterized protein. (428 aa)
	GDCT1	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (384 aa)
	R1D1R7_EMIHU	Uncharacterized protein. (85 aa)
	R1D9X1_EMIHU	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase. (151 aa)
	R1DBB0_EMIHU	Uncharacterized protein. (451 aa)
	R1DH75_EMIHU	Putative methylenetetrahydrofolate reductase. (294 aa)
	R1DPF5_EMIHU	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (458 aa)
	R1DPK6_EMIHU	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (151 aa)
	R1DQV7_EMIHU	THF_DHG_CYH domain-containing protein. (167 aa)
	R1DT65_EMIHU	Uncharacterized protein. (255 aa)
	R1DUV4_EMIHU	Uncharacterized protein. (196 aa)
	R1DY87_EMIHU	ATP-grasp domain-containing protein. (507 aa)
	R1DZ60_EMIHU	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (481 aa)
	R1DZN8_EMIHU	DAO domain-containing protein. (332 aa)
	R1DZT7_EMIHU	Uncharacterized protein. (291 aa)
	R1E297_EMIHU	ATP-grasp domain-containing protein. (568 aa)
	R1E393_EMIHU	Amidophosphoribosyltransferase. (517 aa)
	R1E3F4_EMIHU	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (481 aa)
	R1EC69_EMIHU	Amidophosphoribosyltransferase. (513 aa)
	R1EEN9_EMIHU	Uncharacterized protein. (1825 aa)
	R1EFT0_EMIHU	ASL_C domain-containing protein. (82 aa)
	R1EJR3_EMIHU	ATP-grasp domain-containing protein. (559 aa)
	R1ELN4_EMIHU	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase. (581 aa)
	R1EP98_EMIHU	ATP-grasp domain-containing protein. (535 aa)
	R1EPJ4_EMIHU	Pribosyltran domain-containing protein. (287 aa)
	R1ET25_EMIHU	ATP-grasp domain-containing protein. (969 aa)
	R1EYS6_EMIHU	SAICAR_synt domain-containing protein. (370 aa)
	R1F113_EMIHU	Glutamine amidotransferase type-1 domain-containing protein. (402 aa)
	R1F7C1_EMIHU	Serine hydroxymethyltransferase. (257 aa)
	R1F7I3_EMIHU	Putative methylenetetrahydrofolate dehydrogenase. (425 aa)
	R1FD48_EMIHU	Urease accessory protein UreD. (384 aa)
	R1FJG9_EMIHU	SHMT domain-containing protein. (515 aa)
	R1FKA8_EMIHU	Sarcosine dehydrogenase. (839 aa)
	R1FLZ3_EMIHU	FGAR-AT_N domain-containing protein. (122 aa)
	R1FZ92_EMIHU	Uncharacterized protein. (71 aa)
	R1FZW1_EMIHU	Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase. (359 aa)
	R1FZW9_EMIHU	Uncharacterized protein. (1326 aa)

Your Current Organism:

Emiliania huxleyi

NCBI taxonomy Id: 2903
Other names: E. huxleyi, Emiliania huxleyi (Lohmann) W.W.Hay & H.P.Mohler, Gephyrocapsa huxleyi, Pontosphaera huxleyi

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GDCT1	R1BI21_EMIHU	R1D0A3	R1BI21	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	ATP-grasp domain-containing protein.	0.682
GDCT1	R1BLH4_EMIHU	R1D0A3	R1BLH4	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Putative methylenetetrahydrofolate reductase.	0.939
GDCT1	R1BZZ1_EMIHU	R1D0A3	R1BZZ1	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Methylenetetrahydrofolate dehydrogenase.	0.972
GDCT1	R1CE07_EMIHU	R1D0A3	R1CE07	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase.	0.738
GDCT1	R1CLH6_EMIHU	R1D0A3	R1CLH6	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Glycine cleavage system protein H.	0.949
GDCT1	R1CZB6_EMIHU	R1D0A3	R1CZB6	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Uncharacterized protein.	0.931
GDCT1	R1D1R7_EMIHU	R1D0A3	R1D1R7	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Uncharacterized protein.	0.738
GDCT1	R1D9X1_EMIHU	R1D0A3	R1D9X1	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase.	0.591
GDCT1	R1DBB0_EMIHU	R1D0A3	R1DBB0	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Uncharacterized protein.	0.952
GDCT1	R1DH75_EMIHU	R1D0A3	R1DH75	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Putative methylenetetrahydrofolate reductase.	0.939
GDCT1	R1DPF5_EMIHU	R1D0A3	R1DPF5	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.966
GDCT1	R1DPK6_EMIHU	R1D0A3	R1DPK6	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.999
GDCT1	R1DQV7_EMIHU	R1D0A3	R1DQV7	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	THF_DHG_CYH domain-containing protein.	0.738
GDCT1	R1DUV4_EMIHU	R1D0A3	R1DUV4	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Uncharacterized protein.	0.738
GDCT1	R1DY87_EMIHU	R1D0A3	R1DY87	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	ATP-grasp domain-containing protein.	0.682
GDCT1	R1DZ60_EMIHU	R1D0A3	R1DZ60	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.966
GDCT1	R1DZN8_EMIHU	R1D0A3	R1DZN8	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	DAO domain-containing protein.	0.469
GDCT1	R1E3F4_EMIHU	R1D0A3	R1E3F4	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.966
GDCT1	R1EEN9_EMIHU	R1D0A3	R1EEN9	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Uncharacterized protein.	0.931
GDCT1	R1EFT0_EMIHU	R1D0A3	R1EFT0	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	ASL_C domain-containing protein.	0.504