(18 nodes) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain network (Emiliania huxleyi)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R1D022_EMIHU	Uncharacterized protein. (600 aa)
	R1FIR2_EMIHU	2-Hacid_dh_C domain-containing protein. (381 aa)
	R1F5N1_EMIHU	Uncharacterized protein. (969 aa)
	R1ETP2_EMIHU	2-Hacid_dh_C domain-containing protein. (368 aa)
	R1EQ73_EMIHU	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (406 aa)
	R1E608_EMIHU	2-Hacid_dh_C domain-containing protein. (191 aa)
	R1DYM3_EMIHU	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa)
	R1DIJ5_EMIHU	Uncharacterized protein. (969 aa)
	R1D8F9_EMIHU	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (434 aa)
	R1FPL9_EMIHU	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (385 aa)
	R1CV42_EMIHU	2-Hacid_dh_C domain-containing protein. (202 aa)
	R1C568_EMIHU	2-Hacid_dh_C domain-containing protein. (340 aa)
	R1C492_EMIHU	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (262 aa)
	R1BQ42_EMIHU	2-Hacid_dh_C domain-containing protein. (169 aa)
	R1BI30_EMIHU	2-Hacid_dh_C domain-containing protein. (369 aa)
	R1BHZ3_EMIHU	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
	R1FQV9_EMIHU	D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
	R1FPN1_EMIHU	2-Hacid_dh_C domain-containing protein. (340 aa)

Your Current Organism:

Emiliania huxleyi

NCBI taxonomy Id: 2903
Other names: E. huxleyi, Emiliania huxleyi (Lohmann) W.W.Hay & H.P.Mohler, Gephyrocapsa huxleyi, Pontosphaera huxleyi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R1C568_EMIHU	R1FIR2_EMIHU	R1C568	R1FIR2	2-Hacid_dh_C domain-containing protein.	2-Hacid_dh_C domain-containing protein.	0.411
R1CV42_EMIHU	R1DYM3_EMIHU	R1CV42	R1DYM3	2-Hacid_dh_C domain-containing protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.521
R1D022_EMIHU	R1DYM3_EMIHU	R1D022	R1DYM3	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.435
R1DIJ5_EMIHU	R1DYM3_EMIHU	R1DIJ5	R1DYM3	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.467
R1DIJ5_EMIHU	R1FIR2_EMIHU	R1DIJ5	R1FIR2	Uncharacterized protein.	2-Hacid_dh_C domain-containing protein.	0.438
R1DYM3_EMIHU	R1CV42_EMIHU	R1DYM3	R1CV42	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	2-Hacid_dh_C domain-containing protein.	0.521
R1DYM3_EMIHU	R1D022_EMIHU	R1DYM3	R1D022	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.435
R1DYM3_EMIHU	R1DIJ5_EMIHU	R1DYM3	R1DIJ5	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.467
R1DYM3_EMIHU	R1EQ73_EMIHU	R1DYM3	R1EQ73	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.460
R1DYM3_EMIHU	R1F5N1_EMIHU	R1DYM3	R1F5N1	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.468
R1EQ73_EMIHU	R1DYM3_EMIHU	R1EQ73	R1DYM3	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.460
R1F5N1_EMIHU	R1DYM3_EMIHU	R1F5N1	R1DYM3	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.468
R1F5N1_EMIHU	R1FIR2_EMIHU	R1F5N1	R1FIR2	Uncharacterized protein.	2-Hacid_dh_C domain-containing protein.	0.438
R1FIR2_EMIHU	R1C568_EMIHU	R1FIR2	R1C568	2-Hacid_dh_C domain-containing protein.	2-Hacid_dh_C domain-containing protein.	0.411
R1FIR2_EMIHU	R1DIJ5_EMIHU	R1FIR2	R1DIJ5	2-Hacid_dh_C domain-containing protein.	Uncharacterized protein.	0.438
R1FIR2_EMIHU	R1F5N1_EMIHU	R1FIR2	R1F5N1	2-Hacid_dh_C domain-containing protein.	Uncharacterized protein.	0.438
R1FIR2_EMIHU	R1FPL9_EMIHU	R1FIR2	R1FPL9	2-Hacid_dh_C domain-containing protein.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.496
R1FIR2_EMIHU	R1FPN1_EMIHU	R1FIR2	R1FPN1	2-Hacid_dh_C domain-containing protein.	2-Hacid_dh_C domain-containing protein.	0.416
R1FPL9_EMIHU	R1FIR2_EMIHU	R1FPL9	R1FIR2	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	2-Hacid_dh_C domain-containing protein.	0.496
R1FPN1_EMIHU	R1FIR2_EMIHU	R1FPN1	R1FIR2	2-Hacid_dh_C domain-containing protein.	2-Hacid_dh_C domain-containing protein.	0.416