(9 nodes) Recycling pathway of L1 network (Emiliania huxleyi)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	CHC1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1705 aa)
	AP2M	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family. (378 aa)
	AP2M-2	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family. (433 aa)
	AP2S	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	R1DKI6_EMIHU	Uncharacterized protein. (121 aa)
	AP2A-2	Alpha-adaptin. (601 aa)
	AP2A-1	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (982 aa)
	R1EWS6_EMIHU	Uncharacterized protein. (4705 aa)
	CHC	Clathrin heavy chain. (242 aa)

Your Current Organism:

Emiliania huxleyi

NCBI taxonomy Id: 2903
Other names: E. huxleyi, Emiliania huxleyi (Lohmann) W.W.Hay & H.P.Mohler, Gephyrocapsa huxleyi, Pontosphaera huxleyi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2A-1	AP2A-2	R1EHE0	R1DLN4	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Alpha-adaptin.	0.900
AP2A-1	AP2M	R1EHE0	A0A0M3SAM9	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	0.997
AP2A-1	AP2M-2	R1EHE0	A0A0M4J7N2	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	0.997
AP2A-1	AP2S	R1EHE0	A0A0M4JKJ3	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.998
AP2A-1	CHC	R1EHE0	R1FHX8	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Clathrin heavy chain.	0.860
AP2A-1	CHC1	R1EHE0	R1G4I0	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.906
AP2A-1	R1DKI6_EMIHU	R1EHE0	R1DKI6	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Uncharacterized protein.	0.765
AP2A-2	AP2A-1	R1DLN4	R1EHE0	Alpha-adaptin.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.900
AP2A-2	AP2M	R1DLN4	A0A0M3SAM9	Alpha-adaptin.	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	0.997
AP2A-2	AP2M-2	R1DLN4	A0A0M4J7N2	Alpha-adaptin.	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	0.997
AP2A-2	AP2S	R1DLN4	A0A0M4JKJ3	Alpha-adaptin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.998
AP2A-2	CHC	R1DLN4	R1FHX8	Alpha-adaptin.	Clathrin heavy chain.	0.765
AP2A-2	CHC1	R1DLN4	R1G4I0	Alpha-adaptin.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.765
AP2A-2	R1DKI6_EMIHU	R1DLN4	R1DKI6	Alpha-adaptin.	Uncharacterized protein.	0.765
AP2M	AP2A-1	A0A0M3SAM9	R1EHE0	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.997
AP2M	AP2A-2	A0A0M3SAM9	R1DLN4	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	Alpha-adaptin.	0.997
AP2M	AP2M-2	A0A0M3SAM9	A0A0M4J7N2	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	0.900
AP2M	AP2S	A0A0M3SAM9	A0A0M4JKJ3	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
AP2M	CHC	A0A0M3SAM9	R1FHX8	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain.	0.780
AP2M	CHC1	A0A0M3SAM9	R1G4I0	Apm2, medium subunit of the adaptin 2 complex; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.853