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dnaA dnaA Clim_0071 Clim_0071 Clim_0095 Clim_0095 Clim_0175 Clim_0175 Clim_0376 Clim_0376 Clim_0391 Clim_0391 Clim_0434 Clim_0434 Clim_0484 Clim_0484 Clim_0688 Clim_0688 Clim_0689 Clim_0689 Clim_0703 Clim_0703 Clim_0772 Clim_0772 Clim_0773 Clim_0773 Clim_0855 Clim_0855 Clim_0856 Clim_0856 Clim_0857 Clim_0857 Clim_0885 Clim_0885 Clim_0919 Clim_0919 Clim_1044 Clim_1044 Clim_1116 Clim_1116 Clim_1272 Clim_1272 Clim_1282 Clim_1282 Clim_1289 Clim_1289 Clim_1292 Clim_1292 Clim_1316 Clim_1316 Clim_1531 Clim_1531 Clim_1600 Clim_1600 Clim_1620 Clim_1620 Clim_1621 Clim_1621 Clim_1673 Clim_1673 Clim_1741 Clim_1741 Clim_1742 Clim_1742 kdpA kdpA kdpB kdpB kdpC kdpC Clim_1746 Clim_1746 Clim_1806 Clim_1806 Clim_1807 Clim_1807 Clim_1809 Clim_1809 Clim_1816 Clim_1816 Clim_1817 Clim_1817 Clim_1833 Clim_1833 Clim_1842 Clim_1842 Clim_2327 Clim_2327 Clim_2350 Clim_2350 Clim_2447 Clim_2447
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (491 aa)
Clim_0071PFAM: outer membrane efflux protein; KEGG: cph:Cpha266_0096 outer membrane efflux protein. (441 aa)
Clim_0095PFAM: nitrogen regulatory protein P-II; KEGG: cch:Cag_1998 nitrogen regulatory protein P-II (GlnB, GlnK). (113 aa)
Clim_0175Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: plt:Plut_1358 PAS/PAC sensor signal transduction histidine kinase. (231 aa)
Clim_0376KEGG: cch:Cag_0501 periplasmic phosphate binding protein. (342 aa)
Clim_0391PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: cph:Cpha266_2040 protein tyrosine phosphatase. (182 aa)
Clim_0434KEGG: cph:Cpha266_1269 cytochrome c, class I. (139 aa)
Clim_0484Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: cph:Cpha266_1957 multi-sensor hybrid histidine kinase. (847 aa)
Clim_0688Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator. (691 aa)
Clim_0689Transcriptional regulator, NifA subfamily, Fis Family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cph:Cpha266_1919 DNA-binding protein fis / transcriptional regulator, Fis family. (544 aa)
Clim_0703PFAM: Nitrate reductase gamma subunit; KEGG: cph:Cpha266_0136 nitrate reductase, gamma subunit. (331 aa)
Clim_0772Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cph:Cpha266_0880 two component transcriptional regulator, winged helix family. (233 aa)
Clim_0773KEGG: cph:Cpha266_0881 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (590 aa)
Clim_0855KEGG: cph:Cpha266_0972 hydrogenase (NiFe) small subunit HydA; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Nickel-iron dehydrogenase small subunit domain protein. (361 aa)
Clim_0856PFAM: nickel-dependent hydrogenase large subunit; KEGG: cph:Cpha266_0973 nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (572 aa)
Clim_0857TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: cph:Cpha266_0974 Ni/Fe-hydrogenase, b-type cytochrome subunit. (227 aa)
Clim_0885Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; KEGG: cph:Cpha266_1801 integral membrane sensor hybrid histidine kinase. (697 aa)
Clim_0919PFAM: glutamine synthetase catalytic region; KEGG: cph:Cpha266_0832 glutamine synthetase, catalytic region. (712 aa)
Clim_1044PFAM: HpcH/HpaI aldolase; KEGG: cph:Cpha266_2198 HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (315 aa)
Clim_1116TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 factor core-binding region; sigma-54 DNA-binding domain protein; KEGG: cph:Cpha266_1547 RNA polymerase, sigma 54 subunit, RpoN. (484 aa)
Clim_1272Peptidase M15D vanX D-ala-D-ala dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (216 aa)
Clim_1282PFAM: outer membrane efflux protein; KEGG: gme:Gmet_3465 outer membrane efflux protein. (446 aa)
Clim_1289PFAM: cytochrome c class I; KEGG: cph:Cpha266_0171 C-type cytochrome, putative. (139 aa)
Clim_1292Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: cch:Cag_0439 periplasmic sensor signal transduction histidine kinase. (495 aa)
Clim_1316Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: plt:Plut_0896 malate dehydrogenase (oxaloacetate decarboxylating). (381 aa)
Clim_1531PFAM: outer membrane efflux protein; KEGG: cph:Cpha266_1665 outer membrane efflux protein. (472 aa)
Clim_1600KEGG: cph:Cpha266_1788 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; SMART: PAS domain containing protein. (1000 aa)
Clim_1620TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: cph:Cpha266_1038 phosphate binding protein. (272 aa)
Clim_1621TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: cph:Cpha266_1037 phosphate binding protein. (290 aa)
Clim_1673Protease Do; KEGG: cph:Cpha266_1855 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein. (505 aa)
Clim_1741Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: mgm:Mmc1_3600 two component, sigma54 specific, transcriptional regulator, fis family. (445 aa)
Clim_1742Multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mgm:Mmc1_3601 periplasmic sensor signal transduction histidine kinase. (608 aa)
kdpAPotassium-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (556 aa)
kdpBK+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (705 aa)
kdpCPotassium-transporting ATPase; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (195 aa)
Clim_1746Osmosensitive K channel His kinase sensor; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; Osmosensitive K channel His kinase sensor; KEGG: sfu:Sfum_2617 osmosensitive K+ channel His kinase sensor. (553 aa)
Clim_1806PFAM: cytochrome c oxidase subunit I; KEGG: cch:Cag_1356 cytochrome-cbb3 oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family. (461 aa)
Clim_1807TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; PFAM: cytochrome C oxidase mono-heme subunit/FixO; KEGG: cch:Cag_1357 cytochrome-c oxidase FixO chain. (223 aa)
Clim_1809PFAM: cytochrome c class I; KEGG: cch:Cag_1358 probable cb-type cytochrome c oxidase subunit III. (153 aa)
Clim_1816PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: cph:Cpha266_0700 cytochrome bd ubiquinol oxidase, subunit I. (451 aa)
Clim_1817KEGG: cph:Cpha266_0699 cytochrome d ubiquinol oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II. (337 aa)
Clim_1833Sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cph:Cpha266_1832 sigma54 specific transcriptional regulator, Fis family. (433 aa)
Clim_1842PFAM: polysaccharide export protein; KEGG: cph:Cpha266_1823 polysaccharide export protein. (379 aa)
Clim_2327PFAM: cytochrome c class I; KEGG: cph:Cpha266_0171 C-type cytochrome, putative. (136 aa)
Clim_2350PFAM: outer membrane efflux protein; KEGG: cph:Cpha266_0183 outer membrane efflux protein. (441 aa)
Clim_2447PFAM: Alkaline phosphatase; KEGG: cph:Cpha266_2693 alkaline phosphatase; Belongs to the alkaline phosphatase family. (486 aa)
Your Current Organism:
Chlorobium limicola
NCBI taxonomy Id: 290315
Other names: C. limicola DSM 245, Chlorobium limicola 6330, Chlorobium limicola DSM 245, Chlorobium limicola DSMZ 245(T), Chlorobium limicola str. DSM 245, Chlorobium limicola strain DSM 245
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