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CKO_00013 | Hypothetical protein; KEGG: ecc:c4596 1.6e-284 ilvB; acetolactate synthase isozyme I large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (564 aa) | ||||
dsdA | Hypothetical protein; KEGG: ece:Z3628 6.2e-219 dsdA; D-serine dehydratase (deaminase) K01753; COG: COG3048 D-serine dehydratase; Psort location: Cytoplasmic, score:8.96. (442 aa) | ||||
CKO_00107 | Hypothetical protein; KEGG: stm:STM3901 2.1e-282 ilvG; acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.96. (548 aa) | ||||
ilvA | Hypothetical protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (515 aa) | ||||
glyA | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa) | ||||
iscS | Hypothetical protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (411 aa) | ||||
CKO_00345 | Hypothetical protein; KEGG: spt:SPA0410 3.9e-240 eutB; ethanolamine ammonia-lyase heavy chain K03735; COG: COG4303 Ethanolamine ammonia-lyase, large subunit. (453 aa) | ||||
eutC | Hypothetical protein; KEGG: stm:STM2457 1.0e-138 eutC; ethanolamine ammonia-lyase, light chain K03736; COG: COG4302 Ethanolamine ammonia-lyase, small subunit; Psort location: Cytoplasmic, score:8.96; Belongs to the EutC family. (301 aa) | ||||
CKO_00371 | Hypothetical protein; KEGG: nwi:Nwi_0881 1.1e-26 transcriptional regulatory protein GntR family K00825; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (430 aa) | ||||
CKO_00409 | Hypothetical protein; KEGG: stm:STM2405 6.4e-240 indolepyruvate decarboxylase K01568; COG: COG3961 Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes. (551 aa) | ||||
CKO_00421 | Hypothetical protein; KEGG: eco:b2379 2.5e-215 yfdZ; putative PLP-dependent aminotransferase; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score:8.96. (412 aa) | ||||
CKO_00505 | Hypothetical protein; KEGG: sdy:SDY_2486 1.9e-217 putative aminotransferase K00812; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score:8.96. (405 aa) | ||||
menD | Hypothetical protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (556 aa) | ||||
hisC | Hypothetical protein; KEGG: ece:Z3183 4.1e-174 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Psort location: Cytoplasmic, score:8.96; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (359 aa) | ||||
CKO_00794 | Hypothetical protein; KEGG: sec:SC2050 7.6e-79 pduE; propanediol utilization: dehydratase, small subunit K06122; COG: COG4910 Propanediol dehydratase, small subunit. (172 aa) | ||||
CKO_00795 | Hypothetical protein; KEGG: stm:STM2041 2.4e-107 pduD; Propanediol utilization: dehydratase, medium subunit K06121; COG: COG4909 Propanediol dehydratase, large subunit; Psort location: Cytoplasmic, score:8.96. (224 aa) | ||||
CKO_00796 | Hypothetical protein; KEGG: stm:STM2040 2.0e-291 pduC; glycerol dehydratase large subunit K06120; COG: COG4909 Propanediol dehydratase, large subunit; Psort location: Cytoplasmic, score:8.96. (554 aa) | ||||
CKO_00859 | Hypothetical protein; KEGG: ava:Ava_4834 1.1e-184 beta-ketoacyl synthase K01845; COG: COG3321 Polyketide synthase modules and related proteins. (3208 aa) | ||||
CKO_00860 | Hypothetical protein; KEGG: ava:Ava_4834 7.3e-125 beta-ketoacyl synthase K01845; COG: COG3321 Polyketide synthase modules and related proteins; Psort location: Cytoplasmic, score:9.26. (869 aa) | ||||
CKO_00867 | Hypothetical protein; KEGG: rha:RHA1_ro06103 2.1e-198 non-ribosomal peptide synthetase K01779:K01897; COG: COG1020 Non-ribosomal peptide synthetase modules and related proteins; Psort location: CytoplasmicMembrane, score:8.46. (1598 aa) | ||||
CKO_00869 | Hypothetical protein; KEGG: eci:UTI89_C2214 0. putative peptide synthetase K01932; COG: COG1020 Non-ribosomal peptide synthetase modules and related proteins; Psort location: CytoplasmicMembrane, score:8.46. (2166 aa) | ||||
CKO_00870 | Hypothetical protein; KEGG: eci:UTI89_C2214 0. putative peptide synthetase K01932; COG: COG3321 Polyketide synthase modules and related proteins. (2177 aa) | ||||
CKO_00911 | Hypothetical protein; KEGG: bur:Bcep18194_B0672 4.1e-190 non-ribosomal peptide synthetase modules K01776; COG: COG3433 Aryl carrier domain; Psort location: CytoplasmicMembrane, score:8.46. (1836 aa) | ||||
CKO_01194 | Hypothetical protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (356 aa) | ||||
CKO_01248 | Hypothetical protein; KEGG: bur:Bcep18194_B0672 4.1e-190 non-ribosomal peptide synthetase modules K01776; COG: COG3433 Aryl carrier domain. (2035 aa) | ||||
CKO_01425 | Hypothetical protein; KEGG: ecp:ECP_1403 0. probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (1174 aa) | ||||
CKO_01477 | Hypothetical protein; KEGG: eci:UTI89_C1658 5.5e-218 ydcR; hypothetical protein YdcR K00811; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: Cytoplasmic, score:9.26. (469 aa) | ||||
CKO_01629 | Hypothetical protein; KEGG: ece:Z2627 6.4e-185 malY; enzyme that may degrade or block biosynthesis of endogenous mal inducer, probably aminotrasferase K01760; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. (390 aa) | ||||
CKO_01707 | Hypothetical protein; KEGG: plu:plu0523 1.2e-149 unnamed protein product; similar to cystathionine gamma-lyase K01758; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. (381 aa) | ||||
sufS | Hypothetical protein; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. (406 aa) | ||||
astC | Hypothetical protein; Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily. (406 aa) | ||||
CKO_01962 | Hypothetical protein; KEGG: sec:SC1148 3.0e-107 pabC; 4-amino-4-deoxychorismate lyase K02619; COG: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (269 aa) | ||||
CKO_02121 | Hypothetical protein; KEGG: reh:H16_B1359 1.3e-06 paaE2; phenylacetic acid degradation protein E,flavodoxin reductase; COG: COG0633 Ferredoxin. (355 aa) | ||||
CKO_02139 | Hypothetical protein; KEGG: ecj:JW0911 2.0e-204 aspC; aspartate aminotransferase, PLP-dependent K00813; COG: COG1448 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score:9.26. (396 aa) | ||||
serC | Hypothetical protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa) | ||||
CKO_02209 | Hypothetical protein; KEGG: ecc:c1004 4.9e-297 poxB; pyruvate dehydrogenase K00156; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.96; Belongs to the TPP enzyme family. (572 aa) | ||||
bioF | Hypothetical protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (384 aa) | ||||
bioA | Hypothetical protein; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (429 aa) | ||||
glmS-2 | Hypothetical protein; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (149 aa) | ||||
glmE | Hypothetical protein; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (481 aa) | ||||
CKO_02434 | Hypothetical protein; KEGG: sec:SC0740 0. sucA; 2-oxoglutarate dehydrogenase (decarboxylase component) K00164; COG: COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes; Psort location: Cytoplasmic, score:9.26. (933 aa) | ||||
CKO_02518 | Hypothetical protein; KEGG: stt:t2223 1.6e-149 cobD; threonine-phosphate decarboxylase K04720; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Psort location: Cytoplasmic, score:8.96. (364 aa) | ||||
CKO_02559 | Hypothetical protein; KEGG: sec:SC0634 8.8e-188 ybdL; putative aminotransferase K00812; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase. (389 aa) | ||||
CKO_02575 | Hypothetical protein; KEGG: stm:STM0588 0. entF; enterobactin synthetase, component F (nonribosomal peptide synthetase) K02364; COG: COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases; Psort location: CytoplasmicMembrane, score:8.46. (1294 aa) | ||||
CKO_02700 | Hypothetical protein; KEGG: rha:RHA1_ro05556 2.4e-98 transcriptional regulator/aminotransferase; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (475 aa) | ||||
dxs | Hypothetical protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (620 aa) | ||||
CKO_03055 | Hypothetical protein; KEGG: eco:b3939 2.8e-198 metB, met-1, met1; cystathionine gamma-synthase K01739; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. (386 aa) | ||||
CKO_03090 | COG: COG2258 Uncharacterized protein conserved in bacteria. (223 aa) | ||||
btuF | Hypothetical protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (266 aa) | ||||
hemL | Hypothetical protein; KEGG: sbo:SBO_0143 1.2e-183 hemL; glutamate-1-semialdehyde aminotransferase K01845; COG: COG0001 Glutamate-1-semialdehyde aminotransferase; Psort location: Cytoplasmic, score:8.96. (352 aa) | ||||
CKO_03301 | Hypothetical protein; KEGG: ssn:SSO_0084 8.0e-297 ilvI; acetolactate synthase isozyme III large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (574 aa) | ||||
CKO_03314 | Hypothetical protein; COG: COG4143 ABC-type thiamine transport system, periplasmic component; Psort location: Periplasmic, score:10.00. (331 aa) | ||||
CKO_03383 | Hypothetical protein; KEGG: sbo:SBO_0003 1.6e-213 thrC; threonine synthase K01733; COG: COG0498 Threonine synthase; Psort location: Cytoplasmic, score:8.96. (428 aa) | ||||
CKO_03450 | Hypothetical protein; KEGG: bur:Bcep18194_B1266 1.4e-79 transcriptional regulator, GntR family with aminotransferase activity K00825; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: Cytoplasmic, score:9.26. (470 aa) | ||||
CKO_03454 | Hypothetical protein; KEGG: sfl:SF3053 3.6e-159 metC; cystathionine beta-lyase K01760; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.26. (396 aa) | ||||
CKO_03854 | Hypothetical protein; KEGG: eci:UTI89_C4630 0. 2-oxoglutarate dehydrogenase E1 component K00164; COG: COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes; Psort location: Cytoplasmic, score:9.26. (914 aa) | ||||
CKO_03855 | Hypothetical protein; KEGG: eco:b4054 8.6e-197 tyrB; tyrosine aminotransferase, tyrosine repressible K00832; COG: COG1448 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score:9.97. (397 aa) | ||||
CKO_03857 | Hypothetical protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (359 aa) | ||||
CKO_03902 | Hypothetical protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1247 aa) | ||||
CKO_03993 | Hypothetical protein; KEGG: ypm:YP_1136 4.9e-297 ilvB1; putative thiamine pyrophosphate-dependent protein K03336; COG: COG3962 Acetolactate synthase; Belongs to the TPP enzyme family. (636 aa) | ||||
CKO_04009 | Hypothetical protein; KEGG: ecj:JW2637 1.5e-208 gabT; 4-aminobutyrate aminotransferase, PLP-dependent K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa) | ||||
CKO_04020 | Hypothetical protein; KEGG: eci:UTI89_C3030 1.7e-184 hypothetical protein K00375; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: Cytoplasmic, score:9.26. (450 aa) | ||||
CKO_04174 | Hypothetical protein; KEGG: ssn:SSO_2967 3.1e-192 cysteine sulfinate desulfinase; COG: COG0520 Selenocysteine lyase; Psort location: Cytoplasmic, score:8.96. (401 aa) | ||||
lysA | Hypothetical protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) | ||||
CKO_04260 | Hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. (310 aa) | ||||
CKO_04327 | Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. (234 aa) | ||||
CKO_04402 | Hypothetical protein; KEGG: ecc:c3742 8.1e-201 metC; cystathionine beta-lyase K01760; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.26. (421 aa) | ||||
patA | Hypothetical protein; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (503 aa) | ||||
CKO_04517 | Hypothetical protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (329 aa) | ||||
CKO_04539 | Hypothetical protein; KEGG: ecc:c1175 1.0e-184 putative aminotransferase K00842; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; Psort location: Cytoplasmic, score:8.96. (390 aa) | ||||
argD | Hypothetical protein; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa) | ||||
CKO_04796 | Hypothetical protein; KEGG: tfu:Tfu_0632 7.7e-08 cystathionine gamma-synthase K01739; COG: NOG06470 non supervised orthologous group. (360 aa) | ||||
CKO_04801 | Hypothetical protein; KEGG: ctc:CTC02513 0.00019 alr; alanine racemase K01775; COG: COG3457 Predicted amino acid racemase; Psort location: Cytoplasmic, score:8.96. (387 aa) | ||||
CKO_04838 | Hypothetical protein; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (797 aa) | ||||
CKO_04847 | Hypothetical protein; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (815 aa) | ||||
CKO_04884 | Hypothetical protein; KEGG: eca:ECA2053 6.6e-167 gabT, goaG; 4-aminobutyrate aminotransferase K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa) | ||||
CKO_04984 | Hypothetical protein; KEGG: tde:TDE2200 6.7e-126 megL; methionine gamma-lyase K01761; COG: COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; Psort location: Cytoplasmic, score:9.97. (398 aa) | ||||
CKO_05030 | Hypothetical protein; KEGG: eci:UTI89_C4114 1.3e-216 avtA; valine--pyruvate aminotransferase K00835; COG: COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase; Psort location: Cytoplasmic, score:8.96. (430 aa) | ||||
kbl | Hypothetical protein; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (398 aa) |