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zwf zwf CKO_00756 CKO_00756 fcl fcl gmd gmd CKO_00435 CKO_00435 hldD hldD CKO_04956 CKO_04956 asd asd CKO_04789 CKO_04789 aroE aroE cysI cysI garR garR CKO_03385 CKO_03385 dapB dapB CKO_03333 CKO_03333 dxr dxr CKO_03131 CKO_03131 CKO_03054 CKO_03054 proA proA CKO_02747 CKO_02747 CKO_02214 CKO_02214 CKO_02047 CKO_02047 CKO_01800 CKO_01800 CKO_01610 CKO_01610 CKO_01450 CKO_01450 CKO_01293 CKO_01293 hemA hemA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
zwfHypothetical protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)
CKO_00756Hypothetical protein; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)
fclHypothetical protein; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (321 aa)
gmdHypothetical protein; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (373 aa)
CKO_00435Hypothetical protein; KEGG: eci:UTI89_C1638 1.5e-137 glyceraldehyde 3-phosphate dehydrogenase A K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score:9.97. (333 aa)
hldDHypothetical protein; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (310 aa)
CKO_04956Hypothetical protein; KEGG: ecs:ECs4372 9.0e-234 glutathione oxidoreductase K00383; COG: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Psort location: Cytoplasmic, score:9.97. (450 aa)
asdHypothetical protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (368 aa)
CKO_04789Hypothetical protein; KEGG: stm:STM3474 0. nirB; nitrite reductase, large subunit K00362; COG: COG1251 NAD(P)H-nitrite reductase; Psort location: Cytoplasmic, score:9.97; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (847 aa)
aroEHypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa)
cysIHypothetical protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (570 aa)
garRHypothetical protein; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily. (296 aa)
CKO_03385Hypothetical protein; KEGG: sec:SC0002 0. thrA; aspartokinase I K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. (820 aa)
dapBHypothetical protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa)
CKO_03333Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (159 aa)
dxrHypothetical protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). (398 aa)
CKO_03131Hypothetical protein; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily. (307 aa)
CKO_03054Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. (810 aa)
proAHypothetical protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (417 aa)
CKO_02747Hypothetical protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
CKO_02214Hypothetical protein; KEGG: eci:UTI89_C0871 8.5e-174 ybjS; hypothetical protein YbjS K00067; COG: COG0451 Nucleoside-diphosphate-sugar epimerases. (337 aa)
CKO_02047Hypothetical protein; KEGG: mav:MAV_3849 3.8e-29 wrbA; NAD(P)H:quinone oxidoreductase, type IV K00355; COG: COG0655 Multimeric flavodoxin WrbA. (198 aa)
CKO_01800Hypothetical protein; KEGG: stt:t1169 8.8e-172 gapA; glyceraldehyde 3-phosphate dehydrogenase A K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score:9.97. (331 aa)
CKO_01610Hypothetical protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa)
CKO_01450Hypothetical protein; KEGG: ssn:SSO_1725 1.5e-160 gapC; glyceraldehyde-3-phosphate dehydrogenase K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score:9.97. (333 aa)
CKO_01293Hypothetical protein; KEGG: eca:ECA2991 0. nasB; nitrite reductase [NAD(P)H] large subunit K00362; COG: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Psort location: Cytoplasmic, score:9.26; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (1355 aa)
hemAHypothetical protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (418 aa)
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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