STRINGSTRING
ispH ispH CKO_03338 CKO_03338 leuC leuC CKO_03252 CKO_03252 erpA erpA CKO_03145 CKO_03145 CKO_03118 CKO_03118 CKO_03117 CKO_03117 CKO_03116 CKO_03116 CKO_03042 CKO_03042 CKO_02997 CKO_02997 thiC thiC CKO_02828 CKO_02828 CKO_00513 CKO_00513 nuoI nuoI CKO_00534 CKO_00534 CKO_00539 CKO_00539 CKO_02175 CKO_02175 CKO_02177 CKO_02177 hcp hcp CKO_02207 CKO_02207 rlmC rlmC rimO rimO CKO_02286 CKO_02286 dinG dinG moaA-2 moaA-2 bioB bioB CKO_02363 CKO_02363 CKO_02656 CKO_02656 nadA nadA CKO_02424 CKO_02424 CKO_02435 CKO_02435 miaB miaB lipA lipA napA napA CKO_00570 CKO_00570 CKO_00571 CKO_00571 CKO_00633 CKO_00633 CKO_00672 CKO_00672 CKO_00782 CKO_00782 CKO_00783 CKO_00783 edd edd CKO_01166 CKO_01166 CKO_01225 CKO_01225 moaA moaA queH queH CKO_01263 CKO_01263 CKO_01293 CKO_01293 CKO_01294 CKO_01294 CKO_01301 CKO_01301 CKO_01358 CKO_01358 CKO_01409 CKO_01409 ttcA ttcA CKO_01425 CKO_01425 CKO_01503 CKO_01503 CKO_01514 CKO_01514 CKO_01581 CKO_01581 CKO_01582 CKO_01582 CKO_01583 CKO_01583 CKO_01623 CKO_01623 rnfB rnfB rnfC rnfC nth nth CKO_01665 CKO_01665 CKO_01696 CKO_01696 CKO_01698 CKO_01698 CKO_01699 CKO_01699 CKO_01716 CKO_01716 CKO_01717 CKO_01717 CKO_04789 CKO_04789 CKO_04790 CKO_04790 feoC feoC nfuA nfuA CKO_05031 CKO_05031 CKO_01722 CKO_01722 CKO_01821 CKO_01821 CKO_02071 CKO_02071 CKO_02121 CKO_02121 CKO_02169 CKO_02169 CKO_00022 CKO_00022 ilvD ilvD CKO_00220 CKO_00220 iscR iscR iscS iscS CKO_00252 CKO_00252 CKO_00253 CKO_00253 CKO_00256 CKO_00256 rlmN rlmN ispG ispG CKO_00325 CKO_00325 nuoB nuoB CKO_00511 CKO_00511 CKO_00512 CKO_00512 queG queG CKO_03679 CKO_03679 CKO_03688 CKO_03688 CKO_03749 CKO_03749 CKO_03772 CKO_03772 CKO_03800 CKO_03800 CKO_03803 CKO_03803 CKO_03811 CKO_03811 CKO_03827 CKO_03827 CKO_04068 CKO_04068 CKO_04074 CKO_04074 CKO_04075 CKO_04075 CKO_04080 CKO_04080 cysI cysI CKO_04122 CKO_04122 queE queE rlmD rlmD CKO_04154 CKO_04154 CKO_04246 CKO_04246 CKO_04331 CKO_04331 CKO_04336 CKO_04336 CKO_04380 CKO_04380 CKO_04390 CKO_04390 CKO_04391 CKO_04391 CKO_04409 CKO_04409 CKO_04451 CKO_04451 CKO_04512 CKO_04512 CKO_04553 CKO_04553 CKO_04554 CKO_04554 CKO_04593 CKO_04593 CKO_04616 CKO_04616 CKO_04620 CKO_04620 CKO_04622 CKO_04622 CKO_04744 CKO_04744 CKO_03654 CKO_03654 CKO_03582 CKO_03582 CKO_03512 CKO_03512 CKO_03511 CKO_03511 CKO_03459 CKO_03459 CKO_03429 CKO_03429 CKO_03412 CKO_03412
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ispHHypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. (316 aa)
CKO_03338Hypothetical protein; Could be a 3Fe-4S cluster-containing protein. (95 aa)
leuCHypothetical protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa)
CKO_03252Hypothetical protein; KEGG: sec:SC0157 0. acnB; aconitate hydratase 2 K01682; COG: COG1049 Aconitase B; Psort location: Cytoplasmic, score:8.96; Belongs to the aconitase/IPM isomerase family. (874 aa)
erpAHypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. (114 aa)
CKO_03145Hypothetical protein; KEGG: ecj:JW3838 8.6e-229 hemN; coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen-independent K02495; COG: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Psort location: Cytoplasmic, score:9.97; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (457 aa)
CKO_03118Hypothetical protein; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa)
CKO_03117Hypothetical protein; KEGG: sty:STY3839 0. fdoG; formate dehydrogenase-O, major subunit K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.44; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (804 aa)
CKO_03116Hypothetical protein; KEGG: ecs:ECs4820 6.0e-102 formate dehydrogenase-O major subunit K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76. (195 aa)
CKO_03042Hypothetical protein; KEGG: stm:STM4115 2.8e-88 pflC; putative pyruvate formate lyase activating enzyme 2 K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score:9.97. (213 aa)
CKO_02997Hypothetical protein; KEGG: mac:MA0154 8.9e-13 bioB; biotin synthase K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (376 aa)
thiCHypothetical protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (631 aa)
CKO_02828Hypothetical protein; KEGG: ecc:c0453 9.0e-250 prpD, mmgE; 2-methylcitrate dehydratase K01720; COG: COG2079 Uncharacterized protein involved in propionate catabolism. (486 aa)
CKO_00513Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (911 aa)
nuoIHypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
CKO_00534Hypothetical protein; KEGG: stm:STM2286 1.6e-211 glpC; sn-glycerol-3-phosphate dehydrogenase (anaerobic), K-small subunit K00113; COG: COG0247 Fe-S oxidoreductase. (396 aa)
CKO_00539Hypothetical protein; KEGG: ype:YPO3116 1.4e-08 ddhD, ascD, rfbI; CDP-6-deoxy-delta-3,4-glucoseen reductase K00523; COG: COG0633 Ferredoxin; Psort location: Cytoplasmic, score:8.96. (84 aa)
CKO_02175Hypothetical protein; KEGG: ecp:ECP_0909 2.8e-49 anaerobic dimethyl sulfoxide reductase, subunit B K07307; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1. (99 aa)
CKO_02177Hypothetical protein; KEGG: sec:SC0918 0. dmsA; anaerobic dimethyl sulfoxide reductase, subunit A K07306; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (814 aa)
hcpHypothetical protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (562 aa)
CKO_02207Hypothetical protein; KEGG: stm:STM0936 4.4e-154 hcr; NADH oxidoreductase for hcp gene product; COG: COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Psort location: Cytoplasmic, score:8.96. (311 aa)
rlmCHypothetical protein; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily. (376 aa)
rimOHypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (280 aa)
CKO_02286Hypothetical protein; KEGG: stm:STM0844 3.2e-151 pflE; putative pyruvate formate lyase activating enzyme K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score:9.97. (299 aa)
dinGHypothetical protein; DNA-dependent ATPase and 5'-3' DNA helicase. (725 aa)
moaA-2Hypothetical protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (340 aa)
bioBHypothetical protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (346 aa)
CKO_02363Hypothetical protein; KEGG: ecp:ECP_0784 0. aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score:9.26. (752 aa)
CKO_02656Hypothetical protein; KEGG: eci:UTI89_C4034 2.1e-218 chuW; putative oxygen independent coproporphyrinogen III oxidase K02495; COG: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Psort location: Cytoplasmic, score:9.97. (445 aa)
nadAHypothetical protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (348 aa)
CKO_02424Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (550 aa)
CKO_02435Hypothetical protein; KEGG: spt:SPA2008 8.3e-128 sdhB; succinate dehydrogenase iron-sulfur protein K00240; COG: COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (238 aa)
miaBHypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (488 aa)
lipAHypothetical protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa)
napAHypothetical protein; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa)
CKO_00570Hypothetical protein; KEGG: eci:UTI89_C2483 6.6e-112 napG; ferredoxin-type protein, subunit of nitrate reductase, periplasmic K02573; COG: COG1145 Ferredoxin. (214 aa)
CKO_00571Hypothetical protein; KEGG: eci:UTI89_C2482 3.3e-149 napH; ferredoxin-type protein K02574; COG: COG0348 Polyferredoxin; Psort location: CytoplasmicMembrane, score:10.00. (287 aa)
CKO_00633Hypothetical protein; KEGG: stm:STM2196 1.0e-184 L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (433 aa)
CKO_00672Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (369 aa)
CKO_00782Hypothetical protein; COG: COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein. (184 aa)
CKO_00783Hypothetical protein; KEGG: eci:UTI89_C1819 3.8e-38 rnfC; electron transport complex protein RnfC K03615; COG: COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC; Psort location: Cytoplasmic, score:8.96. (451 aa)
eddHypothetical protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa)
CKO_01166Hypothetical protein; KEGG: stm:STM1826 2.7e-234 sdaA; L-serine deaminase I/L-threonine deaminase I K01752; COG: COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (473 aa)
CKO_01225Hypothetical protein; KEGG: bur:Bcep18194_C6997 0. oxidoreductase alpha (molybdopterin) subunit K00122; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (762 aa)
moaAHypothetical protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (328 aa)
queHHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (237 aa)
CKO_01263Hypothetical protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (183 aa)
CKO_01293Hypothetical protein; KEGG: eca:ECA2991 0. nasB; nitrite reductase [NAD(P)H] large subunit K00362; COG: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Psort location: Cytoplasmic, score:9.26; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (1355 aa)
CKO_01294Hypothetical protein; KEGG: eca:ECA2990 1.7e-264 nasA; nitrate reductase K00372; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (870 aa)
CKO_01301Hypothetical protein; KEGG: spt:SPA1109 0. narG; respiratory nitrate reductase 1 alpha chain K00370; COG: COG5013 Nitrate reductase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1247 aa)
CKO_01358Hypothetical protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa)
CKO_01409Hypothetical protein; KEGG: eci:UTI89_C3860 2.5e-08 crp; CRP-cAMP transcriptional dual regulator K00924; COG: COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; Psort location: Cytoplasmic, score:9.97. (276 aa)
ttcAHypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (311 aa)
CKO_01425Hypothetical protein; KEGG: ecp:ECP_1403 0. probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (1174 aa)
CKO_01503Hypothetical protein; KEGG: stm:STM1577 0. narZ; nitrate reductase alpha chain K08345; COG: COG5013 Nitrate reductase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1246 aa)
CKO_01514Hypothetical protein; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (294 aa)
CKO_01581Hypothetical protein; KEGG: stm:STM1499 0. putative dimethyl sulphoxide reductase, chain A1 K07309; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (809 aa)
CKO_01582Hypothetical protein; KEGG: stm:STM1498 0. putative dimethyl sulphoxide reductase K07310; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (811 aa)
CKO_01583Hypothetical protein; KEGG: ecp:ECP_0909 2.4e-114 anaerobic dimethyl sulfoxide reductase, subunit B K07307; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1; Psort location: CytoplasmicMembrane, score:7.88. (205 aa)
CKO_01623Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa)
rnfBHypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (192 aa)
rnfCHypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (705 aa)
nthHypothetical protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa)
CKO_01665Hypothetical protein; KEGG: ama:AM1083 5.9e-08 grxC1; glutaredoxin 3 K03676; COG: COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. (115 aa)
CKO_01696Hypothetical protein; KEGG: eci:UTI89_C1863 3.7e-118 putative oxidoreductase Fe-S subunit K00178; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1; Psort location: Cytoplasmic, score:9.97. (243 aa)
CKO_01698Hypothetical protein; KEGG: eci:UTI89_C1865 0. ydhV; hypothetical protein YdhV K03738; COG: COG2414 Aldehyde:ferredoxin oxidoreductase. (708 aa)
CKO_01699Hypothetical protein; KEGG: eci:UTI89_C1866 1.1e-107 ydhY; putative ferredoxin-like protein YdhY K00199; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1; Psort location: CytoplasmicMembrane, score:9.82. (208 aa)
CKO_01716Hypothetical protein; COG: COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component. (495 aa)
CKO_01717Hypothetical protein; COG: COG0316 Uncharacterized conserved protein; Belongs to the HesB/IscA family. (122 aa)
CKO_04789Hypothetical protein; KEGG: stm:STM3474 0. nirB; nitrite reductase, large subunit K00362; COG: COG1251 NAD(P)H-nitrite reductase; Psort location: Cytoplasmic, score:9.97; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (847 aa)
CKO_04790Hypothetical protein; KEGG: sfl:SF3385 3.8e-52 nirD; nitrite reductase (NAD(P)H) subunit K00363; COG: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Psort location: Cytoplasmic, score:9.97. (108 aa)
feoCHypothetical protein; May function as a transcriptional regulator that controls feoABC expression. (78 aa)
nfuAHypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (191 aa)
CKO_05031Hypothetical protein; KEGG: eci:UTI89_C4115 4.7e-70 ysaA, yiaI; putative electron transport protein YsaA K00122; COG: COG1142 Fe-S-cluster-containing hydrogenase components 2; Psort location: Cytoplasmic, score:9.97. (157 aa)
CKO_01722Hypothetical protein; KEGG: eci:UTI89_C1879 0. ydiJ; hypothetical protein YdiJ; COG: COG0247 Fe-S oxidoreductase; Psort location: Cytoplasmic, score:8.96. (1018 aa)
CKO_01821Hypothetical protein; KEGG: eca:ECA1250 0. fdhF; formate dehydrogenase H K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.44; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (715 aa)
CKO_02071Hypothetical protein; KEGG: eci:UTI89_C1055 6.3e-146 yccM; putative electron transport protein YccM K00168; COG: COG0348 Polyferredoxin; Psort location: CytoplasmicMembrane, score:10.00. (368 aa)
CKO_02121Hypothetical protein; KEGG: reh:H16_B1359 1.3e-06 paaE2; phenylacetic acid degradation protein E,flavodoxin reductase; COG: COG0633 Ferredoxin. (355 aa)
CKO_02169Hypothetical protein; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (255 aa)
CKO_00022Hypothetical protein; KEGG: syg:sync_2368 3.1e-16 arylsulfatase regulator; COG: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); Psort location: Cytoplasmic, score:8.96. (338 aa)
ilvDHypothetical protein; KEGG: eci:UTI89_C4327 0. ilvD; dihydroxy-acid dehydratase K01687; COG: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (602 aa)
CKO_00220Hypothetical protein; KEGG: mmp:MMP1692 4.7e-06 vhuB; polyferredoxin, associated with F420-non-reducing hydrogenase; COG: COG1145 Ferredoxin. (86 aa)
iscRHypothetical protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (163 aa)
iscSHypothetical protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (411 aa)
CKO_00252Hypothetical protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa)
CKO_00253Hypothetical protein; COG: COG0316 Uncharacterized conserved protein; Psort location: Cytoplasmic, score:8.96; Belongs to the HesB/IscA family. (70 aa)
CKO_00256Hypothetical protein; KEGG: eci:UTI89_C2847 7.5e-56 fdx; ferredoxin, 2Fe-2S K04755; COG: COG0633 Ferredoxin; Psort location: Cytoplasmic, score:8.96. (111 aa)
rlmNHypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (388 aa)
ispGHypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (372 aa)
CKO_00325Hypothetical protein; KEGG: eci:UTI89_C2794 1.1e-226 aegA, yffG; putative oxidoreductase Fe-S subunit K00264; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score:9.97. (471 aa)
nuoBHypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa)
CKO_00511Hypothetical protein; KEGG: sty:STY2555 2.2e-88 nuoE; NADH dehydrogenase I chain E K00334; COG: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; Psort location: Cytoplasmic, score:9.26. (166 aa)
CKO_00512Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (445 aa)
queGHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (379 aa)
CKO_03679Hypothetical protein; KEGG: stm:STM4342 2.4e-130 frdB; fumarate reductase, anaerobic, Fe-S protein subunit K00245; COG: COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Psort location: Cytoplasmic, score:8.96. (244 aa)
CKO_03688Hypothetical protein; KEGG: eci:UTI89_C4744 1.3e-168 yjeK; hypothetical protein YjeK K01843; COG: COG1509 Lysine 2,3-aminomutase; Psort location: Cytoplasmic, score:8.96. (342 aa)
CKO_03749Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa)
CKO_03772Hypothetical protein; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (282 aa)
CKO_03800Hypothetical protein; KEGG: stm:STM4285 1.7e-72 fdhF; formate dehydrogenase K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.44. (139 aa)
CKO_03803Hypothetical protein; KEGG: ecj:JW4040 4.1e-300 fdhF; formate dehydrogenase-H, selenopolypeptide subunit K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (559 aa)
CKO_03811Hypothetical protein; KEGG: vfi:VF1552 4.8e-77 thiosulfate reductase electron transport subunit K04014; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1. (223 aa)
CKO_03827Hypothetical protein; KEGG: eci:UTI89_C3737 1.8e-06 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG0789 Predicted transcriptional regulators; Psort location: Cytoplasmic, score:8.96. (152 aa)
CKO_04068Hypothetical protein; KEGG: eci:UTI89_C3075 6.1e-93 hydN; electron transport protein HydN K05796; COG: COG1142 Fe-S-cluster-containing hydrogenase components 2; Psort location: Cytoplasmic, score:9.97. (195 aa)
CKO_04074Hypothetical protein; KEGG: eci:UTI89_C3082 1.6e-131 hycG; formate hydrogenlyase subunit 7; COG: COG3260 Ni,Fe-hydrogenase III small subunit; Psort location: Cytoplasmic, score:8.96. (255 aa)
CKO_04075Hypothetical protein; KEGG: eci:UTI89_C3083 8.9e-92 hycF; formate hydrogenlyase subunit 6; COG: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); Psort location: Cytoplasmic, score:8.96. (180 aa)
CKO_04080Hypothetical protein; KEGG: eci:UTI89_C3087 2.3e-86 hycB; formate hydrogenlyase subunit 2; COG: COG1142 Fe-S-cluster-containing hydrogenase components 2; Psort location: Cytoplasmic, score:8.96. (170 aa)
cysIHypothetical protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (570 aa)
CKO_04122Hypothetical protein; Could be a 3Fe-4S cluster-containing protein. (86 aa)
queEHypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (223 aa)
rlmDHypothetical protein; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (432 aa)
CKO_04154Hypothetical protein; KEGG: stm:STM2971 1.4e-235 sdaB; L-serine dehydratase (L-threonine deaminase 2) K01752; COG: COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
CKO_04246Hypothetical protein; KEGG: eci:UTI89_C0330 6.3e-249 ykgF; putative electron transport protein YkgF K08263; COG: COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain; Psort location: Cytoplasmic, score:8.96. (475 aa)
CKO_04331Hypothetical protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (378 aa)
CKO_04336Hypothetical protein; Adenine glycosylase active on G-A mispairs. (383 aa)
CKO_04380Hypothetical protein; KEGG: eci:UTI89_C1715 3.3e-236 ydeP; hypothetical protein YdeP K00122; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (762 aa)
CKO_04390Hypothetical protein; KEGG: eci:UTI89_C3418 8.6e-158 hybA; hydrogenase-2 operon protein HybA precursor K00396; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1; Psort location: Periplasmic, score:10.00. (289 aa)
CKO_04391Hypothetical protein; KEGG: sty:STY3321 1.0e-202 hyb0; hydrogenase small chain K06282; COG: COG1740 Ni,Fe-hydrogenase I small subunit; Psort location: Periplasmic, score:9.76. (372 aa)
CKO_04409KEGG: eci:UTI89_C3435 0. hypothetical protein; COG: COG1032 Fe-S oxidoreductase. (723 aa)
CKO_04451Hypothetical protein; KEGG: ecs:ECs3944 6.4e-153 L-tartrate dehydratase subunit A K03779; COG: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain. (303 aa)
CKO_04512Hypothetical protein; KEGG: spt:SPA3109 1.8e-221 tdcG; L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa)
CKO_04553Hypothetical protein; KEGG: ecp:ECP_3246 5.8e-175 putative protease YhbU precursor K08303; COG: COG0826 Collagenase and related proteases; Psort location: Cytoplasmic, score:8.96. (331 aa)
CKO_04554Hypothetical protein; KEGG: eci:UTI89_C3586 4.7e-150 yhbV; hypothetical protein YhbV K01423; COG: COG0826 Collagenase and related proteases; Psort location: Cytoplasmic, score:8.96. (298 aa)
CKO_04593Hypothetical protein; COG: COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family. (97 aa)
CKO_04616Hypothetical protein; KEGG: eci:UTI89_C3647 7.0e-60 yhcC; hypothetical protein; COG: COG1242 Predicted Fe-S oxidoreductase. (124 aa)
CKO_04620Hypothetical protein; KEGG: sbo:SBO_3170 0. gltB; glutamate synthase, large subunit K00265; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score:8.96. (1498 aa)
CKO_04622Hypothetical protein; KEGG: sty:STY3511 2.6e-250 gltD; glutamate synthase (NADPH) small chain K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score:9.97. (472 aa)
CKO_04744KEGG: ppr:PBPRA2525 0.0043 hypothetical nitrate reductase large subunit K00372; COG: COG2906 Bacterioferritin-associated ferredoxin; Psort location: Cytoplasmic, score:8.96. (64 aa)
CKO_03654Hypothetical protein; COG: COG1959 Predicted transcriptional regulator. (125 aa)
CKO_03582Hypothetical protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (154 aa)
CKO_03512Hypothetical protein; KEGG: syg:sync_2368 0.0053 arylsulfatase regulator; COG: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); Psort location: Cytoplasmic, score:8.96. (462 aa)
CKO_03511Hypothetical protein; COG: COG0535 Predicted Fe-S oxidoreductases. (370 aa)
CKO_03459Hypothetical protein; KEGG: eci:UTI89_C5044 2.4e-114 yjiL; hypothetical protein YjiL K04111; COG: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain). (255 aa)
CKO_03429Hypothetical protein; KEGG: gbe:GbCGDNIH1_2380 0.00064 ferric hydroxamate reductase FhuF K00521; COG: COG4114 Uncharacterized Fe-S protein; Psort location: Cytoplasmic, score:8.96. (262 aa)
CKO_03412Hypothetical protein; KEGG: vfi:VFA0962 1.2e-71 pyruvate formate-lyase activating enzyme K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score:9.97. (284 aa)
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.