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nuoB nuoB nadA nadA CKO_02424 CKO_02424 rlmN rlmN CKO_01293 CKO_01293 CKO_01294 CKO_01294 CKO_01301 CKO_01301 CKO_01358 CKO_01358 ttcA ttcA ispG ispG CKO_00511 CKO_00511 CKO_00512 CKO_00512 CKO_00513 CKO_00513 nuoI nuoI napA napA CKO_00633 CKO_00633 CKO_00672 CKO_00672 CKO_00783 CKO_00783 edd edd CKO_01166 CKO_01166 moaA moaA queH queH CKO_01503 CKO_01503 CKO_01425 CKO_01425 CKO_01514 CKO_01514 CKO_01581 CKO_01581 CKO_01582 CKO_01582 CKO_01623 CKO_01623 rnfB rnfB rnfC rnfC nth nth nfuA nfuA feoC feoC CKO_04789 CKO_04789 CKO_04512 CKO_04512 CKO_04409 CKO_04409 CKO_04391 CKO_04391 CKO_04331 CKO_04331 CKO_04154 CKO_04154 rlmD rlmD queE queE CKO_04122 CKO_04122 cysI cysI CKO_03800 CKO_03800 CKO_03772 CKO_03772 CKO_03749 CKO_03749 CKO_03688 CKO_03688 CKO_03679 CKO_03679 queG queG ispH ispH CKO_03338 CKO_03338 leuC leuC CKO_03252 CKO_03252 erpA erpA CKO_03145 CKO_03145 CKO_03118 CKO_03118 CKO_03116 CKO_03116 CKO_02997 CKO_02997 thiC thiC lipA lipA miaB miaB CKO_02435 CKO_02435 CKO_01665 CKO_01665 CKO_01821 CKO_01821 CKO_02169 CKO_02169 CKO_02177 CKO_02177 hcp hcp CKO_02207 CKO_02207 rlmC rlmC rimO rimO dinG dinG iscR iscR ilvD ilvD iscS iscS moaA-2 moaA-2 bioB bioB
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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nuoBHypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa)
nadAHypothetical protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (348 aa)
CKO_02424Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (550 aa)
rlmNHypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (388 aa)
CKO_01293Hypothetical protein; KEGG: eca:ECA2991 0. nasB; nitrite reductase [NAD(P)H] large subunit K00362; COG: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Psort location: Cytoplasmic, score:9.26; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (1355 aa)
CKO_01294Hypothetical protein; KEGG: eca:ECA2990 1.7e-264 nasA; nitrate reductase K00372; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (870 aa)
CKO_01301Hypothetical protein; KEGG: spt:SPA1109 0. narG; respiratory nitrate reductase 1 alpha chain K00370; COG: COG5013 Nitrate reductase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1247 aa)
CKO_01358Hypothetical protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa)
ttcAHypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (311 aa)
ispGHypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (372 aa)
CKO_00511Hypothetical protein; KEGG: sty:STY2555 2.2e-88 nuoE; NADH dehydrogenase I chain E K00334; COG: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; Psort location: Cytoplasmic, score:9.26. (166 aa)
CKO_00512Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (445 aa)
CKO_00513Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (911 aa)
nuoIHypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
napAHypothetical protein; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa)
CKO_00633Hypothetical protein; KEGG: stm:STM2196 1.0e-184 L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (433 aa)
CKO_00672Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (369 aa)
CKO_00783Hypothetical protein; KEGG: eci:UTI89_C1819 3.8e-38 rnfC; electron transport complex protein RnfC K03615; COG: COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC; Psort location: Cytoplasmic, score:8.96. (451 aa)
eddHypothetical protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa)
CKO_01166Hypothetical protein; KEGG: stm:STM1826 2.7e-234 sdaA; L-serine deaminase I/L-threonine deaminase I K01752; COG: COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (473 aa)
moaAHypothetical protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (328 aa)
queHHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (237 aa)
CKO_01503Hypothetical protein; KEGG: stm:STM1577 0. narZ; nitrate reductase alpha chain K08345; COG: COG5013 Nitrate reductase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1246 aa)
CKO_01425Hypothetical protein; KEGG: ecp:ECP_1403 0. probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (1174 aa)
CKO_01514Hypothetical protein; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (294 aa)
CKO_01581Hypothetical protein; KEGG: stm:STM1499 0. putative dimethyl sulphoxide reductase, chain A1 K07309; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (809 aa)
CKO_01582Hypothetical protein; KEGG: stm:STM1498 0. putative dimethyl sulphoxide reductase K07310; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (811 aa)
CKO_01623Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa)
rnfBHypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (192 aa)
rnfCHypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (705 aa)
nthHypothetical protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa)
nfuAHypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (191 aa)
feoCHypothetical protein; May function as a transcriptional regulator that controls feoABC expression. (78 aa)
CKO_04789Hypothetical protein; KEGG: stm:STM3474 0. nirB; nitrite reductase, large subunit K00362; COG: COG1251 NAD(P)H-nitrite reductase; Psort location: Cytoplasmic, score:9.97; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (847 aa)
CKO_04512Hypothetical protein; KEGG: spt:SPA3109 1.8e-221 tdcG; L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa)
CKO_04409KEGG: eci:UTI89_C3435 0. hypothetical protein; COG: COG1032 Fe-S oxidoreductase. (723 aa)
CKO_04391Hypothetical protein; KEGG: sty:STY3321 1.0e-202 hyb0; hydrogenase small chain K06282; COG: COG1740 Ni,Fe-hydrogenase I small subunit; Psort location: Periplasmic, score:9.76. (372 aa)
CKO_04331Hypothetical protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (378 aa)
CKO_04154Hypothetical protein; KEGG: stm:STM2971 1.4e-235 sdaB; L-serine dehydratase (L-threonine deaminase 2) K01752; COG: COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
rlmDHypothetical protein; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (432 aa)
queEHypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (223 aa)
CKO_04122Hypothetical protein; Could be a 3Fe-4S cluster-containing protein. (86 aa)
cysIHypothetical protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (570 aa)
CKO_03800Hypothetical protein; KEGG: stm:STM4285 1.7e-72 fdhF; formate dehydrogenase K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.44. (139 aa)
CKO_03772Hypothetical protein; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (282 aa)
CKO_03749Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa)
CKO_03688Hypothetical protein; KEGG: eci:UTI89_C4744 1.3e-168 yjeK; hypothetical protein YjeK K01843; COG: COG1509 Lysine 2,3-aminomutase; Psort location: Cytoplasmic, score:8.96. (342 aa)
CKO_03679Hypothetical protein; KEGG: stm:STM4342 2.4e-130 frdB; fumarate reductase, anaerobic, Fe-S protein subunit K00245; COG: COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Psort location: Cytoplasmic, score:8.96. (244 aa)
queGHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (379 aa)
ispHHypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. (316 aa)
CKO_03338Hypothetical protein; Could be a 3Fe-4S cluster-containing protein. (95 aa)
leuCHypothetical protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa)
CKO_03252Hypothetical protein; KEGG: sec:SC0157 0. acnB; aconitate hydratase 2 K01682; COG: COG1049 Aconitase B; Psort location: Cytoplasmic, score:8.96; Belongs to the aconitase/IPM isomerase family. (874 aa)
erpAHypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. (114 aa)
CKO_03145Hypothetical protein; KEGG: ecj:JW3838 8.6e-229 hemN; coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen-independent K02495; COG: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Psort location: Cytoplasmic, score:9.97; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (457 aa)
CKO_03118Hypothetical protein; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa)
CKO_03116Hypothetical protein; KEGG: ecs:ECs4820 6.0e-102 formate dehydrogenase-O major subunit K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76. (195 aa)
CKO_02997Hypothetical protein; KEGG: mac:MA0154 8.9e-13 bioB; biotin synthase K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (376 aa)
thiCHypothetical protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (631 aa)
lipAHypothetical protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa)
miaBHypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (488 aa)
CKO_02435Hypothetical protein; KEGG: spt:SPA2008 8.3e-128 sdhB; succinate dehydrogenase iron-sulfur protein K00240; COG: COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (238 aa)
CKO_01665Hypothetical protein; KEGG: ama:AM1083 5.9e-08 grxC1; glutaredoxin 3 K03676; COG: COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. (115 aa)
CKO_01821Hypothetical protein; KEGG: eca:ECA1250 0. fdhF; formate dehydrogenase H K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.44; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (715 aa)
CKO_02169Hypothetical protein; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (255 aa)
CKO_02177Hypothetical protein; KEGG: sec:SC0918 0. dmsA; anaerobic dimethyl sulfoxide reductase, subunit A K07306; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (814 aa)
hcpHypothetical protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (562 aa)
CKO_02207Hypothetical protein; KEGG: stm:STM0936 4.4e-154 hcr; NADH oxidoreductase for hcp gene product; COG: COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Psort location: Cytoplasmic, score:8.96. (311 aa)
rlmCHypothetical protein; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily. (376 aa)
rimOHypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (280 aa)
dinGHypothetical protein; DNA-dependent ATPase and 5'-3' DNA helicase. (725 aa)
iscRHypothetical protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (163 aa)
ilvDHypothetical protein; KEGG: eci:UTI89_C4327 0. ilvD; dihydroxy-acid dehydratase K01687; COG: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (602 aa)
iscSHypothetical protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (411 aa)
moaA-2Hypothetical protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (340 aa)
bioBHypothetical protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (346 aa)
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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