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CKO_00011 CKO_00011 CKO_00013 CKO_00013 CKO_00107 CKO_00107 CKO_00108 CKO_00108 ilvE ilvE ilvD ilvD ilvC ilvC acpS acpS CKO_00857 CKO_00857 CKO_02736 CKO_02736 acpH acpH coaA coaA panB panB panC panC panD panD coaE coaE CKO_03300 CKO_03300 CKO_03301 CKO_03301 CKO_04136 CKO_04136 CKO_04925 CKO_04925 coaD coaD CKO_05096 CKO_05096
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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CKO_00011Hypothetical protein; KEGG: sty:STY3987 7.8e-45 ilvN; acetolactate synthase small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score:8.96. (96 aa)
CKO_00013Hypothetical protein; KEGG: ecc:c4596 1.6e-284 ilvB; acetolactate synthase isozyme I large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (564 aa)
CKO_00107Hypothetical protein; KEGG: stm:STM3901 2.1e-282 ilvG; acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.96. (548 aa)
CKO_00108Hypothetical protein; KEGG: sec:SC3807 4.1e-39 ilvM; acetolactate synthase II, small subunit K01653; COG: COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit; Psort location: Cytoplasmic, score:8.96. (87 aa)
ilvEHypothetical protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (309 aa)
ilvDHypothetical protein; KEGG: eci:UTI89_C4327 0. ilvD; dihydroxy-acid dehydratase K01687; COG: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (602 aa)
ilvCHypothetical protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (491 aa)
acpSHypothetical protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (126 aa)
CKO_00857Hypothetical protein; KEGG: syn:slr0495 6.5e-18 lipopeptide antibiotics iturin a biosynthesis protein K01005; COG: COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (244 aa)
CKO_02736Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (303 aa)
acpHHypothetical protein; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. (211 aa)
coaAHypothetical protein; KEGG: ecc:c4933 2.6e-165 coaA; pantothenate kinase K00867; COG: COG1072 Panthothenate kinase. (322 aa)
panBHypothetical protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (263 aa)
panCHypothetical protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (307 aa)
panDHypothetical protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa)
coaEHypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa)
CKO_03300Hypothetical protein; KEGG: eci:UTI89_C0086 3.5e-81 ilvH; acetolactate synthase III, valine sensitive, small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score:8.96. (173 aa)
CKO_03301Hypothetical protein; KEGG: ssn:SSO_0084 8.0e-297 ilvI; acetolactate synthase isozyme III large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (574 aa)
CKO_04136Hypothetical protein; KEGG: pha:PSHAa0740 1.5e-59 mazG; nucleoside triphosphate pyrophosphohydrolase, non-specific K02428; COG: COG1694 Predicted pyrophosphatase; Psort location: Cytoplasmic, score:8.96. (263 aa)
CKO_04925Hypothetical protein; KEGG: sty:STY4228 1.1e-84 4'-phosphopantetheinyl transferase K06133; COG: COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (195 aa)
coaDHypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)
CKO_05096Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (434 aa)
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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