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| | CKO_00145 | Hypothetical protein; KEGG: stm:STM3936 4.6e-182 hemX; uroporphyrinogen III methylase K02496; COG: COG2959 Uncharacterized enzyme of heme biosynthesis. (393 aa) |
| | CKO_00146 | Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (246 aa) |
| | hemC | Hypothetical protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (318 aa) |
| | dapF | Hypothetical protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (275 aa) |
| | CKO_00172 | Hypothetical protein; KEGG: stm:STM3967 3.7e-134 dlhH; putative dienelactone hydrolase family K01061; COG: COG0412 Dienelactone hydrolase and related enzymes. (269 aa) |
| | fadA | Hypothetical protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (389 aa) |
| | fadB | Hypothetical protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (729 aa) |
| | glyA | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa) |
| | CKO_00241 | Hypothetical protein; KEGG: eco:b3879 0.0025 yihR; predicted aldose-1-epimerase K01785; COG: COG2017 Galactose mutarotase and related enzymes. (280 aa) |
| | CKO_00261 | Hypothetical protein; KEGG: ssn:SSO_2603 2.3e-132 sseA; putative thiosulfate sulfurtransferase K01011; COG: COG2897 Rhodanese-related sulfurtransferase. (284 aa) |
| | dapA | Hypothetical protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | dapE | Hypothetical protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa) |
| | CKO_00329 | Hypothetical protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa) |
| | tal | Hypothetical protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa) |
| | CKO_00332 | Hypothetical protein; KEGG: sty:STY2709 0. maeB; NADP-dependent malate dehydrogenase (decarboxylating) K00029; COG: COG0280 Phosphotransacetylase. (759 aa) |
| | CKO_00340 | Hypothetical protein; KEGG: rru:Rru_A0914 9.8e-102 aldehyde dehydrogenase K04021; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:8.96. (467 aa) |
| | CKO_00342 | Hypothetical protein; KEGG: eci:UTI89_C2777 1.7e-182 eutG, yffV; ethanolamine utilization protein EutG iron-containing alcohol dehydrogenase K04022; COG: COG1454 Alcohol dehydrogenase, class IV; Psort location: Cytoplasmic, score:9.26. (395 aa) |
| | CKO_00379 | Hypothetical protein; KEGG: sty:STY2666 1.0e-163 cysK; cysteine synthase A K01738; COG: COG0031 Cysteine synthase; Psort location: Cytoplasmic, score:8.96; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa) |
| | gltX | Hypothetical protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (471 aa) |
| | glk | Hypothetical protein; KEGG: stm:STM2403 5.7e-161 glk; glucokinase K00845; COG: COG0837 Glucokinase; Psort location: Cytoplasmic, score:9.97; Belongs to the bacterial glucokinase family. (321 aa) |
| | CKO_00435 | Hypothetical protein; KEGG: eci:UTI89_C1638 1.5e-137 glyceraldehyde 3-phosphate dehydrogenase A K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score:9.97. (333 aa) |
| | fadI | Hypothetical protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (436 aa) |
| | fadJ | Hypothetical protein; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa) |
| | accD | Hypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (304 aa) |
| | ubiX | Hypothetical protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (189 aa) |
| | CKO_00489 | Hypothetical protein; KEGG: sty:STY2574 4.4e-58 putative sugar phosphotransferase component II A K02821; COG: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); Psort location: Cytoplasmic, score:9.97. (136 aa) |
| | CKO_00490 | Hypothetical protein; KEGG: spt:SPA0521 9.6e-40 putative sugar phosphotransferase component II B K02822; COG: COG3414 Phosphotransferase system, galactitol-specific IIB component. (92 aa) |
| | CKO_00491 | Hypothetical protein; KEGG: mcp:MCAP_0590 2.1e-90 PTS system, IIBC component, putative K02822:K03475; COG: COG3037 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score:10.00. (463 aa) |
| | CKO_00492 | Hypothetical protein; KEGG: sec:SC2342 5.8e-136 tktN; putative transketolase K00615; COG: COG3959 Transketolase, N-terminal subunit; Psort location: Cytoplasmic, score:8.96. (276 aa) |
| | CKO_00493 | Hypothetical protein; KEGG: stm:STM2340 7.1e-154 putative transketolase K00615; COG: COG3958 Transketolase, C-terminal subunit; Psort location: Cytoplasmic, score:8.96. (317 aa) |
| | CKO_00497 | Hypothetical protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (709 aa) |
| | ackA | Hypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | CKO_00545 | Hypothetical protein; KEGG: eci:UTI89_C2506 4.2e-181 atoB; acetyl-CoA acetyltransferase K00626; COG: COG0183 Acetyl-CoA acetyltransferase; Psort location: Cytoplasmic, score:9.97; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | CKO_00547 | Hypothetical protein; KEGG: eci:UTI89_C2504 1.0e-106 atoA; acetate CoA-transferase beta subunit K01035; COG: COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit; Psort location: Cytoplasmic, score:8.96. (216 aa) |
| | CKO_00548 | Hypothetical protein; KEGG: eco:b2221 1.1e-102 atoD; acetyl-CoA:acetoacetyl-CoA transferase alpha subunit K01034; COG: COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit. (226 aa) |
| | mqo | Hypothetical protein; KEGG: eci:UTI89_C2490 3.3e-259 mqo; malate dehydrogenase K00116; COG: COG0579 Predicted dehydrogenase. (553 aa) |
| | napA | Hypothetical protein; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa) |
| | CKO_00572 | Hypothetical protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (156 aa) |
| | CKO_00615 | Hypothetical protein; KEGG: spt:SPA0647 2.8e-278 fruA; PTS system, fructose-specific IIBC component K02769:K02770; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score:10.00. (563 aa) |
| | CKO_00636 | Hypothetical protein; Serine hydrolase involved in the detoxification of formaldehyde. (278 aa) |
| | CKO_00651 | Hypothetical protein; KEGG: stt:t0677 3.7e-180 putative gentisate 1,2-dioxygenase K00450; COG: COG3435 Gentisate 1,2-dioxygenase. (345 aa) |
| | CKO_00652 | Hypothetical protein; KEGG: reh:H16_B0874 3.0e-91 fumarylpyruvate hydrolase K01557; COG: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (233 aa) |
| | CKO_00653 | Hypothetical protein; KEGG: pen:PSEEN2595 5.8e-65 mhbI; maleylpyruvate isomerase K01800; COG: COG0625 Glutathione S-transferase. (215 aa) |
| | CKO_00654 | Hypothetical protein; KEGG: stt:t0680 1.8e-210 putative n-hydroxybenzoate hydroxylase K00480; COG: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; Psort location: Cytoplasmic, score:8.96. (397 aa) |
| | dld | Hypothetical protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (600 aa) |
| | CKO_00687 | Hypothetical protein; KEGG: eco:b2097 1.6e-181 fbaB, dhnA; fructose-bisphosphate aldolase class I K01623; COG: COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes. (350 aa) |
| | CKO_00756 | Hypothetical protein; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa) |
| | CKO_00862 | Hypothetical protein; KEGG: ecc:c2467 1.0e-152 bhbD; putative 3-hydroxyacyl-CoA dehydrogenase K00074; COG: COG1250 3-hydroxyacyl-CoA dehydrogenase. (289 aa) |
| | CKO_00871 | Hypothetical protein; KEGG: eci:UTI89_C2212 1.0e-264 putative amidase K01426; COG: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases. (487 aa) |
| | CKO_00944 | Hypothetical protein; KEGG: eca:ECA0203 2.5e-103 hemB; delta-aminolevulinic acid dehydratase K01698; COG: COG0113 Delta-aminolevulinic acid dehydratase; Psort location: Cytoplasmic, score:8.96; Belongs to the ALAD family. (285 aa) |
| | CKO_00970 | Hypothetical protein; KEGG: ssn:SSO_3604 9.3e-200 iucD; lysine:N6-hydroxylase K03897; COG: COG3486 Lysine/ornithine N-monooxygenase; Psort location: CytoplasmicMembrane, score:9.96. (444 aa) |
| | CKO_00971 | KEGG: ecc:c3625 0. iucC; iucC protein K03895; COG: COG4264 Siderophore synthetase component. (577 aa) |
| | CKO_00972 | Hypothetical protein; KEGG: sbo:SBO_4338 2.2e-166 iucB; siderophore biosynthesis protein K03896; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins. (315 aa) |
| | CKO_00974 | Hypothetical protein; KEGG: sfl:SF3715 1.5e-238 iucA; aerobactin synthetase subunit alpha K03894; COG: COG4264 Siderophore synthetase component. (465 aa) |
| | CKO_01110 | Hypothetical protein; KEGG: spt:SPA0981 2.6e-243 pykA; pyruvate kinase A K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score:8.96. (480 aa) |
| | zwf | Hypothetical protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | edd | Hypothetical protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa) |
| | CKO_01116 | Hypothetical protein; KEGG: stm:STM1884 6.3e-107 eda; keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase K01570:K01625:K01650; COG: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; Psort location: Cytoplasmic, score:9.97. (213 aa) |
| | prs | Hypothetical protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa) |
| | hemA | Hypothetical protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (418 aa) |
| | CKO_01293 | Hypothetical protein; KEGG: eca:ECA2991 0. nasB; nitrite reductase [NAD(P)H] large subunit K00362; COG: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Psort location: Cytoplasmic, score:9.26; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (1355 aa) |
| | CKO_01294 | Hypothetical protein; KEGG: eca:ECA2990 1.7e-264 nasA; nitrate reductase K00372; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (870 aa) |
| | CKO_01301 | Hypothetical protein; KEGG: spt:SPA1109 0. narG; respiratory nitrate reductase 1 alpha chain K00370; COG: COG5013 Nitrate reductase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1247 aa) |
| | CKO_01302 | Hypothetical protein; KEGG: stt:t1672 2.2e-285 narH; respiratory nitrate reductase 1 beta chain K00371; COG: COG1140 Nitrate reductase beta subunit; Psort location: Cytoplasmic, score:9.26. (511 aa) |
| | CKO_01304 | Hypothetical protein; KEGG: stm:STM1761 1.0e-115 narI; nitrate reductase gamma chain K00374; COG: COG2181 Nitrate reductase gamma subunit; Psort location: CytoplasmicMembrane, score:10.00. (225 aa) |
| | CKO_01318 | Hypothetical protein; KEGG: stm:STM1749 0. adhE; alcohol dehydrogenase / acetaldehyde dehydrogenase K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (891 aa) |
| | CKO_01358 | Hypothetical protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa) |
| | CKO_01425 | Hypothetical protein; KEGG: ecp:ECP_1403 0. probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (1174 aa) |
| | CKO_01429 | Hypothetical protein; KEGG: spt:SPA1239 2.2e-168 ldhA; D-lactate dehydrogenase K03778; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score:9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa) |
| | CKO_01438 | Hypothetical protein; KEGG: eco:b1406 1.7e-127 ydbC; predicted oxidoreductase, NAD(P)-binding; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: Cytoplasmic, score:8.96. (289 aa) |
| | CKO_01448 | Hypothetical protein; KEGG: ece:Z2306 9.3e-232 aldA; aldehyde dehydrogenase, NAD-linked K07248:K00138; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.97. (471 aa) |
| | CKO_01450 | Hypothetical protein; KEGG: ssn:SSO_1725 1.5e-160 gapC; glyceraldehyde-3-phosphate dehydrogenase K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score:9.97. (333 aa) |
| | CKO_01455 | Hypothetical protein; KEGG: stm:STM1627 7.5e-198 alcohol dehydrogenase class III K00001:K00121; COG: COG1062 Zn-dependent alcohol dehydrogenases, class III; Psort location: Cytoplasmic, score:9.97; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (372 aa) |
| | patD | Hypothetical protein; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (474 aa) |
| | CKO_01500 | Hypothetical protein; KEGG: eci:UTI89_C1683 3.1e-114 narV; respiratory nitrate reductase 2 gamma chain K08347; COG: COG2181 Nitrate reductase gamma subunit; Psort location: CytoplasmicMembrane, score:10.00. (226 aa) |
| | CKO_01502 | Hypothetical protein; KEGG: spt:SPA1290 3.7e-283 narY; respiratory nitrate reductase 2 beta chain K08346; COG: COG1140 Nitrate reductase beta subunit; Psort location: Cytoplasmic, score:9.26. (514 aa) |
| | CKO_01503 | Hypothetical protein; KEGG: stm:STM1577 0. narZ; nitrate reductase alpha chain K08345; COG: COG5013 Nitrate reductase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1246 aa) |
| | eno | Hypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (428 aa) |
| | CKO_01545 | Hypothetical protein; KEGG: stm:STM1524 1.6e-213 yneI; putative succinate-semialdehyde dehydrogenase K08324; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.97. (462 aa) |
| | ldh | Hypothetical protein; Catalyzes the conversion of lactate to pyruvate. (338 aa) |
| | fumC | Hypothetical protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (482 aa) |
| | CKO_01623 | Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa) |
| | pdxH | Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (218 aa) |
| | CKO_01662 | Hypothetical protein; KEGG: ecj:JW1642 1.6e-181 nemA; N-ethylmaleimide reductase, FMN-linked; COG: COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; Psort location: Cytoplasmic, score:8.96. (365 aa) |
| | CKO_01695 | Hypothetical protein; KEGG: mag:amb2674 1.7e-08 cytochrome b subunit of formate dehydrogenase K00127; COG: COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein); Psort location: CytoplasmicMembrane, score:10.00. (261 aa) |
| | CKO_01701 | Hypothetical protein; COG: NOG13889 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96. (69 aa) |
| | CKO_01709 | Hypothetical protein; KEGG: stm:STM1378 2.2e-237 pykF; pyruvate kinase I (formerly F), fructose stimulated K00873; COG: COG0469 Pyruvate kinase. (470 aa) |
| | CKO_01725 | Hypothetical protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa) |
| | CKO_01748 | Hypothetical protein; KEGG: stm:STM1326 2.9e-148 pfkB; 6-phosphofructokinase II K00850; COG: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Psort location: Cytoplasmic, score:9.26; Belongs to the carbohydrate kinase PfkB family. (309 aa) |
| | CKO_01789 | Hypothetical protein; KEGG: spt:SPA1545 3.0e-235 gdhA; NADP-specific glutamate dehydrogenase K00262; COG: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Psort location: Cytoplasmic, score:9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa) |
| | CKO_01800 | Hypothetical protein; KEGG: stt:t1169 8.8e-172 gapA; glyceraldehyde 3-phosphate dehydrogenase A K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score:9.97. (331 aa) |
| | CKO_01801 | Hypothetical protein; KEGG: tbd:Tbd_2730 3.0e-36 dihydroxy-acid dehydratase K01687; COG: COG0676 Uncharacterized enzymes related to aldose 1-epimerase; Psort location: Cytoplasmic, score:8.96; Belongs to the glucose-6-phosphate 1-epimerase family. (294 aa) |
| | CKO_01828 | Hypothetical protein; KEGG: eci:UTI89_C2076 0. bisZ; trimethylamine-N-oxide reductase 2 precursor K07812; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:10.00. (821 aa) |
| | CKO_01829 | Hypothetical protein; KEGG: eci:UTI89_C2480 7.4e-33 napC; cytochrome c protein, subunit of nitrate reductase, periplasmic K02569; COG: COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit; Psort location: CytoplasmicMembrane, score:8.02. (320 aa) |
| | CKO_01835 | Hypothetical protein; KEGG: stm:STM1238 5.2e-222 icdA; isocitrate dehydrogenase K00031; COG: COG0538 Isocitrate dehydrogenases; Psort location: Cytoplasmic, score:9.97. (416 aa) |
| | ghrA | Hypothetical protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. (312 aa) |
| | CKO_02049 | Hypothetical protein; KEGG: ecp:ECP_1001 2.2e-200 glucose-1-phosphatase precursor K01085; COG: NOG06770 non supervised orthologous group; Psort location: Periplasmic, score:10.00. (413 aa) |
| | acyP | Hypothetical protein; KEGG: stm:STM1083 1.2e-39 yccX; putative phosphohydrolase K01512; COG: COG1254 Acylphosphatases; Psort location: Cytoplasmic, score:8.96. (93 aa) |
| | mgsA | Hypothetical protein; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (152 aa) |
| | serC | Hypothetical protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa) |
| | CKO_02168 | Hypothetical protein; KEGG: stm:STM0973 0. pflB; pyruvate formate lyase I K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score:9.97. (760 aa) |
| | CKO_02211 | Hypothetical protein; KEGG: ecj:JW0854 5.8e-159 ltaE; L-allo-threonine aldolase, PLP-dependent K01620; COG: COG2008 Threonine aldolase. (318 aa) |
| | CKO_02256 | Hypothetical protein; KEGG: stm:STM0874 3.8e-116 mdaA; oxygen-insensitive NADPH nitroreductase; COG: COG0778 Nitroreductase; Belongs to the flavin oxidoreductase frp family. (240 aa) |
| | CKO_02287 | Hypothetical protein; KEGG: ssn:SSO_0805 0. ybiW; putative formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score:9.97. (810 aa) |
| | CKO_02363 | Hypothetical protein; KEGG: ecp:ECP_0784 0. aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score:9.26. (752 aa) |
| | pgl | Hypothetical protein; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (372 aa) |
| | CKO_02379 | Hypothetical protein; Converts alpha-aldose to the beta-anomer. (346 aa) |
| | gpmA | Hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa) |
| | glmS-2 | Hypothetical protein; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (149 aa) |
| | glmE | Hypothetical protein; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (481 aa) |
| | CKO_02419 | Hypothetical protein; KEGG: ece:Z0892 4.3e-211 putative methylaspartate ammonia-lyase K04835; COG: COG3799 Methylaspartate ammonia-lyase; Psort location: Cytoplasmic, score:8.96. (413 aa) |
| | CKO_02424 | Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (550 aa) |
| | sucD | Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa) |
| | sucC | Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | CKO_02433 | Hypothetical protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (406 aa) |
| | CKO_02434 | Hypothetical protein; KEGG: sec:SC0740 0. sucA; 2-oxoglutarate dehydrogenase (decarboxylase component) K00164; COG: COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes; Psort location: Cytoplasmic, score:9.26. (933 aa) |
| | CKO_02435 | Hypothetical protein; KEGG: spt:SPA2008 8.3e-128 sdhB; succinate dehydrogenase iron-sulfur protein K00240; COG: COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (238 aa) |
| | CKO_02436 | Hypothetical protein; KEGG: ssn:SSO_0674 0. sdhA; succinate dehydrogenase, flavoprotein subunit K00239; COG: COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa) |
| | CKO_02437 | Hypothetical protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa) |
| | CKO_02438 | Hypothetical protein; KEGG: ecc:c0798 5.8e-65 sdhC; succinate dehydrogenase cytochrome b-556 subunit K00241; COG: COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; Psort location: CytoplasmicMembrane, score:10.00. (134 aa) |
| | CKO_02439 | Hypothetical protein; KEGG: sec:SC0736 1.7e-225 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.26. (427 aa) |
| | CKO_02471 | Hypothetical protein; KEGG: eco:b0688 8.8e-291 pgm, blu; phosphoglucomutase K01835; COG: COG0033 Phosphoglucomutase. (546 aa) |
| | CKO_02596 | Hypothetical protein; KEGG: stm:STM0578 6.5e-105 nfnB; dihydropteridine reductase/oxygen-insensitive NAD(P)H nitroreductase K00357; COG: COG0778 Nitroreductase. (217 aa) |
| | folD | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa) |
| | CKO_02713 | Hypothetical protein; KEGG: sec:SC0500 8.5e-174 putative cysteine synthase/cystathionine beta-synthase K01738; COG: COG0031 Cysteine synthase; Psort location: Cytoplasmic, score:8.96. (351 aa) |
| | CKO_02807 | Hypothetical protein; KEGG: stm:STM0372 1.2e-165 hemB; delta-aminolevulinic acid dehydratase K01698; COG: COG0113 Delta-aminolevulinic acid dehydratase; Psort location: Cytoplasmic, score:8.96; Belongs to the ALAD family. (324 aa) |
| | ppc | Hypothetical protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (883 aa) |
| | CKO_03043 | Hypothetical protein; KEGG: stm:STM4114 0. pflD; putative pyruvate formate lyase II K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score:9.97. (765 aa) |
| | CKO_03051 | Hypothetical protein; KEGG: stt:t3511 5.6e-154 metF; 5,10 methylenetetrahydrofolate reductase K00297; COG: COG0685 5,10-methylenetetrahydrofolate reductase; Psort location: Cytoplasmic, score:8.96. (296 aa) |
| | CKO_03053 | Hypothetical protein; KEGG: azo:azo3958 9.0e-44 pcaC; 4-carboxymuconolactone decarboxylase K01607; COG: COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; Psort location: Cytoplasmic, score:8.96. (123 aa) |
| | CKO_03054 | Hypothetical protein; KEGG: eco:b3940 0. metL, metM; aspartokinase II and homoserine dehydrogenase II K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. (810 aa) |
| | CKO_03075 | Hypothetical protein; KEGG: ecj:JW3896 1.5e-167 glpX; fructose 1,6-bisphosphatase II K02446; COG: COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins; Psort location: Cytoplasmic, score:8.96. (336 aa) |
| | tpiA | Hypothetical protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa) |
| | pfkA | Hypothetical protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa) |
| | rhaB | Hypothetical protein; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family. (471 aa) |
| | rhaA | Hypothetical protein; KEGG: ecj:JW5561 2.2e-221 rhaA; L-rhamnose isomerase K01813; COG: COG4806 L-rhamnose isomerase; Psort location: Cytoplasmic, score:8.96. (419 aa) |
| | rhaD | Hypothetical protein; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily. (275 aa) |
| | CKO_03104 | Hypothetical protein; KEGG: stm:STM4044 2.5e-190 putative alcohol dehydrogenase K00001; COG: COG1454 Alcohol dehydrogenase, class IV; Psort location: Cytoplasmic, score:9.26. (382 aa) |
| | CKO_03116 | Hypothetical protein; KEGG: ecs:ECs4820 6.0e-102 formate dehydrogenase-O major subunit K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.76. (195 aa) |
| | CKO_03117 | Hypothetical protein; KEGG: sty:STY3839 0. fdoG; formate dehydrogenase-O, major subunit K00123; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Periplasmic, score:9.44; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (804 aa) |
| | CKO_03118 | Hypothetical protein; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa) |
| | CKO_03119 | Hypothetical protein; KEGG: sec:SC3925 4.6e-111 fdoI; formate dehydrogenase, cytochrome b556 (FDO) subunit K00127; COG: COG2864 Cytochrome b subunit of formate dehydrogenase; Psort location: CytoplasmicMembrane, score:10.00. (211 aa) |
| | CKO_03127 | Hypothetical protein; KEGG: lil:LA1476 2.6e-09 putative haloacid dehalogenase-like hydrolase K01560; COG: COG1011 Predicted hydrolase (HAD superfamily); Psort location: Cytoplasmic, score:8.96. (238 aa) |
| | CKO_03140 | Hypothetical protein; KEGG: sdy:SDY_3873 1.3e-250 glnA; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.97. (477 aa) |
| | CKO_03180 | Hypothetical protein; KEGG: eco:b0186 0. ldcC; lysine decarboxylase 2, constitutive K01582; COG: COG1982 Arginine/lysine/ornithine decarboxylases. (712 aa) |
| | accA | Hypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | dapD | Hypothetical protein; KEGG: spt:SPA0219 1.1e-141 dapD; 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase K00674; COG: COG2171 Tetrahydrodipicolinate N-succinyltransferase; Psort location: Cytoplasmic, score:9.97; Belongs to the transferase hexapeptide repeat family. (274 aa) |
| | hemL | Hypothetical protein; KEGG: sbo:SBO_0143 1.2e-183 hemL; glutamate-1-semialdehyde aminotransferase K01845; COG: COG0001 Glutamate-1-semialdehyde aminotransferase; Psort location: Cytoplasmic, score:8.96. (352 aa) |
| | CKO_03252 | Hypothetical protein; KEGG: sec:SC0157 0. acnB; aconitate hydratase 2 K01682; COG: COG1049 Aconitase B; Psort location: Cytoplasmic, score:8.96; Belongs to the aconitase/IPM isomerase family. (874 aa) |
| | CKO_03256 | Hypothetical protein; KEGG: sec:SC0153 5.3e-252 lpdA; lipoamide dehydrogenase (NADH); component of 2-oxodehydrogenase and pyruvate complexes; L protein of glycine cleavage complex second part K00382; COG: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Psort location: Cytoplasmic, score:9.97. (475 aa) |
| | CKO_03258 | Hypothetical protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (630 aa) |
| | CKO_03259 | Hypothetical protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa) |
| | araD | Hypothetical protein; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction). (231 aa) |
| | dapB | Hypothetical protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | tal-2 | Hypothetical protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa) |
| | CKO_03383 | Hypothetical protein; KEGG: sbo:SBO_0003 1.6e-213 thrC; threonine synthase K01733; COG: COG0498 Threonine synthase; Psort location: Cytoplasmic, score:8.96. (428 aa) |
| | thrB | Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) |
| | CKO_03385 | Hypothetical protein; KEGG: sec:SC0002 0. thrA; aspartokinase I K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. (820 aa) |
| | gpmB | Hypothetical protein; KEGG: stm:STM4585 5.6e-106 gpmB; putative phosphoglyceromutase 2 K01834; COG: COG0406 Fructose-2,6-bisphosphatase; Psort location: Cytoplasmic, score:8.96; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa) |
| | CKO_03400 | Hypothetical protein; KEGG: ecc:c5473 2.5e-167 serB; phosphoserine phosphatase K01079; COG: COG0560 Phosphoserine phosphatase. (334 aa) |
| | CKO_03534 | Hypothetical protein; KEGG: eci:UTI89_C4876 3.3e-172 yjgB; putative oxidoreductase K00100; COG: COG1064 Zn-dependent alcohol dehydrogenases. (339 aa) |
| | CKO_03556 | Hypothetical protein; KEGG: sec:SC4320 6.1e-148 arcC; putative carbamate kinase K00926; COG: COG0549 Carbamate kinase; Psort location: Cytoplasmic, score:8.96. (310 aa) |
| | CKO_03575 | Hypothetical protein; KEGG: vvy:VVA1395 5.3e-165 phosphotransferase system, fructose-specific IIC component K02769:K02770; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score:10.00. (465 aa) |
| | fbp | Hypothetical protein; KEGG: ecc:c5329 5.9e-182 fbp; fructose-1,6-bisphosphatase K03841; COG: COG0158 Fructose-1,6-bisphosphatase; Psort location: Cytoplasmic, score:8.96. (393 aa) |
| | cysQ | Hypothetical protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (246 aa) |
| | ulaF | Hypothetical protein; Catalyzes the isomerization of L-ribulose 5-phosphate to D- xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization. (228 aa) |
| | CKO_03638 | Hypothetical protein; KEGG: ecs:ECs5173 1.1e-143 putative hexulose-6-phosphate isomerase K03079; COG: COG3623 Putative L-xylulose-5-phosphate 3-epimerase; Psort location: Cytoplasmic, score:8.96. (284 aa) |
| | CKO_03639 | Hypothetical protein; KEGG: ece:Z5805 4.9e-107 sgaH; putative hexulose-6-phosphate synthase K03078; COG: COG0269 3-hexulose-6-phosphate synthase and related proteins; Psort location: Cytoplasmic, score:8.96. (212 aa) |
| | CKO_03641 | Hypothetical protein; KEGG: ecc:c5284 2.0e-69 ptxA; unknown pentitol phosphotransferase enzyme II, A component K02821; COG: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); Psort location: CytoplasmicMembrane, score:7.88. (155 aa) |
| | CKO_03642 | Hypothetical protein; KEGG: ecs:ECs5170 2.1e-35 unknown pentitol phosphotransferase enzyme II, B component K02822; COG: COG3414 Phosphotransferase system, galactitol-specific IIB component; Psort location: Cytoplasmic, score:8.96. (85 aa) |
| | CKO_03643 | Hypothetical protein; KEGG: ppr:PBPRB0273 1.3e-168 putative SgaT protein K02822:K03475; COG: COG3037 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score:10.00. (465 aa) |
| | ulaG | Hypothetical protein; Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3- keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions; Belongs to the UlaG family. (359 aa) |
| | CKO_03678 | Hypothetical protein; KEGG: sec:SC4222 0. frdA; fumarate reductase, anaerobic, flavoprotein subunit K00244; COG: COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Psort location: Periplasmic, score:9.44. (608 aa) |
| | CKO_03679 | Hypothetical protein; KEGG: stm:STM4342 2.4e-130 frdB; fumarate reductase, anaerobic, Fe-S protein subunit K00245; COG: COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Psort location: Cytoplasmic, score:8.96. (244 aa) |
| | frdC | Hypothetical protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa) |
| | frdD | Hypothetical protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa) |
| | CKO_03720 | Hypothetical protein; KEGG: vvy:VV2243 2.9e-148 adenylosuccinate lyase K01857; COG: COG0015 Adenylosuccinate lyase; Psort location: Cytoplasmic, score:8.96. (456 aa) |
| | CKO_03749 | Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa) |
| | CKO_03782 | Hypothetical protein; KEGG: eco:b4090 3.5e-65 rpiB, yjcA, alsI; ribose 5-phosphate isomerase B K01808; COG: COG0698 Ribose 5-phosphate isomerase RpiB. (151 aa) |
| | CKO_03788 | Hypothetical protein; KEGG: eci:UTI89_C4681 1.3e-113 yjcU; D-allulose-6-phosphate 3-epimerase; COG: COG0036 Pentose-5-phosphate-3-epimerase; Psort location: Cytoplasmic, score:8.96. (222 aa) |
| | alsK | Hypothetical protein; Catalyzes the phosphorylation of D-allose to D-allose 6- phosphate. (304 aa) |
| | CKO_03797 | Hypothetical protein; KEGG: ecs:ECs5069 3.9e-137 putative fructose-bisphosphate aldolase K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score:8.96. (286 aa) |
| | nrfA | Hypothetical protein; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (478 aa) |
| | acs | Hypothetical protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (652 aa) |
| | CKO_03848 | Hypothetical protein; KEGG: ecc:c5039 3.1e-160 putative lactate dehydrogenase K00025; COG: COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family. (357 aa) |
| | sucD-2 | Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | sucC-2 | Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa) |
| | CKO_03852 | Hypothetical protein; KEGG: eci:UTI89_C4633 9.6e-198 subunit of 2-oxoglutarate dehydrogenase K00382; COG: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Psort location: Cytoplasmic, score:9.97. (472 aa) |
| | CKO_03853 | Hypothetical protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (387 aa) |
| | CKO_03854 | Hypothetical protein; KEGG: eci:UTI89_C4630 0. 2-oxoglutarate dehydrogenase E1 component K00164; COG: COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes; Psort location: Cytoplasmic, score:9.26. (914 aa) |
| | pgi | Hypothetical protein; KEGG: stm:STM4221 2.8e-294 pgi; glucosephosphate isomerase K01810; COG: COG0166 Glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score:9.26; Belongs to the GPI family. (549 aa) |
| | CKO_03894 | Hypothetical protein; KEGG: eco:b4024 3.1e-215 lysC, apk; aspartate kinase III K00928; COG: COG0527 Aspartokinases; Belongs to the aspartokinase family. (453 aa) |
| | CKO_03905 | Hypothetical protein; KEGG: ecc:c4972 1.4e-228 aceA; isocitrate lyase K01637; COG: COG2224 Isocitrate lyase; Psort location: Cytoplasmic, score:9.97. (439 aa) |
| | CKO_03906 | Hypothetical protein; KEGG: stm:STM4183 5.2e-277 aceB; malate synthase A K01638; COG: COG2225 Malate synthase; Psort location: Cytoplasmic, score:9.97. (533 aa) |
| | CKO_03984 | Hypothetical protein; COG: COG3718 Uncharacterized enzyme involved in inositol metabolism; Psort location: Cytoplasmic, score:8.96. (271 aa) |
| | CKO_03985 | Hypothetical protein; KEGG: hne:HNE_2184 2.4e-73 iolE; 2-keto-myo-inositol dehydratase K01726; COG: COG1082 Sugar phosphate isomerases/epimerases; Psort location: Cytoplasmic, score:8.96. (296 aa) |
| | CKO_03986 | Hypothetical protein; KEGG: bpm:BURPS1710b_1831 2.4e-192 iolC; IolC protein K03338; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score:9.97. (634 aa) |
| | CKO_03991 | Hypothetical protein; KEGG: yps:YPTB1073 4.5e-152 putative myo-inositol 2-dehydrogenase K00010; COG: COG0673 Predicted dehydrogenases and related proteins. (328 aa) |
| | CKO_03993 | Hypothetical protein; KEGG: ypm:YP_1136 4.9e-297 ilvB1; putative thiamine pyrophosphate-dependent protein K03336; COG: COG3962 Acetolactate synthase; Belongs to the TPP enzyme family. (636 aa) |
| | glaH | Hypothetical protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (325 aa) |
| | lhgD | Hypothetical protein; Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG) to alpha-ketoglutarate and couples to the respiratory chain by feeding electrons from the reaction into the membrane quinone pool. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Reaction=(S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol; Xref=Rhea:RHEA:58664, ChEBI:CHEBI:16782, ChEBI:CHEBI:16810, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:58665; Belongs to the L2HGDH family. (422 aa) |
| | CKO_04008 | Hypothetical protein; KEGG: stm:STM2791 1.7e-239 gabD; succinate-semialdehyde dehydrogenase I K00135; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26. (482 aa) |
| | CKO_04009 | Hypothetical protein; KEGG: ecj:JW2637 1.5e-208 gabT; 4-aminobutyrate aminotransferase, PLP-dependent K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa) |
| | CKO_04096 | Hypothetical protein; COG: NOG14130 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96. (78 aa) |
| | CKO_04097 | Hypothetical protein; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. (475 aa) |
| | CKO_04098 | Hypothetical protein; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase. (197 aa) |
| | cysC | Hypothetical protein; Catalyzes the synthesis of activated sulfate. (201 aa) |
| | cysN | Hypothetical protein; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (475 aa) |
| | cysD | Hypothetical protein; KEGG: ecp:ECP_2734 3.9e-162 sulfate adenylyltransferase subunit 2 K00957; COG: COG0175 3-phosphoadenosine 5-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; Psort location: Cytoplasmic, score:8.96. (302 aa) |
| | cysH | Hypothetical protein; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (244 aa) |
| | cysI | Hypothetical protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (570 aa) |
| | cysJ | Hypothetical protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (601 aa) |
| | eno-2 | Hypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa) |
| | CKO_04140 | Hypothetical protein; KEGG: stt:t2868 5.4e-172 glycerate kinase K00865; COG: COG1929 Glycerate kinase; Psort location: Cytoplasmic, score:8.96; Belongs to the glycerate kinase type-1 family. (380 aa) |
| | CKO_04157 | Hypothetical protein; KEGG: stm:STM2973 2.3e-187 fucO; L-1,2-propanediol oxidoreductase K00048; COG: COG1454 Alcohol dehydrogenase, class IV; Psort location: Cytoplasmic, score:9.26. (382 aa) |
| | fucA | Hypothetical protein; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. (215 aa) |
| | fucI | Hypothetical protein; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (591 aa) |
| | fucK | Hypothetical protein; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family. (472 aa) |
| | lysA | Hypothetical protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) |
| | CKO_04222 | Hypothetical protein; KEGG: eci:UTI89_C3247 5.2e-190 yqeF; probable acetyl-CoA acetyltransferase K00626; COG: COG0183 Acetyl-CoA acetyltransferase; Psort location: Cytoplasmic, score:9.97; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | CKO_04278 | Hypothetical protein; KEGG: eco:b2913 5.8e-207 serA; D-3-phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score:9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa) |
| | rpiA | Hypothetical protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa) |
| | CKO_04293 | Hypothetical protein; KEGG: ssn:SSO_0497 1.3e-92 arcC; putative carbamate kinase K00926; COG: COG0549 Carbamate kinase; Belongs to the carbamate kinase family. (301 aa) |
| | CKO_04295 | Hypothetical protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | pgk | Hypothetical protein; KEGG: ecc:c3504 4.2e-197 pgk; phosphoglycerate kinase K00927; COG: COG0126 3-phosphoglycerate kinase; Psort location: Cytoplasmic, score:9.26. (404 aa) |
| | CKO_04304 | Hypothetical protein; COG: COG3722 Transcriptional regulator. (169 aa) |
| | CKO_04305 | KEGG: ypn:YPN_3759 7.8e-93 hypothetical protein K02446; COG: COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins. (323 aa) |
| | CKO_04309 | Hypothetical protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (673 aa) |
| | CKO_04377 | Hypothetical protein; KEGG: pfl:PFL_2420 1.3e-131 D-isomer specific 2-hydroxyacid dehydrogenase family protein K00002; COG: COG1064 Zn-dependent alcohol dehydrogenases; Psort location: Cytoplasmic, score:8.96. (351 aa) |
| | CKO_04388 | Hypothetical protein; KEGG: ecc:c3731 1.3e-298 hybC; hydrogenase-2 large chain precursor K06281; COG: COG0374 Ni,Fe-hydrogenase I large subunit; Psort location: Periplasmic, score:9.44; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa) |
| | CKO_04391 | Hypothetical protein; KEGG: sty:STY3321 1.0e-202 hyb0; hydrogenase small chain K06282; COG: COG1740 Ni,Fe-hydrogenase I small subunit; Psort location: Periplasmic, score:9.76. (372 aa) |
| | CKO_04395 | Hypothetical protein; KEGG: eci:UTI89_C3421 1.5e-153 putative enzyme K01061; COG: COG0412 Dienelactone hydrolase and related enzymes. (318 aa) |
| | ureA | Hypothetical protein; KEGG: ece:Z1143 6.1e-45 ureA; putative urease structural subunit A (gamma) K01430; COG: COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. (100 aa) |
| | ureB | Hypothetical protein; KEGG: ece:Z1144 5.9e-40 ureB; putative urease structural subunit B (beta) K01429; COG: COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family. (106 aa) |
| | ureC | Hypothetical protein; KEGG: ece:Z1584 1.5e-279 ureC_2; putative urease structural subunit C (alpha) K01428; COG: COG0804 Urea amidohydrolase (urease) alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (567 aa) |
| | CKO_04479 | Hypothetical protein; KEGG: rle:RL2900 2.7e-129 dhaK; putative dihydroxyacetone kinase K00863; COG: COG2376 Dihydroxyacetone kinase. (552 aa) |
| | patA | Hypothetical protein; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (503 aa) |
| | CKO_04514 | Hypothetical protein; KEGG: stm:STM3241 0. tdcE; pyruvate formate-lyase 4/2-ketobutyrate formate-lyase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score:9.97. (764 aa) |
| | CKO_04521 | Hypothetical protein; KEGG: sfx:S3376 1.1e-171 yhaD; glycerate kinase K00865; COG: COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. (381 aa) |
| | CKO_04620 | Hypothetical protein; KEGG: sbo:SBO_3170 0. gltB; glutamate synthase, large subunit K00265; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score:8.96. (1498 aa) |
| | CKO_04622 | Hypothetical protein; KEGG: sty:STY3511 2.6e-250 gltD; glutamate synthase (NADPH) small chain K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score:9.97. (472 aa) |
| | mdh | Hypothetical protein; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa) |
| | CKO_04646 | Hypothetical protein; KEGG: eca:ECA0280 2.4e-201 succinate-semialdehyde dehydrogenase [NADP+] K00135; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26. (482 aa) |
| | CKO_04666 | Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa) |
| | CKO_04667 | Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | CKO_04773 | Hypothetical protein; KEGG: spt:SPA3330 1.9e-153 prkB; phosphoribulokinase K00855; COG: COG3954 Phosphoribulokinase. (289 aa) |
| | argD | Hypothetical protein; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa) |
| | CKO_04789 | Hypothetical protein; KEGG: stm:STM3474 0. nirB; nitrite reductase, large subunit K00362; COG: COG1251 NAD(P)H-nitrite reductase; Psort location: Cytoplasmic, score:9.97; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (847 aa) |
| | CKO_04790 | Hypothetical protein; KEGG: sfl:SF3385 3.8e-52 nirD; nitrite reductase (NAD(P)H) subunit K00363; COG: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Psort location: Cytoplasmic, score:9.97. (108 aa) |
| | cysG | Hypothetical protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (457 aa) |
| | CKO_04807 | Hypothetical protein; KEGG: eci:UTI89_C3884 2.7e-113 rpe; D-ribulose-5-phosphate 3-epimerase K01783; COG: COG0036 Pentose-5-phosphate-3-epimerase; Psort location: Cytoplasmic, score:8.96; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa) |
| | pckA | Hypothetical protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa) |
| | glpE | Hypothetical protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (108 aa) |
| | asd | Hypothetical protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (368 aa) |
| | CKO_04856 | Hypothetical protein; KEGG: spt:SPA3393 1.7e-79 gntK; putative gluconokinase K00851; COG: COG3265 Gluconate kinase. (163 aa) |
| | CKO_04884 | Hypothetical protein; KEGG: eca:ECA2053 6.6e-167 gabT, goaG; 4-aminobutyrate aminotransferase K00823:K07250; COG: COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Psort location: Cytoplasmic, score:8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa) |
| | CKO_04968 | Hypothetical protein; KEGG: stm:STM3612 6.6e-151 kdgK; ketodeoxygluconokinase K00874; COG: COG0524 Sugar kinases, ribokinase family. (309 aa) |
| | CKO_05007 | Hypothetical protein; KEGG: bur:Bcep18194_A5029 1.3e-104 sugar kinase, ribokinase family K00874; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score:9.97. (312 aa) |
| | ghrB | Hypothetical protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. (324 aa) |
| | CKO_05039 | Hypothetical protein; KEGG: stm:STM3675 1.1e-107 sgbH; putative 3-hexulose-6-phosphate isomerase K03081; COG: COG0269 3-hexulose-6-phosphate synthase and related proteins; Psort location: Cytoplasmic, score:8.96. (220 aa) |
| | CKO_05040 | Hypothetical protein; KEGG: ecp:ECP_3687 5.0e-146 putative hexulose-6-phosphate isomerase K03082; COG: COG3623 Putative L-xylulose-5-phosphate 3-epimerase. (286 aa) |
| | CKO_05041 | Hypothetical protein; KEGG: sty:STY4119 2.5e-119 yiaS, sgbE; putative sugar isomerase K03080; COG: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases. (231 aa) |
| | CKO_05043 | Hypothetical protein; KEGG: stm:STM3680 5.6e-273 aldB; aldehyde dehydrogenase B K00138; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26. (512 aa) |
| | CKO_05045 | Hypothetical protein; KEGG: ecc:c4410 1.9e-183 yiaY; probable alcohol dehydrogenase K00001; COG: COG1454 Alcohol dehydrogenase, class IV; Psort location: Cytoplasmic, score:9.26. (422 aa) |
| | CKO_05064 | Hypothetical protein; KEGG: sdy:SDY_4040 2.0e-142 cysE; serine acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score:9.26; Belongs to the transferase hexapeptide repeat family. (273 aa) |
| | gpmI | Hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (507 aa) |
| | CKO_05127 | Hypothetical protein; COG: NOG14137 non supervised orthologous group. (247 aa) |
| | CKO_05128 | Hypothetical protein; KEGG: stm:STM3768 1.6e-170 putative selenocysteine synthase [L-seryl-tRNA(Ser) selenium transferase K01042; COG: COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; Psort location: Cytoplasmic, score:8.96. (369 aa) |
| | CKO_05129 | Hypothetical protein; KEGG: lsl:LSL_1949 6.6e-48 PTS system, mannose-specific IID component K00890; COG: COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; Psort location: CytoplasmicMembrane, score:10.00. (286 aa) |
| | CKO_05130 | Hypothetical protein; KEGG: lsl:LSL_1950 2.3e-29 PTS system, mannose-specific IIC component K00890; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: CytoplasmicMembrane, score:10.00. (249 aa) |
| | CKO_05131 | Hypothetical protein; KEGG: spt:SPA3621 8.7e-78 putative PTS system protein K02794; COG: COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; Psort location: Cytoplasmic, score:9.26. (161 aa) |
| | CKO_05132 | Hypothetical protein; KEGG: sec:SC3692 1.0e-60 putative phosphotransferase system enzyme IIA K02793; COG: COG2893 Phosphotransferase system, mannose/fructose-specific component IIA. (135 aa) |
