(32 nodes) Arginine and proline metabolism network (Jannaschia sp. CCS1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Jann_0016	Glycine amidinotransferase. (369 aa)
	Jann_0028	Aromatic amino acid aminotransferase apoenzyme. (399 aa)
	Jann_0277	Agmatinase; Belongs to the arginase family. (322 aa)
	Jann_0299	Prolyl aminopeptidase. Serine peptidase. MEROPS family S33; Belongs to the peptidase S33 family. (316 aa)
	Jann_0363	Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase. (285 aa)
	Jann_0776	Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (481 aa)
	Jann_0786	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (779 aa)
	Jann_0801	Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (389 aa)
	speE	Spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (567 aa)
	Jann_1124	Gamma-glutamylputrescine oxidase. (453 aa)
	Jann_1304	Amidase; Belongs to the amidase family. (437 aa)
	Jann_1306	N-isopropylammelide isopropylaminohydrolase. (431 aa)
	Jann_1474	Amidohydrolase 3. (458 aa)
	Jann_1478	Creatininase. (261 aa)
	Jann_1529	Proline racemase; Belongs to the proline racemase family. (346 aa)
	Jann_1530	Ornithine cyclodeaminase. (314 aa)
	Jann_1956	Aminotransferase. (398 aa)
	proB	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (368 aa)
	proA	Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (422 aa)
	Jann_2340	Agmatinase; Belongs to the arginase family. (321 aa)
	speH	S-adenosylmethionine decarboxylase related protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (161 aa)
	Jann_2532	Amidase. (463 aa)
	Jann_2612	Peptidase M24. (386 aa)
	Jann_2654	Aminotransferase. (400 aa)
	proC	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa)
	Jann_3494	L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1135 aa)
	Jann_3507	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa)
	Jann_3764	5-oxoprolinase (ATP-hydrolyzing). (564 aa)
	Jann_3765	5-oxoprolinase (ATP-hydrolyzing). (690 aa)
	Jann_3811	5-oxoprolinase (ATP-hydrolyzing). (693 aa)
	Jann_3812	5-oxoprolinase (ATP-hydrolyzing). (568 aa)
	Jann_4025	Aldehyde dehydrogenase. (477 aa)

Your Current Organism:

Jannaschia sp. CCS1

NCBI taxonomy Id: 290400
Other names: J. sp. CCS1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Jann_0016	Jann_0776	Jann_0016	Jann_0776	Glycine amidinotransferase.	Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.900
Jann_0016	Jann_0786	Jann_0016	Jann_0786	Glycine amidinotransferase.	Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.	0.900
Jann_0016	Jann_1304	Jann_0016	Jann_1304	Glycine amidinotransferase.	Amidase; Belongs to the amidase family.	0.900
Jann_0016	Jann_1478	Jann_0016	Jann_1478	Glycine amidinotransferase.	Creatininase.	0.900
Jann_0016	Jann_1956	Jann_0016	Jann_1956	Glycine amidinotransferase.	Aminotransferase.	0.901
Jann_0016	Jann_2532	Jann_0016	Jann_2532	Glycine amidinotransferase.	Amidase.	0.900
Jann_0016	Jann_3494	Jann_0016	Jann_3494	Glycine amidinotransferase.	L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.800
Jann_0016	Jann_4025	Jann_0016	Jann_4025	Glycine amidinotransferase.	Aldehyde dehydrogenase.	0.900
Jann_0028	Jann_0363	Jann_0028	Jann_0363	Aromatic amino acid aminotransferase apoenzyme.	Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase.	0.907
Jann_0028	Jann_2654	Jann_0028	Jann_2654	Aromatic amino acid aminotransferase apoenzyme.	Aminotransferase.	0.917
Jann_0028	Jann_3494	Jann_0028	Jann_3494	Aromatic amino acid aminotransferase apoenzyme.	L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.910
Jann_0277	Jann_0801	Jann_0277	Jann_0801	Agmatinase; Belongs to the arginase family.	Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.916
Jann_0277	Jann_2340	Jann_0277	Jann_2340	Agmatinase; Belongs to the arginase family.	Agmatinase; Belongs to the arginase family.	0.921
Jann_0277	Jann_3494	Jann_0277	Jann_3494	Agmatinase; Belongs to the arginase family.	L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.542
Jann_0277	speE	Jann_0277	Jann_0855	Agmatinase; Belongs to the arginase family.	Spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	0.900
Jann_0299	Jann_1530	Jann_0299	Jann_1530	Prolyl aminopeptidase. Serine peptidase. MEROPS family S33; Belongs to the peptidase S33 family.	Ornithine cyclodeaminase.	0.900
Jann_0299	Jann_3494	Jann_0299	Jann_3494	Prolyl aminopeptidase. Serine peptidase. MEROPS family S33; Belongs to the peptidase S33 family.	L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.900
Jann_0299	proC	Jann_0299	Jann_3328	Prolyl aminopeptidase. Serine peptidase. MEROPS family S33; Belongs to the peptidase S33 family.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.901
Jann_0363	Jann_0028	Jann_0363	Jann_0028	Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase.	Aromatic amino acid aminotransferase apoenzyme.	0.907
Jann_0363	Jann_2654	Jann_0363	Jann_2654	Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase.	Aminotransferase.	0.911