(45 nodes) Butanoate metabolism network (Jannaschia sp. CCS1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Jann_0137	Thiamine pyrophosphate enzyme-like TPP-binding protein; Belongs to the TPP enzyme family. (538 aa)
	Jann_0262	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	Jann_0492	Acetoacetyl-CoA reductase. (240 aa)
	Jann_0493	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	Jann_0543	3-hydroxyacyl-CoA dehydrogenase. (292 aa)
	Jann_0650	3-oxoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	Jann_0668	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	Jann_0676	3-hydroxyacyl-CoA dehydrogenase. (687 aa)
	Jann_0804	Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (264 aa)
	Jann_0809	Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (606 aa)
	Jann_0810	Succinate dehydrogenase subunit D. (123 aa)
	Jann_0811	Succinate dehydrogenase subunit C. (127 aa)
	Jann_1005	butyryl-CoA:acetate CoA transferase. (207 aa)
	Jann_1009	3-oxoacid CoA-transferase subunit A. (231 aa)
	Jann_1116	Polyhydroxyalkanoate depolymerase intracellular. (433 aa)
	Jann_1117	Poly(R)-hydroxyalkanoic acid synthase class I. (612 aa)
	Jann_1121	Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
	Jann_1149	hydroxymethylglutaryl-CoA lyase. (284 aa)
	Jann_1324	Short-chain dehydrogenase/reductase SDR. (244 aa)
	Jann_1406	Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. (563 aa)
	Jann_1830	Asp/Glu racemase. (246 aa)
	Jann_1893	Acetolactate synthase, small subunit. (185 aa)
	Jann_1897	Acetolactate synthase, large subunit. (588 aa)
	Jann_1908	Enoyl-CoA hydratase/isomerase. (346 aa)
	Jann_2311	3-hydroxybutyrate dehydrogenase. (261 aa)
	Jann_2615	Short-chain dehydrogenase/reductase SDR. (257 aa)
	Jann_2975	Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
	Jann_2977	3-hydroxyacyl-CoA dehydrogenase. (733 aa)
	Jann_3070	4-aminobutyrate aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (433 aa)
	Jann_3072	Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase. (495 aa)
	Jann_3204	Thiamine pyrophosphate enzyme-like TPP-binding protein; Belongs to the TPP enzyme family. (537 aa)
	Jann_3283	Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa)
	Jann_3364	MaoC-like dehydratase. (147 aa)
	Jann_3768	Fumarate reductase/succinate dehydrogenase flavoprotein-like protein. (460 aa)
	Jann_3773	Asp/Glu racemase. (258 aa)
	Jann_3783	hydroxymethylglutaryl-CoA lyase. (319 aa)
	Jann_3820	Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. (522 aa)
	Jann_3829	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (482 aa)
	Jann_3966	Succinate dehydrogenase subunit B. (237 aa)
	Jann_3967	Hypothetical protein. (113 aa)
	Jann_3968	Succinate dehydrogenase subunit C. (114 aa)
	Jann_3969	L-aspartate oxidase. (585 aa)
	Jann_4050	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
	Jann_4110	Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (229 aa)
	Jann_4211	Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)

Your Current Organism:

Jannaschia sp. CCS1

NCBI taxonomy Id: 290400
Other names: J. sp. CCS1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
Jann_0137	Jann_1893	Thiamine pyrophosphate enzyme-like TPP-binding protein; Belongs to the TPP enzyme family.	Acetolactate synthase, small subunit.	0.857
Jann_0137	Jann_3783	Thiamine pyrophosphate enzyme-like TPP-binding protein; Belongs to the TPP enzyme family.	hydroxymethylglutaryl-CoA lyase.	0.423
Jann_0262	Jann_0492	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetoacetyl-CoA reductase.	0.910
Jann_0262	Jann_0493	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.628
Jann_0262	Jann_0543	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyacyl-CoA dehydrogenase.	0.970
Jann_0262	Jann_0650	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-oxoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.632
Jann_0262	Jann_0668	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.716
Jann_0262	Jann_0676	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyacyl-CoA dehydrogenase.	0.997
Jann_0262	Jann_1005	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	butyryl-CoA:acetate CoA transferase.	0.927
Jann_0262	Jann_1009	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-oxoacid CoA-transferase subunit A.	0.921
Jann_0262	Jann_1149	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	hydroxymethylglutaryl-CoA lyase.	0.922
Jann_0262	Jann_1908	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase/isomerase.	0.553
Jann_0262	Jann_2975	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.678
Jann_0262	Jann_2977	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyacyl-CoA dehydrogenase.	0.997
Jann_0262	Jann_3768	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Fumarate reductase/succinate dehydrogenase flavoprotein-like protein.	0.681
Jann_0262	Jann_3783	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	hydroxymethylglutaryl-CoA lyase.	0.922
Jann_0262	Jann_3966	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Succinate dehydrogenase subunit B.	0.711
Jann_0262	Jann_3967	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Hypothetical protein.	0.643
Jann_0262	Jann_3968	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Succinate dehydrogenase subunit C.	0.692
Jann_0262	Jann_3969	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	L-aspartate oxidase.	0.607