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H2BC11 H2BC11 LOC103678852 LOC103678852 LOC103665080-2 LOC103665080-2 LOC103678853 LOC103678853 ENSUMAP00000000727 ENSUMAP00000000727 LOC103665081 LOC103665081 LOC103665080 LOC103665080 ENSUMAP00000001034 ENSUMAP00000001034 LOC103665068 LOC103665068 ENSUMAP00000001139 ENSUMAP00000001139 ENSUMAP00000001147 ENSUMAP00000001147 LOC103665083 LOC103665083 LOC103665205 LOC103665205 LOC103665065 LOC103665065 LOC103665064 LOC103665064 LOC103665063-2 LOC103665063-2 LOC103665063 LOC103665063 LOC103665102 LOC103665102 LOC103665053 LOC103665053 KMT2A KMT2A ENSUMAP00000002159 ENSUMAP00000002159 SETD3 SETD3 POGZ POGZ LOC103665083-2 LOC103665083-2 H2AJ H2AJ CXXC1 CXXC1 GLYR1 GLYR1 RBBP5 RBBP5 H2AC21 H2AC21 H2AC20 H2AC20 H2BC21 H2BC21 LOC103667576 LOC103667576 LOC103665041 LOC103665041 LOC103667570 LOC103667570 LOC103665083-3 LOC103665083-3 H2BC18 H2BC18 KMT5A KMT5A SETD2 SETD2 ASF1B ASF1B H2AZ1 H2AZ1 NCOA6 NCOA6 SETD1B SETD1B WHSC1 WHSC1 ENSUMAP00000008398 ENSUMAP00000008398 ENSUMAP00000008606 ENSUMAP00000008606 KMT2D KMT2D LOC103663868 LOC103663868 MEN1 MEN1 MACROH2A2 MACROH2A2 SMYD1 SMYD1 RBBP7 RBBP7 ENSUMAP00000011850 ENSUMAP00000011850 ASH2L ASH2L SMYD4 SMYD4 H3F3B H3F3B PAGR1 PAGR1 HDAC4 HDAC4 ENSUMAP00000016891 ENSUMAP00000016891 HDAC5 HDAC5 KMT5B KMT5B SETD1A SETD1A HAT1 HAT1 H3F3A H3F3A HDAC11 HDAC11 KMT2C KMT2C ENSUMAP00000021995 ENSUMAP00000021995 H2BE1 H2BE1 LOC103659278 LOC103659278 MACROH2A1 MACROH2A1 HYPM HYPM PSIP1 PSIP1 SMYD2 SMYD2 KAT2B KAT2B HDAC10 HDAC10 DPY30 DPY30 KMT2B KMT2B LOC103665034 LOC103665034 ENSUMAP00000028685 ENSUMAP00000028685 ENSUMAP00000028688 ENSUMAP00000028688 LOC103665044 LOC103665044 LOC103665042 LOC103665042 LOC103665043 LOC103665043 H2BC3 H2BC3 ENSUMAP00000028734 ENSUMAP00000028734 ENSUMAP00000028742 ENSUMAP00000028742 KDM6A KDM6A LOC103665050 LOC103665050 LOC103665047 LOC103665047 H2AC6 H2AC6 H2BC5 H2BC5 LOC103665055 LOC103665055 LOC103665054 LOC103665054 ENSUMAP00000028844 ENSUMAP00000028844 ENSUMAP00000028845 ENSUMAP00000028845 ENSUMAP00000028855 ENSUMAP00000028855 LOC103665194 LOC103665194 ENSUMAP00000028862 ENSUMAP00000028862 LOC103665053-2 LOC103665053-2 ENSUMAP00000028876 ENSUMAP00000028876 LOC103665083-4 LOC103665083-4 LOC103665059 LOC103665059 ENSUMAP00000028897 ENSUMAP00000028897 LOC103665058 LOC103665058 LOC103665083-5 LOC103665083-5 ENSUMAP00000028926 ENSUMAP00000028926 LOC103665060 LOC103665060 LOC103665100 LOC103665100 ENSUMAP00000028939 ENSUMAP00000028939 ENSUMAP00000028953 ENSUMAP00000028953 LOC103665098 LOC103665098 LOC103665083-6 LOC103665083-6 LOC103680203 LOC103680203 MYSM1 MYSM1 DIDO1 DIDO1 SMYD5 SMYD5 WDR5 WDR5 NASP NASP NSD1 NSD1 ENSUMAP00000033775 ENSUMAP00000033775 CARM1 CARM1 WDR5B WDR5B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2BC11Histone H2B; Belongs to the histone H2B family. (153 aa)
LOC103678852Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103665080-2Histone H2A; Belongs to the histone H2A family. (134 aa)
LOC103678853Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUMAP00000000727annotation not available (93 aa)
LOC103665081Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103665080Histone H2A type 1-E-like. (131 aa)
ENSUMAP00000001034annotation not available (132 aa)
LOC103665068Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUMAP00000001139annotation not available (87 aa)
ENSUMAP00000001147annotation not available (149 aa)
LOC103665083Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC103665205Histone H2A type 1-H-like. (132 aa)
LOC103665065Histone H2B; Belongs to the histone H2B family. (125 aa)
LOC103665064Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103665063-2Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
LOC103665063Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC103665102Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103665053Histone H2B; Belongs to the histone H2B family. (126 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (323 aa)
ENSUMAP00000002159annotation not available (370 aa)
SETD3Protein-histidine N-methyltransferase. (604 aa)
POGZPogo transposable element with ZNF domain isoform X1. (1414 aa)
LOC103665083-2Histone H4. (103 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
CXXC1CXXC-type zinc finger protein 1. (684 aa)
GLYR1Putative oxidoreductase GLYR1. (484 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (538 aa)
H2AC21Histone H2A; Belongs to the histone H2A family. (130 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (126 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (141 aa)
LOC103667576Histone H2A; Belongs to the histone H2A family. (144 aa)
LOC103665041Histone H2B; Belongs to the histone H2B family. (132 aa)
LOC103667570Histone H2A type 2-A. (130 aa)
LOC103665083-3Histone H4. (103 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (126 aa)
KMT5AN-lysine methyltransferase SETD8. (327 aa)
SETD2Histone-lysine N-methyltransferase SETD2. (2520 aa)
ASF1BHistone chaperone ASF1B. (202 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
NCOA6Nuclear receptor coactivator 6 isoform X1. (2032 aa)
SETD1BHistone-lysine N-methyltransferase SETD1B. (115 aa)
WHSC1LOW QUALITY PROTEIN: histone-lysine N-methyltransferase NSD2. (629 aa)
ENSUMAP00000008398annotation not available (577 aa)
ENSUMAP00000008606annotation not available (116 aa)
KMT2DLOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2D. (811 aa)
LOC103663868Histone H2B subacrosomal variant-like; Belongs to the histone H2B family. (122 aa)
MEN1Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (422 aa)
MACROH2A2Core histone macro-H2A.2; Belongs to the histone H2A family. (351 aa)
SMYD1Histone-lysine N-methyltransferase SMYD1. (489 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (391 aa)
ENSUMAP00000011850annotation not available (104 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (628 aa)
SMYD4SET and MYND domain-containing protein 4 isoform X1. (832 aa)
H3F3BH3 histone, family 3B. (191 aa)
PAGR1PAXIP1-associated glutamate-rich protein 1. (254 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1142 aa)
ENSUMAP00000016891annotation not available (115 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (679 aa)
KMT5BHistone-lysine N-methyltransferase SUV420H1 isoform X1. (697 aa)
SETD1ALOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1A. (1443 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
H3F3AH3 histone, family 3A. (160 aa)
HDAC11Histone deacetylase 11. (319 aa)
KMT2CHistone-lysine N-methyltransferase 2C. (778 aa)
ENSUMAP00000021995annotation not available (342 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
LOC103659278Histone H2A; Belongs to the histone H2A family. (113 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)
HYPMHuntingtin-interacting protein M. (113 aa)
PSIP1PC4 and SFRS1-interacting protein isoform X1. (530 aa)
SMYD2N-lysine methyltransferase SMYD2. (403 aa)
KAT2BHistone acetyltransferase KAT2B. (826 aa)
HDAC10LOW QUALITY PROTEIN: histone deacetylase 10. (311 aa)
DPY30Protein dpy-30 homolog. (99 aa)
KMT2BHistone-lysine N-methyltransferase 2B. (2526 aa)
LOC103665034Histone H2B; Belongs to the histone H2B family. (127 aa)
ENSUMAP00000028685annotation not available (136 aa)
ENSUMAP00000028688annotation not available (103 aa)
LOC103665044Histone H4. (103 aa)
LOC103665042Histone H2A; Belongs to the histone H2A family. (135 aa)
LOC103665043Histone H3.1-like. (201 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUMAP00000028734annotation not available (139 aa)
ENSUMAP00000028742annotation not available (98 aa)
KDM6ALysine-specific demethylase 6A. (1347 aa)
LOC103665050Histone H4-like. (103 aa)
LOC103665047Histone H2B type 1. (126 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (130 aa)
LOC103665055Histone H2B; Belongs to the histone H2B family. (130 aa)
LOC103665054Histone H4. (103 aa)
ENSUMAP00000028844annotation not available (130 aa)
ENSUMAP00000028845annotation not available (125 aa)
ENSUMAP00000028855annotation not available (142 aa)
LOC103665194Histone H2B type 1-N-like; Belongs to the histone H2B family. (110 aa)
ENSUMAP00000028862annotation not available (96 aa)
LOC103665053-2Histone H2B type 1. (126 aa)
ENSUMAP00000028876annotation not available (92 aa)
LOC103665083-4Histone H4. (103 aa)
LOC103665059Histone H2B type 2-E-like; Belongs to the histone H2B family. (126 aa)
ENSUMAP00000028897annotation not available (93 aa)
LOC103665058Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103665083-5Histone H4. (103 aa)
ENSUMAP00000028926annotation not available (100 aa)
LOC103665060Histone H3; Belongs to the histone H3 family. (136 aa)
LOC103665100Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUMAP00000028939annotation not available (103 aa)
ENSUMAP00000028953annotation not available (139 aa)
LOC103665098Histone H2B type 1. (136 aa)
LOC103665083-6Histone H4. (103 aa)
LOC103680203LOW QUALITY PROTEIN: lysine-specific demethylase 6A-like. (1394 aa)
MYSM1Histone H2A deubiquitinase MYSM1 isoform X1. (812 aa)
DIDO1Death-inducer obliterator 1. (2054 aa)
SMYD5SET and MYND domain-containing protein 5. (385 aa)
WDR5COMPASS component SWD3. (347 aa)
NASPNuclear autoantigenic sperm protein isoform X1. (450 aa)
NSD1Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific isoform X2. (1459 aa)
ENSUMAP00000033775annotation not available (570 aa)
CARM1Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (530 aa)
WDR5BWD repeat-containing protein 5B. (330 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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