(35 nodes) Histone deacetylase complex, and RBB1NT (NUC162) domain network (Ursus maritimus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	SINHCAF	SIN3-HDAC complex associated factor. (221 aa)
	SAP30L	Histone deacetylase complex subunit SAP30L. (169 aa)
	MBD2	methyl-CpG-binding domain protein 2. (285 aa)
	SIN3A	SIN3 transcription regulator family member A. (1274 aa)
	CDK2AP1	Cyclin-dependent kinase 2-associated protein 1. (136 aa)
	MBD3	methyl-CpG-binding domain protein 3 isoform X2. (315 aa)
	GATAD2A	GATA zinc finger domain containing 2A. (639 aa)
	CHD4	LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 4. (1917 aa)
	ARID4B	AT-rich interactive domain-containing protein 4B. (1290 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (498 aa)
	BRMS1L	Breast cancer metastasis-suppressor 1-like protein isoform X2. (323 aa)
	SUDS3	Sin3 histone deacetylase corepressor complex component SDS3. (306 aa)
	WDR73	WD repeat-containing protein 73. (383 aa)
	BRMS1	Breast cancer metastasis-suppressor 1. (348 aa)
	PHF12-2	PHD finger protein 12. (125 aa)
	PHF12	PHD finger protein 12. (257 aa)
	SIN3B	Paired amphipathic helix protein Sin3b. (880 aa)
	LOC103681877	Putative methyl-CpG-binding domain protein 3-like 5. (197 aa)
	CDK2AP2	Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family. (127 aa)
	MTA3	Metastasis associated 1 family member 3. (537 aa)
	MTA2	Metastasis-associated protein MTA2. (689 aa)
	KDM5A	Lysine-specific demethylase 5A. (1694 aa)
	MBD3L1	methyl-CpG-binding domain protein 3-like 1. (199 aa)
	ARID4A	AT-rich interactive domain-containing protein 4A isoform X3. (1286 aa)
	GATAD1	GATA zinc finger domain-containing protein 1. (54 aa)
	PHF21B	PHD finger protein 21B. (305 aa)
	GATAD2B	GATA zinc finger domain containing 2B. (608 aa)
	ING2	Inhibitor of growth protein. (174 aa)
	SAP30	Histone deacetylase complex subunit SAP30. (127 aa)
	LOC103657619	Inhibitor of growth protein. (185 aa)
	NYNRIN	LOW QUALITY PROTEIN: protein NYNRIN. (1785 aa)
	CHD5	chromodomain-helicase-DNA-binding protein 5. (1844 aa)
	ENSUMAP00000034139	annotation not available (300 aa)
	ENSUMAP00000034142	annotation not available (124 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (458 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID4A	ARID4B	ENSUMAP00000023009	ENSUMAP00000009417	AT-rich interactive domain-containing protein 4A isoform X3.	AT-rich interactive domain-containing protein 4B.	0.871
ARID4A	BRMS1	ENSUMAP00000023009	ENSUMAP00000015248	AT-rich interactive domain-containing protein 4A isoform X3.	Breast cancer metastasis-suppressor 1.	0.930
ARID4A	BRMS1L	ENSUMAP00000023009	ENSUMAP00000011308	AT-rich interactive domain-containing protein 4A isoform X3.	Breast cancer metastasis-suppressor 1-like protein isoform X2.	0.931
ARID4A	CHD4	ENSUMAP00000023009	ENSUMAP00000008493	AT-rich interactive domain-containing protein 4A isoform X3.	LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 4.	0.692
ARID4A	CHD5	ENSUMAP00000023009	ENSUMAP00000033546	AT-rich interactive domain-containing protein 4A isoform X3.	chromodomain-helicase-DNA-binding protein 5.	0.674
ARID4A	ENSUMAP00000034139	ENSUMAP00000023009	ENSUMAP00000034139	AT-rich interactive domain-containing protein 4A isoform X3.	annotation not available	0.579
ARID4A	ENSUMAP00000034142	ENSUMAP00000023009	ENSUMAP00000034142	AT-rich interactive domain-containing protein 4A isoform X3.	annotation not available	0.552
ARID4A	GATAD1	ENSUMAP00000023009	ENSUMAP00000026127	AT-rich interactive domain-containing protein 4A isoform X3.	GATA zinc finger domain-containing protein 1.	0.511
ARID4A	GATAD2A	ENSUMAP00000023009	ENSUMAP00000008077	AT-rich interactive domain-containing protein 4A isoform X3.	GATA zinc finger domain containing 2A.	0.634
ARID4A	GATAD2B	ENSUMAP00000023009	ENSUMAP00000028055	AT-rich interactive domain-containing protein 4A isoform X3.	GATA zinc finger domain containing 2B.	0.642
ARID4A	HDAC1	ENSUMAP00000023009	ENSUMAP00000011136	AT-rich interactive domain-containing protein 4A isoform X3.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.925
ARID4A	HDAC2	ENSUMAP00000023009	ENSUMAP00000035417	AT-rich interactive domain-containing protein 4A isoform X3.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.925
ARID4A	ING2	ENSUMAP00000023009	ENSUMAP00000029394	AT-rich interactive domain-containing protein 4A isoform X3.	Inhibitor of growth protein.	0.686
ARID4A	LOC103657619	ENSUMAP00000023009	ENSUMAP00000030649	AT-rich interactive domain-containing protein 4A isoform X3.	Inhibitor of growth protein.	0.739
ARID4A	LOC103681877	ENSUMAP00000023009	ENSUMAP00000017443	AT-rich interactive domain-containing protein 4A isoform X3.	Putative methyl-CpG-binding domain protein 3-like 5.	0.570
ARID4A	MBD2	ENSUMAP00000023009	ENSUMAP00000004231	AT-rich interactive domain-containing protein 4A isoform X3.	methyl-CpG-binding domain protein 2.	0.570
ARID4A	MBD3	ENSUMAP00000023009	ENSUMAP00000007660	AT-rich interactive domain-containing protein 4A isoform X3.	methyl-CpG-binding domain protein 3 isoform X2.	0.570
ARID4A	MBD3L1	ENSUMAP00000023009	ENSUMAP00000019330	AT-rich interactive domain-containing protein 4A isoform X3.	methyl-CpG-binding domain protein 3-like 1.	0.570
ARID4A	MTA2	ENSUMAP00000023009	ENSUMAP00000019237	AT-rich interactive domain-containing protein 4A isoform X3.	Metastasis-associated protein MTA2.	0.558
ARID4A	MTA3	ENSUMAP00000023009	ENSUMAP00000017818	AT-rich interactive domain-containing protein 4A isoform X3.	Metastasis associated 1 family member 3.	0.558