93 items (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EBF1	EBF transcription factor 1. (413 aa)
	ID1	DNA-binding protein inhibitor ID-1. (284 aa)
	LMO4	LIM domain transcription factor LMO4. (165 aa)
	ENSUMAP00000002583	annotation not available (205 aa)
	NEUROD6	Neurogenic differentiation factor. (337 aa)
	LMO3	LIM domain only protein 3. (156 aa)
	SOX5	Transcription factor SOX-5. (397 aa)
	ENSUMAP00000003766	annotation not available (297 aa)
	LDB2	LIM domain-binding protein 2 isoform X1. (373 aa)
	SSBP2	Single-stranded DNA-binding protein 2 isoform X4. (390 aa)
	TCF4	Transcription factor 4 isoform X5. (511 aa)
	ENSUMAP00000004364	annotation not available (196 aa)
	ID2	DNA-binding protein inhibitor ID-2. (134 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
	MYF6	LOW QUALITY PROTEIN: myogenic factor 6. (225 aa)
	MYT1L	Myelin transcription factor 1-like protein. (1191 aa)
	TSHZ1	LOW QUALITY PROTEIN: teashirt homolog 1. (1052 aa)
	CITED1	Cbp/p300-interacting transactivator 1. (201 aa)
	MEF2C	Myocyte-specific enhancer factor 2C isoform X3. (433 aa)
	SALL1	LOW QUALITY PROTEIN: sal-like protein 1. (144 aa)
	MYOG	Myogenin. (208 aa)
	FOXG1	Forkhead box protein G1. (221 aa)
	ISL1	Insulin gene enhancer protein ISL-1. (349 aa)
	TCF3	Transcription factor E2-alpha. (504 aa)
	LYL1	LYL1 basic helix-loop-helix family member. (390 aa)
	LHX8	LIM/homeobox protein Lhx8 isoform X2. (346 aa)
	MEF2B	Myocyte-specific enhancer factor 2B isoform X2. (376 aa)
	FOXP2-2	Forkhead box protein P2. (69 aa)
	HOPX	Homeodomain-only protein. (75 aa)
	PAX8	Paired box protein Pax-8. (459 aa)
	ENSUMAP00000012018	annotation not available (184 aa)
	FGF13	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (226 aa)
	EYA3	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (573 aa)
	SHOX2	Short stature homeobox protein 2. (175 aa)
	FOXP4	Forkhead box protein P4. (608 aa)
	CUX1	Homeobox protein cut-like. (1357 aa)
	ZIC1	Zinc finger protein ZIC 1. (410 aa)
	SIX2	LOW QUALITY PROTEIN: homeobox protein SIX2. (267 aa)
	RUNX3	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (143 aa)
	ID3	Inhibitor of DNA binding 3, HLH protein. (119 aa)
	ALX3	Homeobox protein aristaless-like 3. (371 aa)
	ENSUMAP00000018722	annotation not available (372 aa)
	SIX1	Homeobox protein SIX1. (284 aa)
	SIX6	Homeobox protein SIX6. (246 aa)
	LRRC9	Leucine-rich repeat-containing protein 9. (1433 aa)
	LMO1	LIM domain only 1. (145 aa)
	TAL2	Fukutin isoform X7. (105 aa)
	HOMEZ	Homeobox and leucine zipper protein Homez. (546 aa)
	DLX1	LOW QUALITY PROTEIN: homeobox protein DLX-1. (243 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	RUNX1T1	Protein CBFA2T1. (604 aa)
	OTX2	Homeobox protein OTX2 isoform X1. (297 aa)
	LHX4	LIM/homeobox protein Lhx4. (382 aa)
	NES	Nestin; Belongs to the intermediate filament family. (1482 aa)
	MEF2D	LOW QUALITY PROTEIN: myocyte-specific enhancer factor 2D. (494 aa)
	PAX3	Paired box protein Pax-3 isoform X1. (484 aa)
	SATB1	DNA-binding protein SATB. (753 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (515 aa)
	ENSUMAP00000025747	annotation not available (76 aa)
	LMO2	Rhombotin-2 isoform X2. (155 aa)
	FOXP2	Forkhead box protein P2. (753 aa)
	PAX6	Paired box protein Pax-6 isoform X2. (450 aa)
	RUNX1	Runt-related transcription factor 1. (107 aa)
	CBFB	Core-binding factor subunit beta. (76 aa)
	PAX7	Paired box protein Pax-7 isoform X2. (482 aa)
	SATB2	DNA-binding protein SATB. (703 aa)
	FAM195A	Protein FAM195A isoform X1. (105 aa)
	DLX6	Homeobox protein DLX-6. (167 aa)
	DLX5	Homeobox protein DLX-5. (285 aa)
	LHX1	LOW QUALITY PROTEIN: LIM/homeobox protein Lhx1. (395 aa)
	FERD3L	Fer3 like bHLH transcription factor. (164 aa)
	PPM1D	Protein phosphatase 1D. (546 aa)
	SSBP3	Single-stranded DNA-binding protein 3. (300 aa)
	LMX1A	LIM homeobox transcription factor 1-alpha. (382 aa)
	LHX3	LOW QUALITY PROTEIN: LIM/homeobox protein Lhx3. (62 aa)
	ENSUMAP00000031776	annotation not available (264 aa)
	LDB1	LIM domain-binding protein 1 isoform X1. (375 aa)
	FAM107A	LOW QUALITY PROTEIN: protein FAM107A. (131 aa)
	SOX6	Transcription factor SOX-6 isoform X2. (855 aa)
	DMBX1	LOW QUALITY PROTEIN: diencephalon/mesencephalon homeobox protein 1. (353 aa)
	TCF12	Transcription factor 12 isoform X1. (682 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (316 aa)
	OLIG3	Oligodendrocyte transcription factor 3. (252 aa)
	DACH2	Dachshund homolog 2. (457 aa)
	FOXB1	Forkhead box protein B1. (255 aa)
	FOXP1	Forkhead box protein P1. (679 aa)
	FOXJ3	Forkhead box protein J3 isoform X1. (622 aa)
	TCF21	Transcription factor 21. (179 aa)
	EYA4	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (616 aa)
	LOC103657641	Zinc finger protein ZIC 5-like. (191 aa)
	MEF2A	Myocyte-specific enhancer factor 2A. (466 aa)
	EYA2	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (509 aa)
	LHX9	LIM/homeobox protein Lhx9. (397 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALX3	LDB1	ENSUMAP00000018526	ENSUMAP00000031949	Homeobox protein aristaless-like 3.	LIM domain-binding protein 1 isoform X1.	0.668
ALX3	LDB2	ENSUMAP00000018526	ENSUMAP00000004072	Homeobox protein aristaless-like 3.	LIM domain-binding protein 2 isoform X1.	0.668
ALX3	LHX3	ENSUMAP00000018526	ENSUMAP00000031774	Homeobox protein aristaless-like 3.	LOW QUALITY PROTEIN: LIM/homeobox protein Lhx3.	0.718
ALX3	LHX4	ENSUMAP00000018526	ENSUMAP00000023932	Homeobox protein aristaless-like 3.	LIM/homeobox protein Lhx4.	0.718
ALX3	PAX6	ENSUMAP00000018526	ENSUMAP00000026947	Homeobox protein aristaless-like 3.	Paired box protein Pax-6 isoform X2.	0.564
CBFB	ENSUMAP00000004364	ENSUMAP00000027905	ENSUMAP00000004364	Core-binding factor subunit beta.	annotation not available	0.479
CBFB	FOXP1	ENSUMAP00000027905	ENSUMAP00000033341	Core-binding factor subunit beta.	Forkhead box protein P1.	0.460
CBFB	FOXP2	ENSUMAP00000027905	ENSUMAP00000026360	Core-binding factor subunit beta.	Forkhead box protein P2.	0.460
CBFB	FOXP2-2	ENSUMAP00000027905	ENSUMAP00000009435	Core-binding factor subunit beta.	Forkhead box protein P2.	0.460
CBFB	FOXP4	ENSUMAP00000027905	ENSUMAP00000016560	Core-binding factor subunit beta.	Forkhead box protein P4.	0.460
CBFB	LDB1	ENSUMAP00000027905	ENSUMAP00000031949	Core-binding factor subunit beta.	LIM domain-binding protein 1 isoform X1.	0.582
CBFB	LDB2	ENSUMAP00000027905	ENSUMAP00000004072	Core-binding factor subunit beta.	LIM domain-binding protein 2 isoform X1.	0.574
CBFB	LMO1	ENSUMAP00000027905	ENSUMAP00000019087	Core-binding factor subunit beta.	LIM domain only 1.	0.497
CBFB	LMO2	ENSUMAP00000027905	ENSUMAP00000025852	Core-binding factor subunit beta.	Rhombotin-2 isoform X2.	0.647
CBFB	LMO3	ENSUMAP00000027905	ENSUMAP00000003424	Core-binding factor subunit beta.	LIM domain only protein 3.	0.497
CBFB	LYL1	ENSUMAP00000027905	ENSUMAP00000007836	Core-binding factor subunit beta.	LYL1 basic helix-loop-helix family member.	0.589
CBFB	PAX8	ENSUMAP00000027905	ENSUMAP00000011257	Core-binding factor subunit beta.	Paired box protein Pax-8.	0.456
CBFB	PPM1D	ENSUMAP00000027905	ENSUMAP00000030811	Core-binding factor subunit beta.	Protein phosphatase 1D.	0.768
CBFB	RUNX1	ENSUMAP00000027905	ENSUMAP00000027812	Core-binding factor subunit beta.	Runt-related transcription factor 1.	0.930
CBFB	RUNX3	ENSUMAP00000027905	ENSUMAP00000017838	Core-binding factor subunit beta.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.989