45 items (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RC3H2	Ring finger and CCCH-type domains 2. (1189 aa)
	SPTA1	LOW QUALITY PROTEIN: spectrin alpha chain, erythrocytic 1. (2388 aa)
	PKN1	Serine/threonine-protein kinase N1. (913 aa)
	TNFRSF17	Tumor necrosis factor receptor superfamily member 17. (175 aa)
	SASH3	SAM and SH3 domain-containing protein 3. (321 aa)
	TNFRSF13B	LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 13B. (235 aa)
	MEF2C	Myocyte-specific enhancer factor 2C isoform X3. (433 aa)
	SIT1	Signaling threshold regulating transmembrane adaptor 1. (176 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (601 aa)
	SLC39A3	Solute carrier family 39 member 3. (314 aa)
	FOXP3	Forkhead box protein P3. (314 aa)
	FADD	FAS-associated death domain protein. (192 aa)
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2. (1272 aa)
	ENSUMAP00000009823	annotation not available (299 aa)
	ZC3H8	Zinc finger CCCH domain-containing protein 8 isoform X1. (305 aa)
	GAPT	Protein GAPT. (156 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (534 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	SKIL	Ski-like protein isoform X2. (664 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	PPP2R3C	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X3. (450 aa)
	NCKAP1L	Nck-associated protein 1-like. (1134 aa)
	BCL2L11	Bcl-2-like protein 11 isoform X11. (84 aa)
	FOXN1	LOW QUALITY PROTEIN: forkhead box protein N1. (628 aa)
	LOC103665481	Putative Bcl-2 homologous antagonist/killer 2. (349 aa)
	IL2RA	Interleukin-2 receptor subunit alpha isoform X1. (267 aa)
	FAS	Tumor necrosis factor receptor superfamily member 6 isoform X1. (351 aa)
	TCIRG1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (218 aa)
	ENSUMAP00000017922	annotation not available (78 aa)
	SOS1	Son of sevenless homolog 1. (1276 aa)
	HIF1A	Hypoxia-inducible factor 1-alpha isoform X2. (823 aa)
	IL20RB	Interleukin-20 receptor subunit beta isoform X2. (392 aa)
	LGALS2	Galectin. (132 aa)
	GIMAP5	GTPase IMAP family member 5 isoform X1. (488 aa)
	ABL1	Tyrosine-protein kinase. (1135 aa)
	SLC46A2	Thymic stromal cotransporter homolog. (468 aa)
	RC3H1	Ring finger and CCCH-type domains 1. (1133 aa)
	TNFSF13B	Tumor necrosis factor ligand superfamily member 13B; Belongs to the tumor necrosis factor family. (293 aa)
	RIPK3	Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily. (487 aa)
	STAT5B	Signal transducer and activator of transcription. (787 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (840 aa)
	TNFAIP3	Tumor necrosis factor alpha-induced protein 3. (714 aa)
	STAT5A	Signal transducer and activator of transcription. (793 aa)
	ADA	Adenosine deaminase isoform X4. (423 aa)
	TRAF3IP2	TRAF3 interacting protein 2. (563 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	NCKAP1L	ENSUMAP00000025680	ENSUMAP00000015368	Tyrosine-protein kinase.	Nck-associated protein 1-like.	0.557
ABL1	STAT5A	ENSUMAP00000025680	ENSUMAP00000034681	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.928
ABL1	STAT5B	ENSUMAP00000025680	ENSUMAP00000032319	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.928
BCL2L11	LOC103665481	ENSUMAP00000015720	ENSUMAP00000016562	Bcl-2-like protein 11 isoform X11.	Putative Bcl-2 homologous antagonist/killer 2.	0.916
ENSUMAP00000009823	LYN	ENSUMAP00000009823	ENSUMAP00000013226	annotation not available	Tyrosine-protein kinase.	0.738
ENSUMAP00000009823	SOS1	ENSUMAP00000009823	ENSUMAP00000018200	annotation not available	Son of sevenless homolog 1.	0.413
FADD	FAS	ENSUMAP00000009429	ENSUMAP00000016893	FAS-associated death domain protein.	Tumor necrosis factor receptor superfamily member 6 isoform X1.	0.999
FADD	LOC103665481	ENSUMAP00000009429	ENSUMAP00000016562	FAS-associated death domain protein.	Putative Bcl-2 homologous antagonist/killer 2.	0.436
FADD	RIPK3	ENSUMAP00000009429	ENSUMAP00000031815	FAS-associated death domain protein.	Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily.	0.994
FADD	TNFAIP3	ENSUMAP00000009429	ENSUMAP00000033041	FAS-associated death domain protein.	Tumor necrosis factor alpha-induced protein 3.	0.615
FAS	FADD	ENSUMAP00000016893	ENSUMAP00000009429	Tumor necrosis factor receptor superfamily member 6 isoform X1.	FAS-associated death domain protein.	0.999
FAS	FOXP3	ENSUMAP00000016893	ENSUMAP00000009206	Tumor necrosis factor receptor superfamily member 6 isoform X1.	Forkhead box protein P3.	0.511
FAS	RIPK3	ENSUMAP00000016893	ENSUMAP00000031815	Tumor necrosis factor receptor superfamily member 6 isoform X1.	Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily.	0.476
FOXP3	FAS	ENSUMAP00000009206	ENSUMAP00000016893	Forkhead box protein P3.	Tumor necrosis factor receptor superfamily member 6 isoform X1.	0.511
FOXP3	HIF1A	ENSUMAP00000009206	ENSUMAP00000018657	Forkhead box protein P3.	Hypoxia-inducible factor 1-alpha isoform X2.	0.710
FOXP3	IL2RA	ENSUMAP00000009206	ENSUMAP00000016645	Forkhead box protein P3.	Interleukin-2 receptor subunit alpha isoform X1.	0.770
FOXP3	STAT5A	ENSUMAP00000009206	ENSUMAP00000034681	Forkhead box protein P3.	Signal transducer and activator of transcription.	0.606
HIF1A	FOXP3	ENSUMAP00000018657	ENSUMAP00000009206	Hypoxia-inducible factor 1-alpha isoform X2.	Forkhead box protein P3.	0.710
IL2RA	FOXP3	ENSUMAP00000016645	ENSUMAP00000009206	Interleukin-2 receptor subunit alpha isoform X1.	Forkhead box protein P3.	0.770
IL2RA	STAT5A	ENSUMAP00000016645	ENSUMAP00000034681	Interleukin-2 receptor subunit alpha isoform X1.	Signal transducer and activator of transcription.	0.954