(21 nodes) Epithelial structure maintenance network (Ursus maritimus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SRF	Serum response factor. (446 aa)
	CRACD	Uncharacterized protein KIAA1211 homolog. (1196 aa)
	PBLD	Phenazine biosynthesis like protein domain containing. (288 aa)
	PIWIL4	Piwi-like protein 4; Belongs to the argonaute family. (848 aa)
	NOD2	Nucleotide-binding oligomerization domain-containing protein 2. (817 aa)
	MUC6	LOW QUALITY PROTEIN: mucin-6. (345 aa)
	IL17A	interleukin-17A. (161 aa)
	TLR4	Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
	LDB2	LIM domain-binding protein 2 isoform X1. (373 aa)
	STRAP	Serine/threonine kinase receptor associated protein. (350 aa)
	TFF3	Trefoil factor 3. (80 aa)
	TFF2	Trefoil factor 2. (137 aa)
	ILDR1	Immunoglobulin-like domain-containing receptor 1. (510 aa)
	MUC13	Mucin 13, cell surface associated. (549 aa)
	LDB1	LIM domain-binding protein 1 isoform X1. (375 aa)
	MKS1	MKS transition zone complex subunit 1. (559 aa)
	LSR	Lipolysis-stimulated lipoprotein receptor. (598 aa)
	ZNF830	Zinc finger protein 830. (370 aa)
	CXADR	Coxsackievirus and adenovirus receptor isoform X2. (343 aa)
	CROCC2	Putative ciliary rootlet coiled-coil protein-like 3 protein. (1537 aa)
	VSIG1	V-set and immunoglobulin domain-containing protein 1. (363 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL17A	NOD2	ENSUMAP00000005530	ENSUMAP00000007686	interleukin-17A.	Nucleotide-binding oligomerization domain-containing protein 2.	0.489
IL17A	TLR4	ENSUMAP00000005530	ENSUMAP00000005351	interleukin-17A.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.635
MUC13	MUC6	ENSUMAP00000035018	ENSUMAP00000007659	Mucin 13, cell surface associated.	LOW QUALITY PROTEIN: mucin-6.	0.733
MUC13	TFF3	ENSUMAP00000035018	ENSUMAP00000035537	Mucin 13, cell surface associated.	Trefoil factor 3.	0.475
MUC6	MUC13	ENSUMAP00000007659	ENSUMAP00000035018	LOW QUALITY PROTEIN: mucin-6.	Mucin 13, cell surface associated.	0.733
MUC6	TFF2	ENSUMAP00000007659	ENSUMAP00000035536	LOW QUALITY PROTEIN: mucin-6.	Trefoil factor 2.	0.607
MUC6	TFF3	ENSUMAP00000007659	ENSUMAP00000035537	LOW QUALITY PROTEIN: mucin-6.	Trefoil factor 3.	0.645
NOD2	IL17A	ENSUMAP00000007686	ENSUMAP00000005530	Nucleotide-binding oligomerization domain-containing protein 2.	interleukin-17A.	0.489
NOD2	TLR4	ENSUMAP00000007686	ENSUMAP00000005351	Nucleotide-binding oligomerization domain-containing protein 2.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.673
PBLD	STRAP	ENSUMAP00000009590	ENSUMAP00000003326	Phenazine biosynthesis like protein domain containing.	Serine/threonine kinase receptor associated protein.	0.469
STRAP	PBLD	ENSUMAP00000003326	ENSUMAP00000009590	Serine/threonine kinase receptor associated protein.	Phenazine biosynthesis like protein domain containing.	0.469
TFF2	MUC6	ENSUMAP00000035536	ENSUMAP00000007659	Trefoil factor 2.	LOW QUALITY PROTEIN: mucin-6.	0.607
TFF3	MUC13	ENSUMAP00000035537	ENSUMAP00000035018	Trefoil factor 3.	Mucin 13, cell surface associated.	0.475
TFF3	MUC6	ENSUMAP00000035537	ENSUMAP00000007659	Trefoil factor 3.	LOW QUALITY PROTEIN: mucin-6.	0.645
TLR4	IL17A	ENSUMAP00000005351	ENSUMAP00000005530	Toll-like receptor 4; Belongs to the Toll-like receptor family.	interleukin-17A.	0.635
TLR4	NOD2	ENSUMAP00000005351	ENSUMAP00000007686	Toll-like receptor 4; Belongs to the Toll-like receptor family.	Nucleotide-binding oligomerization domain-containing protein 2.	0.673