STRINGSTRING
ENSUMAP00000015139 ENSUMAP00000015139 IGFBP3 IGFBP3 DOCK4 DOCK4 ABHD2 ABHD2 PDGFA PDGFA MEF2C MEF2C PDGFRB PDGFRB TLR4 TLR4 ADIPOQ ADIPOQ SLIT2 SLIT2 IGFBP5 IGFBP5 AIF1 AIF1 NF1 NF1 ADAMTS1 ADAMTS1 PDGFB PDGFB NDRG4 NDRG4 PLXNA1 PLXNA1 DOCK7 DOCK7 BMPR1A BMPR1A CORO1B CORO1B NR4A3 NR4A3 PLAU PLAU VTN VTN PRKG1 PRKG1 SEMA6D SEMA6D TRIB1 TRIB1 SORL1 SORL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUMAP00000015139annotation not available (194 aa)
IGFBP3Insulin-like growth factor-binding protein 3. (102 aa)
DOCK4Dedicator of cytokinesis protein 4; Belongs to the DOCK family. (1970 aa)
ABHD2Abhydrolase domain-containing protein 2 isoform X1. (425 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (288 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X3. (433 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1152 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
ADIPOQAdiponectin isoform X2. (297 aa)
SLIT2Slit homolog 2 protein isoform X1. (1530 aa)
IGFBP5Insulin-like growth factor-binding protein 5. (271 aa)
AIF1Leukocyte-specific transcript 1 protein. (191 aa)
NF1Neurofibromin. (2862 aa)
ADAMTS1A disintegrin and metalloproteinase with thrombospondin motifs 1. (736 aa)
PDGFBPlatelet-derived growth factor subunit B. (234 aa)
NDRG4Protein NDRG4 isoform X1. (356 aa)
PLXNA1LOW QUALITY PROTEIN: plexin-A1. (1729 aa)
DOCK7Dedicator of cytokinesis protein 7; Belongs to the DOCK family. (2242 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (408 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (567 aa)
PLAUUrokinase-type plasminogen activator; Belongs to the peptidase S1 family. (432 aa)
VTNVitronectin. (470 aa)
PRKG1cGMP-dependent protein kinase 1. (472 aa)
SEMA6Dsemaphorin-6D isoform X1; Belongs to the semaphorin family. (1086 aa)
TRIB1Tribbles homolog 1. (191 aa)
SORL1Sortilin-related receptor. (2185 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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