(16 nodes) Platelet formation network (Ursus maritimus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (600 aa)
	EP300	LOW QUALITY PROTEIN: histone acetyltransferase p300. (2390 aa)
	MYH9	LOW QUALITY PROTEIN: myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2048 aa)
	CLEC1B	C-type lectin domain family 1 member B isoform X1. (307 aa)
	MPIG6B	Protein G6b. (205 aa)
	ZNF385A	Zinc finger protein 385A. (244 aa)
	ENSUMAP00000013744	annotation not available (494 aa)
	ENSUMAP00000013740	annotation not available (351 aa)
	SRF	Serum response factor. (446 aa)
	ENSUMAP00000010815	annotation not available (220 aa)
	CIB1	Calcium and integrin-binding protein 1. (199 aa)
	GATA1	LOW QUALITY PROTEIN: erythroid transcription factor. (438 aa)
	VPS33A	Vacuolar protein sorting-associated protein 33A; Belongs to the STXBP/unc-18/SEC1 family. (616 aa)
	MEF2C	Myocyte-specific enhancer factor 2C isoform X3. (433 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type 6. (592 aa)
	WDR1	WD repeat-containing protein 1. (612 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLEC1B	MPIG6B	ENSUMAP00000022260	ENSUMAP00000019220	C-type lectin domain family 1 member B isoform X1.	Protein G6b.	0.435
CLEC1B	PTPN11	ENSUMAP00000022260	ENSUMAP00000013400	C-type lectin domain family 1 member B isoform X1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.428
CLEC1B	PTPN6	ENSUMAP00000022260	ENSUMAP00000005099	C-type lectin domain family 1 member B isoform X1.	Tyrosine-protein phosphatase non-receptor type 6.	0.427
ENSUMAP00000010815	EP300	ENSUMAP00000010815	ENSUMAP00000029965	annotation not available	LOW QUALITY PROTEIN: histone acetyltransferase p300.	0.464
ENSUMAP00000010815	GATA1	ENSUMAP00000010815	ENSUMAP00000010218	annotation not available	LOW QUALITY PROTEIN: erythroid transcription factor.	0.979
ENSUMAP00000013740	ENSUMAP00000013744	ENSUMAP00000013740	ENSUMAP00000013744	annotation not available	annotation not available	0.916
ENSUMAP00000013740	MYH9	ENSUMAP00000013740	ENSUMAP00000022783	annotation not available	LOW QUALITY PROTEIN: myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.574
ENSUMAP00000013744	ENSUMAP00000013740	ENSUMAP00000013744	ENSUMAP00000013740	annotation not available	annotation not available	0.916
ENSUMAP00000013744	MYH9	ENSUMAP00000013744	ENSUMAP00000022783	annotation not available	LOW QUALITY PROTEIN: myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.574
EP300	ENSUMAP00000010815	ENSUMAP00000029965	ENSUMAP00000010815	LOW QUALITY PROTEIN: histone acetyltransferase p300.	annotation not available	0.464
EP300	GATA1	ENSUMAP00000029965	ENSUMAP00000010218	LOW QUALITY PROTEIN: histone acetyltransferase p300.	LOW QUALITY PROTEIN: erythroid transcription factor.	0.723
EP300	MEF2C	ENSUMAP00000029965	ENSUMAP00000006803	LOW QUALITY PROTEIN: histone acetyltransferase p300.	Myocyte-specific enhancer factor 2C isoform X3.	0.627
GATA1	ENSUMAP00000010815	ENSUMAP00000010218	ENSUMAP00000010815	LOW QUALITY PROTEIN: erythroid transcription factor.	annotation not available	0.979
GATA1	EP300	ENSUMAP00000010218	ENSUMAP00000029965	LOW QUALITY PROTEIN: erythroid transcription factor.	LOW QUALITY PROTEIN: histone acetyltransferase p300.	0.723
MEF2C	EP300	ENSUMAP00000006803	ENSUMAP00000029965	Myocyte-specific enhancer factor 2C isoform X3.	LOW QUALITY PROTEIN: histone acetyltransferase p300.	0.627
MPIG6B	CLEC1B	ENSUMAP00000019220	ENSUMAP00000022260	Protein G6b.	C-type lectin domain family 1 member B isoform X1.	0.435
MPIG6B	PTPN11	ENSUMAP00000019220	ENSUMAP00000013400	Protein G6b.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.856
MPIG6B	PTPN6	ENSUMAP00000019220	ENSUMAP00000005099	Protein G6b.	Tyrosine-protein phosphatase non-receptor type 6.	0.843
MYH9	ENSUMAP00000013740	ENSUMAP00000022783	ENSUMAP00000013740	LOW QUALITY PROTEIN: myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	annotation not available	0.574
MYH9	ENSUMAP00000013744	ENSUMAP00000022783	ENSUMAP00000013744	LOW QUALITY PROTEIN: myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	annotation not available	0.574