STRINGSTRING
MAPK1 MAPK1 NKX2-2 NKX2-2 FGF10 FGF10 PAX8 PAX8 SRF SRF MAPK3 MAPK3 SMAD3 SMAD3 BRAF BRAF EDNRA EDNRA RAF1 RAF1 EDN1 EDN1 HESX1 HESX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK1Mitogen-activated protein kinase. (363 aa)
NKX2-2NK2 homeobox 2. (306 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
PAX8Paired box protein Pax-8. (459 aa)
SRFSerum response factor. (446 aa)
MAPK3Mitogen-activated protein kinase. (354 aa)
SMAD3Mothers against decapentaplegic homolog. (280 aa)
BRAFSerine/threonine-protein kinase B-raf. (715 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
EDN1Endothelin-1. (202 aa)
HESX1Homeobox expressed in ES cells 1. (181 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.